3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Dementia Praecox

3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide has been researched along with Dementia Praecox in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	37 (55.22)	18.2507
2000's	27 (40.30)	29.6817
2010's	2 (2.99)	24.3611
2020's	1 (1.49)	2.80

Authors

Authors	Studies
Bramon, E; Chen, KC; Chen, PS; Chiu, NT; David, AS; Howes, OD; Lee, IH; Yang, YK; Yeh, TL	1
Boerner, R; Dresel, S; Frodl, T; Gründer, G; Hahn, K; la Fougère, C; Meisenzahl, EM; Möller, HJ; Scheuerecker, J; Schmitt, G; Schwarz, M; Stauss, J	1
Abi-Dargham, A; Kegeles, LS; Laruelle, M; Slifstein, M; van de Giessen, E	1
Dresel, S; Frodl, T; Hahn, K; La Fougère, C; Meisenzahl, EM; Möller, HJ; Schmitt, GJ	2
Boerner, R; Dresel, S; Frodl, T; Hahn, K; la Fougère, C; Meisenzahl, EM; Möller, HJ; Schmitt, GJ	1
Dehning, S; Karch, S; Koch, W; Möller, HJ; Müller, N; Poepperl, G; Pogarell, O; Tatsch, K	1
Dresel, S; Frodl, T; Hahn, K; Meisenzahl, EM; Möller, HJ; Preuss, UW; Rossmüller, B; Schmitt, GJ; Tatsch, K	1
Chen, CC; Chen, M; Chiu, NT; Lee, IH; Yang, YK; Yeh, TL	1
Bernardo, M; Catafau, AM; Font, M; Gutiérrez, F; Lomeña, F; Parellada, E; Pavía, J	1
Bernardo, M; Catafau, AM; Fernández-Egea, E; Font, M; Gutierrez, F; Lomeña, F; Parellada, E; Pavía, J	1
Bédard, MA; Elie, A; Lévesque, M; Paquet, F; Soucy, JP; Stip, E	1
Abi-Dargham, A; Cangiano, C; Frankle, WG; Gil, R; Gorman, JM; Hackett, E; Kochan, LD; Laruelle, M; Mawlawi, O; Slifstein, M; Zea-Ponce, Y; Zhu, Z	1
Awad, AG; Voruganti, LP	1
Chen, PS; Chiu, NT; Lee, IH; Yang, YK; Yeh, TL; Yu, L	1
Chen, PS; Chiu, NT; Jeffries, KJ; Lee, IH; Lee, LC; Yang, YK; Yeh, TL	1
Ambrus, E; Argyelán, M; Csernay, L; Janka, Z; Kanyó, B; Kéri, S; Kovács, Z; Pávics, L; Szekeres, G	1
Booij, J; de Haan, L; Lavalaye, J; Linszen, D	1
Alvarez, E; Carrió, I; Catafau, AM; Corripio, I; Martin, JC; Pérez, V; Schotte, A	1
Bullich, S; Catafau, AM; Corripio, I; García-Ribera, C; Gomeni, R; Merlo-Pich, E; Nucci, G; Parellada, E; Penengo, MM	1
Busatto, GF; Costa, DC; Ell, PJ; Kerwin, RW; Pilowsky, LS; Verhoeff, NP	2
Costa, DC; Ell, PJ; Kerwin, RW; Murray, RM; Pilowsky, LS; Verhoeff, NP	3
Costa, DC; Ell, PJ; Gray, NS; Hemsley, DR; Kerwin, RW; Pedro, BM; Pilowsky, LS; Verhoeff, NP	1
Gray, JA; Gray, NS; Kerwin, RW; Pilowsky, LS	1
Biersack, HJ; Briele, B; Broich, K; Danos, P; Grünwald, F; Hotze, AL; Kasper, S; Klemm, E; Krappel, C; Menzel, C; Möller, HJ; Reichmann, K; Rieker, O	1
Abi-Dargham, A; Baldwin, RM; Charney, DS; D'Souza, CD; Erdos, J; Fingado, C; Gil, R; Innis, RB; Krystal, JH; Laruelle, M; McCance, E; Rosenblatt, W; Seibyl, JP; van Dyck, CH; Zoghbi, SS	1
Busatto, GF; Costa, DC; Ell, PJ; Kerwin, RW; Nohria, V; Pilowsky, LS; Sharma, T; Sigmundsson, T; Taylor, M	1
Bartko, JJ; Breier, A; Coppola, R; Gorey, J; Hsiao, J; Knable, MB; Lee, KS; Malhotra, AK; Pickar, D; Su, TP; Weinberger, DR	1
Acton, PD; Costa, DC; Ell, PJ; Pilowsky, LS	1
Hirschowitz, J; Machac, J; Vallabhajosula, S	1
Asenbaum, S; Brücke, T; Gössler, R; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J; Topitz-Schratzberger, A; Vesely, C	1
Hirschowitz, J; Hitzemann, R; Vallabhajosula, S	1
Innis, RB	1
Asenbaum, S; Brücke, T; Kasper, S; Küfferle, B; Tauscher, J	1
Breier, A; Hadd, K; Malhotra, AK; Pickar, D; Su, TP	1
Bubeck, B; Demisch, S; Sauer, H; Schröder, J; Silvestri, S	1
Asenbaum, S; Brücke, T; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J; Vesely, C	1
Junhold, U; Künstler, U; Preiss, R; Regenthal, R	1
Asenbaum, S; Barnas, C; Brücke, T; Hesselmann, B; Kasper, S; Küfferle, B; Podreka, I; Tauscher, J	1
Abi-Dargham, A; Baldwin, RM; Bowers, M; Charney, DS; Gil, R; Innis, RB; Krystal, J; Laruelle, M; Seibyl, JP; van Dyck, CH	1
Coppola, R; Gorey, JG; Heinz, A; Jones, DW; Knable, MB; Lee, KS; Weinberger, DR	1
Dähne, I; Dresel, S; Hahn, K; Mager, T; Scherer, J; Tatsch, K	1
Klimke, A; Larisch, R	1
Biersack, HJ; Broich, K; Grünwald, F; Kasper, S; Klemm, E; Möller, HJ	1
Asenbaum, S; Barnas, C; Brücke, T; Fischer, P; Kasper, S; Küfferle, B; Pezawas, L; Tauscher, J; Tauscher-Wisniewski, S	1
Dresel, S; Hahn, K; Mager, T; Meisenzahl, E; Möller, HJ; Rossmüller, B; Tatsch, K	1
Egan, MF; Knable, MB; Lafargue, T; Pickar, D; Raedler, TJ; Urbina, RA; Weinberger, DR	1
Andreas, J; Benkert, O; Eissner, D; Gründer, G; Heydari, N; Müller, MJ; Nickel, O; Schlegel, S; Schlösser, R; Wetzel, H	1
Abi-Dargham, A; Laruelle, M	1
Booij, J; Gersons, BP; Lavalaye, J; Linszen, DH; Reneman, L; van Royen, EA	1
Holzmann, T; Hör, G; Maul, FD; Pflug, B; Schreiner, M; Volk, S; Weppner, M	1
Fujita, M; Innis, RB; Kugaya, A	1
Booij, J; de Haan, L; Dingemans, PM; Lavalaye, J; Linszen, D	1
Kapur, S; Seeman, P	1
Abi-Dargham, A; Carlsson, A; Cooper, TB; Kegeles, LS; Laruelle, M; Mann, JJ; Rodenhiser-Hill, J; Van Heertum, RL; Zea-Ponce, Y	1
Harrison, PJ	1
Dresel, S; Frodl, T; Hahn, K; Mager, T; Meisenzahl, EM; Möller, HJ; Preuss, UW; Rossmüller, B; Schmitt, GJ; Tatsch, K	1
Abi-Dargham, A; Gelernter, J; Innis, RB; Kegeles, L; Laruelle, M; Martinez, D; van Dyck, CH	1
Bressan, RA; Ell, PJ; Jones, HM; Pilowsky, LS	1
Bernardo, M; Catafau, AM; Font, M; Gómez, JC; Gutiérrez, F; Lomeña, F; López-Carrero, C; Parellada, E; Pavía, J; Salamero, M	1
Awad, AG; Costa, G; Mattar, A; Slomka, P; So, A; Voruganti, L; Zabel, P	1
Cowen, PJ; Ellis, PM; Geaney, DP; Shepstone, BJ; Soper, N	1
Benzer, MK; Fritzche, H; Konig, P	1
Barrett, J; Bobeldijk, M; Costa, DC; Cullum, ID; Ell, PJ; Palazidou, E; Syed, GM; Toone, B; Van Royen, E; Verhoeff, NP	1

Reviews

3 review(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Dementia Praecox

Article	Year
Is neuroleptic dysphoria a variant of drug-induced extrapyramidal side effects? Canadian journal of psychiatry. Revue canadienne de psychiatrie, 2004, Volume: 49, Issue:5 Topics: Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Brain; Cognition Disorders; Contrast Media; Cross-Sectional Studies; Dopamine; Follow-Up Studies; Humans; Motivation; Nucleus Accumbens; Parkinsonian Disorders; Pyrrolidines; Schizophrenia; Time Factors; Tomography, Emission-Computed	2004
Dopamine as the wind of the psychotic fire: new evidence from brain imaging studies. Journal of psychopharmacology (Oxford, England), 1999, Volume: 13, Issue:4 Topics: Animals; Benzamides; Brain; Dopamine; Humans; Iodine Radioisotopes; Pyrrolidines; Receptors, Dopamine; Schizophrenia; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1999
Applications of SPECT imaging of dopaminergic neurotransmission in neuropsychiatric disorders. Annals of nuclear medicine, 2000, Volume: 14, Issue:1 Topics: Animals; Benzamides; Brain; Carrier Proteins; Cocaine; Disease Progression; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon	2000

Trials

14 trial(s) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Dementia Praecox

Article	Year
Striatal D2/D3 receptor occupancy, clinical response and side effects with amisulpride: an iodine-123-iodobenzamide SPET study. Pharmacopsychiatry, 2008, Volume: 41, Issue:5 Topics: Adult; Amisulpride; Antipsychotic Agents; Benzamides; Corpus Striatum; Dose-Response Relationship, Drug; Female; Humans; Iodine Radioisotopes; Male; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Severity of Illness Index; Statistics, Nonparametric; Sulpiride; Tomography, Emission-Computed, Single-Photon	2008
Striatal dopamine D2 receptor binding of risperidone in schizophrenic patients as assessed by 123I-iodobenzamide SPECT: a comparative study with olanzapine. Journal of psychopharmacology (Oxford, England), 2002, Volume: 16, Issue:3 Topics: Adult; Aged; Antipsychotic Agents; Benzamides; Benzodiazepines; Contrast Media; Corpus Striatum; Dopamine D2 Receptor Antagonists; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Olanzapine; Pirenzepine; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2002
Comparison between olanzapine and haloperidol on procedural learning and the relationship with striatal D2 receptor occupancy in schizophrenia. The Journal of neuropsychiatry and clinical neurosciences, 2004,Winter, Volume: 16, Issue:1 Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzamides; Benzodiazepines; Case-Control Studies; Corpus Striatum; Female; Functional Laterality; Haloperidol; Humans; Learning; Male; Olanzapine; Psychiatric Status Rating Scales; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2004
Occupancy of dopamine D2 receptors by the atypical antipsychotic drugs risperidone and olanzapine: theoretical implications. Psychopharmacology, 2004, Volume: 175, Issue:4 Topics: Adult; Algorithms; Antipsychotic Agents; Benzamides; Benzodiazepines; Dopamine; Female; Humans; Male; Olanzapine; Psychiatric Status Rating Scales; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2004
The prognostic value of dopamine receptor occupancy by [123I]IBZM-SPECT in schizophrenic patients treated with quetiapine. Nuclear medicine review. Central & Eastern Europe, 2004, Volume: 7, Issue:2 Topics: Adult; Antipsychotic Agents; Benzamides; Corpus Striatum; Dibenzothiazepines; Female; Humans; Male; Prognosis; Pyrrolidines; Quetiapine Fumarate; Radiopharmaceuticals; Receptors, Dopamine D2; Schizophrenia; Severity of Illness Index; Tissue Distribution; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	2004
Dopamine D2 receptor blockade in vivo with the novel antipsychotics risperidone and remoxipride--an 123I-IBZM single photon emission tomography (SPET) study. Psychopharmacology, 1995, Volume: 117, Issue:1 Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Cerebral Cortex; Dopamine D2 Receptor Antagonists; Female; Humans; Image Processing, Computer-Assisted; Iodine Radioisotopes; Isoxazoles; Male; Middle Aged; Neostriatum; Piperidines; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Remoxipride; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1995
IBZM SPECT imaging of striatal dopamine-2 receptors in psychotic patients treated with the novel antipsychotic substance quetiapine in comparison to clozapine and haloperidol. Psychopharmacology, 1997, Volume: 133, Issue:4 Topics: Adult; Antipsychotic Agents; Benzamides; Clozapine; Dibenzothiazepines; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Middle Aged; Neostriatum; Psychotic Disorders; Pyrrolidines; Quetiapine Fumarate; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1997
D2-dopamine receptor occupancy measured by IBZM-SPECT in relation to extrapyramidal side effects. Pharmacopsychiatry, 1998, Volume: 31, Issue:5 Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Clozapine; Dose-Response Relationship, Drug; Female; Frontal Lobe; Humans; Male; Neostriatum; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1998
In vivo 123I IBZM SPECT imaging of striatal dopamine-2 receptor occupancy in schizophrenic patients treated with olanzapine in comparison to clozapine and haloperidol. Psychopharmacology, 1999, Volume: 141, Issue:2 Topics: Adult; Analysis of Variance; Antipsychotic Agents; Benzamides; Benzodiazepines; Clozapine; Contrast Media; Corpus Striatum; Female; Haloperidol; Humans; Iodine Radioisotopes; Male; Middle Aged; Olanzapine; Pirenzepine; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	1999
Dopamine D2 receptor occupancy by olanzapine or risperidone in young patients with schizophrenia. Psychiatry research, 1999, Nov-08, Volume: 92, Issue:1 Topics: Adolescent; Adult; Antipsychotic Agents; Benzamides; Benzodiazepines; Brain; Brain Mapping; Contrast Media; Female; Humans; Iodine Radioisotopes; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	1999
Modulation of amphetamine-induced striatal dopamine release by ketamine in humans: implications for schizophrenia. Biological psychiatry, 2000, Oct-01, Volume: 48, Issue:7 Topics: Adult; Amphetamine; Benzamides; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Antagonists; Excitatory Amino Acid Antagonists; Female; Humans; Ketamine; Male; Prefrontal Cortex; Pyrrolidines; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon	2000
D2 receptor occupancy under recommended and high doses of olanzapine: an iodine-123-iodobenzamide SPECT study. Journal of psychopharmacology (Oxford, England), 2000, Volume: 14, Issue:4 Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Benzodiazepines; Brain; Brain Chemistry; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Olanzapine; Pirenzepine; Psychotic Disorders; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2000
Double-blind olanzapine vs. haloperidol D2 dopamine receptor blockade in schizophrenic patients: a baseline-endpoint. Psychiatry research, 2001, Aug-25, Volume: 107, Issue:2 Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Benzodiazepines; Contrast Media; Corpus Striatum; Double-Blind Method; Female; Frontal Lobe; Haloperidol; Humans; Male; Olanzapine; Pirenzepine; Prospective Studies; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2001
Subjective effects of AMPT-induced dopamine depletion in schizophrenia: correlation between dysphoric responses and striatal D(2) binding ratios on SPECT imaging. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 25, Issue:5 Topics: Adult; Affect; alpha-Methyltyrosine; Benzamides; Dopamine; Enzyme Inhibitors; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Neostriatum; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	2001

Other Studies

50 other study(ies) available for 3-iodo-2-hydroxy-6-methoxy-n-((1-ethyl-2-pyrrolidinyl)methyl)benzamide and Dementia Praecox

Article	Year
Striatal dopamine D Psychological medicine, 2022, Volume: 52, Issue:14 Topics: Corpus Striatum; Dopamine; Dopamine Antagonists; Humans; Infant, Newborn; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2022
Baseline and amphetamine-stimulated dopamine activity are related in drug-naïve schizophrenic subjects. Biological psychiatry, 2009, Jun-15, Volume: 65, Issue:12 Topics: Adult; alpha-Methyltyrosine; Amphetamine; Benzamides; Dopamine; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Female; Humans; Image Processing, Computer-Assisted; Male; Neostriatum; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Young Adult	2009
Increase of striatal dopamine transmission in first episode drug-naive schizophrenic patients as demonstrated by [(123)I]IBZM SPECT. Psychiatry research, 2009, Sep-30, Volume: 173, Issue:3 Topics: Adult; Benzamides; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Humans; Male; Protein Binding; Psychiatric Status Rating Scales; Pyrrolidines; Schizophrenia; Statistics as Topic; Tomography, Emission-Computed, Single-Photon; Young Adult	2009
Dual-isotope SPECT imaging of striatal dopamine: a comparative study between never-treated and haloperidol-treated first-episode schizophrenic patients. European archives of psychiatry and clinical neuroscience, 2012, Volume: 262, Issue:3 Topics: Adolescent; Adult; Analysis of Variance; Benzamides; Corpus Striatum; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Haloperidol; Humans; Male; Organotechnetium Compounds; Protein Binding; Psychiatric Status Rating Scales; Pyrrolidines; Radiopharmaceuticals; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Tropanes; Young Adult	2012
Dopaminergic neurotransmission in patients with schizophrenia in relation to positive and negative symptoms. Pharmacopsychiatry, 2012, Volume: 45 Suppl 1 Topics: Adolescent; Adult; Benzamides; Central Nervous System Stimulants; Dextroamphetamine; Diagnostic and Statistical Manual of Mental Disorders; Dopamine; Female; Humans; Image Processing, Computer-Assisted; Male; Pyrrolidines; Receptors, Dopamine D2; Receptors, Presynaptic; Schizophrenia; Schizophrenic Psychology; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon; Young Adult	2012
Correlation between fine motor activity and striatal dopamine D2 receptor density in patients with schizophrenia and healthy controls. Psychiatry research, 2003, Jul-30, Volume: 123, Issue:3 Topics: Adolescent; Adult; Benzamides; Cell Count; Contrast Media; Corpus Striatum; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Male; Middle Aged; Psychomotor Performance; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2003
Striatal dopamine D2 receptor density in neuroleptic-naive and in neuroleptic-free schizophrenic patients: an 123I-IBZM-SPECT study. Psychopharmacology, 2004, Volume: 172, Issue:2 Topics: Adult; Antipsychotic Agents; Benzamides; Corpus Striatum; Female; Humans; Male; Protein Binding; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Statistics, Nonparametric; Tomography, Emission-Computed, Single-Photon	2004
Lack of sex differences in striatal dopamine D2 receptor binding in drug-naive schizophrenic patients: an IBZM-SPECT study. Psychiatry research, 2004, Jan-15, Volume: 130, Issue:1 Topics: Adult; Basal Ganglia; Benzamides; Binding, Competitive; Contrast Media; Corpus Striatum; Female; Frontal Lobe; Functional Laterality; Humans; Male; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Sex Factors; Tomography, Emission-Computed, Single-Photon	2004
Associated alterations of striatal dopamine D2/D3 receptor and transporter binding in drug-naive patients with schizophrenia: a dual-isotope SPECT study. The American journal of psychiatry, 2004, Volume: 161, Issue:8 Topics: Adolescent; Adult; Benzamides; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Female; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Neurons; Organotechnetium Compounds; Pyrrolidines; Radiopharmaceuticals; Receptors, Dopamine D2; Receptors, Dopamine D3; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Tropanes	2004
Association between cognitive performance and striatal dopamine binding is higher in timing and motor tasks in patients with schizophrenia. Psychiatry research, 2004, Sep-15, Volume: 131, Issue:3 Topics: Adult; Attention; Benzamides; Cognition Disorders; Corpus Striatum; Discrimination Learning; Dopamine; Female; Humans; Iodine Radioisotopes; Male; Middle Aged; Motor Activity; Neuropsychological Tests; Pattern Recognition, Visual; Psychomotor Performance; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Statistics as Topic; Time Perception; Tomography, Emission-Computed, Single-Photon	2004
Comfort, self-confidence, safety, and dopamine D2 receptor occupancy by antipsychotics. The American journal of psychiatry, 2005, Volume: 162, Issue:8 Topics: Adult; Antipsychotic Agents; Benzamides; Female; Humans; Male; Personal Satisfaction; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Safety; Schizophrenia; Schizophrenic Psychology; Self Efficacy; Tomography, Emission-Computed, Single-Photon	2005
Dopamine D2 receptor occupancy by risperidone: implications for the timing and magnitude of clinical response. Psychiatry research, 2006, Dec-01, Volume: 148, Issue:2-3 Topics: Adolescent; Adult; Antipsychotic Agents; Benzamides; Brief Psychiatric Rating Scale; Corpus Striatum; Dominance, Cerebral; Female; Frontal Lobe; Humans; Male; Middle Aged; Occipital Lobe; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	2006
Dual-isotope SPECT imaging of striatal dopamine: first episode, drug naïve schizophrenic patients. Schizophrenia research, 2008, Volume: 101, Issue:1-3 Topics: Adult; Analysis of Variance; Benzamides; Corpus Striatum; Dopamine; Female; Humans; Male; Organotechnetium Compounds; Psychiatric Status Rating Scales; Pyrrolidines; Schizophrenia; Tomography, Emission-Computed, Single-Photon; Tropanes	2008
Pharmacokinetics and time-course of D(2) receptor occupancy induced by atypical antipsychotics in stabilized schizophrenic patients. Journal of psychopharmacology (Oxford, England), 2008, Volume: 22, Issue:8 Topics: Adult; Antipsychotic Agents; Benzamides; Female; Humans; Male; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2008
Dopamine D2 receptor occupancy in vivo and response to the new antipsychotic risperidone. The British journal of psychiatry : the journal of mental science, 1993, Volume: 163 Topics: Adult; Antipsychotic Agents; Benzamides; Brain; Brain Mapping; Contrast Media; Dopamine D2 Receptor Antagonists; Humans; Iodine Radioisotopes; Isoxazoles; Male; Piperidines; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	1993
Antipsychotic medication, D2 dopamine receptor blockade and clinical response: a 123I IBZM SPET (single photon emission tomography) study. Psychological medicine, 1993, Volume: 23, Issue:3 Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Binding, Competitive; Corpus Striatum; Dopamine Antagonists; Female; Humans; Injections, Intravenous; Male; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1993
Stereotypy, schizophrenia and dopamine D2 receptor binding in the basal ganglia. Psychological medicine, 1994, Volume: 24, Issue:2 Topics: Adolescent; Adult; Basal Ganglia; Benzamides; Brain Mapping; Choice Behavior; Dominance, Cerebral; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Stereotyped Behavior; Tomography, Emission-Computed, Single-Photon	1994
D2 dopamine receptor binding in the basal ganglia of antipsychotic-free schizophrenic patients. An 123I-IBZM single photon emission computerised tomography study. The British journal of psychiatry : the journal of mental science, 1994, Volume: 164, Issue:1 Topics: Adolescent; Adult; Basal Ganglia; Benzamides; Corpus Striatum; Dominance, Cerebral; Dopamine D2 Receptor Antagonists; Female; Humans; Iodine Radioisotopes; Limbic System; Male; Middle Aged; Prefrontal Cortex; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	1994
Latent inhibition in drug naive schizophrenics: relationship to duration of illness and dopamine D2 binding using SPET. Schizophrenia research, 1995, Volume: 17, Issue:1 Topics: Adolescent; Adult; Attention; Basal Ganglia; Benzamides; Chronic Disease; Contrast Media; Corpus Striatum; Female; Humans; Male; Neural Inhibition; Neuropsychological Tests; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	1995
[123I]IBZM SPECT for imaging of striatal D2 dopamine receptors in 56 schizophrenic patients taking various neuroleptics. The American journal of psychiatry, 1996, Volume: 153, Issue:2 Topics: Adult; Antipsychotic Agents; Benzamides; Contrast Media; Corpus Striatum; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Frontal Lobe; Humans; Male; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1996
Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects. Proceedings of the National Academy of Sciences of the United States of America, 1996, Aug-20, Volume: 93, Issue:17 Topics: Adult; Amphetamine; Animals; Benzamides; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Humans; Male; Papio; Psychoses, Substance-Induced; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1996
Dopamine D2 receptor occupancy in vivo by the novel atypical antipsychotic olanzapine--a 123I IBZM single photon emission tomography (SPET) study. Psychopharmacology, 1996, Volume: 124, Issue:1-2 Topics: Adult; Antipsychotic Agents; Benzamides; Benzodiazepines; Corpus Striatum; Haloperidol; Humans; Middle Aged; Olanzapine; Pirenzepine; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1996
Individual variation in D2 dopamine receptor occupancy in clozapine-treated patients. The American journal of psychiatry, 1996, Volume: 153, Issue:12 Topics: Adult; Benzamides; Binding, Competitive; Clozapine; Corpus Striatum; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon; Treatment Outcome	1996
Multivariate cluster analysis of dynamic iodine-123 iodobenzamide SPET dopamine D2 receptor images in schizophrenia. European journal of nuclear medicine, 1997, Volume: 24, Issue:2 Topics: Benzamides; Brain; Case-Control Studies; Cluster Analysis; Female; Humans; Iodine Radioisotopes; Male; Multivariate Analysis; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Sex Factors; Tomography, Emission-Computed, Single-Photon	1997
Effect of haloperidol dose on iodine-123-IBZM brain SPECT imaging in schizophrenic patients. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1997, Volume: 38, Issue:2 Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Brain; Cerebellum; Dopamine Antagonists; Dopamine D2 Receptor Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Iodine Radioisotopes; Male; Pyrrolidines; Radionuclide Imaging; Receptors, Dopamine D2; Schizophrenia	1997
Striatal dopamine-2 receptor occupancy in psychotic patients treated with risperidone. Psychiatry research, 1996, Nov-25, Volume: 68, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antipsychotic Agents; Benzamides; Brain Mapping; Dopamine Antagonists; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	1996
SPECT studies of D2 occupancy in low-dose haloperidol treatment. The American journal of psychiatry, 1997, Volume: 154, Issue:5 Topics: Adult; Basal Ganglia; Benzamides; Cerebellum; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Haloperidol; Humans; Male; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	1997
Single photon emission computed tomography imaging of dopaminergic function: presynaptic transporter, postsynaptic receptor, and "intrasynaptic" transmitter. Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42 Topics: Animals; Benzamides; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Parkinson Disease; Presynaptic Terminals; Primates; Pyrrolidines; Receptors, Dopamine; Reference Values; Schizophrenia; Serotonin; Serotonin Plasma Membrane Transport Proteins; Synapses; Tomography, Emission-Computed, Single-Photon	1998
Previous treatment as a confounding variable in studies with novel antipsychotics: two cases of high dopamine-2 receptor occupancy with quetiapine. Psychopharmacology, 1997, Volume: 133, Issue:1 Topics: Adult; Antipsychotic Agents; Benzamides; Confounding Factors, Epidemiologic; Corpus Striatum; Dibenzothiazepines; Humans; Iodine Radioisotopes; Male; Pyrrolidines; Quetiapine Fumarate; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1997
D2 dopamine receptor occupancy: a crossover comparison of risperidone with clozapine therapy in schizophrenic patients. Archives of general psychiatry, 1997, Volume: 54, Issue:10 Topics: Adult; Benzamides; Clozapine; Humans; Iodine Radioisotopes; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia	1997
Gender differences in D2 dopamine receptor binding in drug-naive patients with schizophrenia: an [123I]iodobenzamide single photon emission computed tomography study. Psychiatry research, 1997, Sep-29, Volume: 75, Issue:2 Topics: Adolescent; Adult; Benperidol; Benzamides; Brain Mapping; Corpus Striatum; Dominance, Cerebral; Dopamine Antagonists; Female; Frontal Lobe; Humans; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Sex Factors; Tomography, Emission-Computed, Single-Photon	1997
Haloperidol serum concentrations and D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate. International clinical psychopharmacology, 1997, Volume: 12, Issue:5 Topics: Adult; Aged; Antipsychotic Agents; Benzamides; Brain; Dopamine Antagonists; Female; Haloperidol; Humans; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1997
Sertindole and dopamine D2 receptor occupancy in comparison to risperidone, clozapine and haloperidol - a 123I-IBZM SPECT study. Psychopharmacology, 1998, Volume: 136, Issue:4 Topics: Adult; Antipsychotic Agents; Benzamides; Clozapine; Female; Haloperidol; Humans; Imidazoles; Indoles; Iodine Radioisotopes; Male; Middle Aged; Neostriatum; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1998
Increased striatal dopamine transmission in schizophrenia: confirmation in a second cohort. The American journal of psychiatry, 1998, Volume: 155, Issue:6 Topics: Adult; Amphetamine; Benzamides; Cohort Studies; Corpus Striatum; Dopamine; Female; Humans; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine; Reproducibility of Results; Schizophrenia; Synaptic Transmission; Tomography, Emission-Computed, Single-Photon	1998
Psychomotor slowing, negative symptoms and dopamine receptor availability--an IBZM SPECT study in neuroleptic-treated and drug-free schizophrenic patients. Schizophrenia research, 1998, May-04, Volume: 31, Issue:1 Topics: Acute Disease; Adult; Antipsychotic Agents; Benzamides; Brain; Dopamine Antagonists; Haloperidol; Humans; Middle Aged; Psychomotor Disorders; Pyrrolidines; Reaction Time; Receptors, Dopamine; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1998
Iodine-123-iodobenzamide SPECT assessment of dopamine D2 receptor occupancy in riperidone-treated schizophrenic patients. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1998, Volume: 39, Issue:7 Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Brain; Clozapine; Contrast Media; Dose-Response Relationship, Drug; Female; Haloperidol; Humans; Iodine Radioisotopes; Male; Middle Aged; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1998
[Clinical impact of cerebral dopamine-D2 receptor scintigraphy]. Nuklearmedizin. Nuclear medicine, 1998, Volume: 37, Issue:7 Topics: Benzamides; Brain; Carbon Radioisotopes; Fluorine Radioisotopes; Humans; Iodine Radioisotopes; Mental Disorders; Parkinson Disease; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Substance-Related Disorders; Tissue Distribution; Tomography, Emission-Computed; Tomography, Emission-Computed, Single-Photon	1998
In vivo effects of olanzapine on striatal dopamine D(2)/D(3) receptor binding in schizophrenic patients: an iodine-123 iodobenzamide single-photon emission tomography study. European journal of nuclear medicine, 1999, Volume: 26, Issue:8 Topics: Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Benzodiazepines; Case-Control Studies; Corpus Striatum; Dopamine Antagonists; Female; Humans; Iodine Radioisotopes; Male; Olanzapine; Pirenzepine; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1999
In vivo determination of striatal dopamine D2 receptor occupancy in patients treated with olanzapine. Psychiatry research, 1999, Apr-26, Volume: 90, Issue:2 Topics: Adult; Benzamides; Benzodiazepines; Case-Control Studies; Contrast Media; Corpus Striatum; Dose-Response Relationship, Drug; Female; Humans; Male; Olanzapine; Parkinson Disease, Secondary; Pirenzepine; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Tomography, Emission-Computed, Single-Photon	1999
Occupancy of striatal D(2)-like dopamine receptors after treatment with the sigma ligand EMD 57445, a putative atypical antipsychotic. Psychopharmacology, 1999, Sep-01, Volume: 146, Issue:1 Topics: Adult; Antipsychotic Agents; Benzamides; Blood-Brain Barrier; Corpus Striatum; Female; Humans; Male; Middle Aged; Oxazoles; Piperidines; Pyrimidines; Pyrrolidines; Receptors, Dopamine D2; Receptors, sigma; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1999
Dopamine D2 receptor occupancy measured by single photon emission computed tomography with 123I-Iodobenzamide in chronic schizophrenia. Psychiatry research, 1994, Volume: 55, Issue:2 Topics: Adult; Antipsychotic Agents; Basal Ganglia; Benzamides; Chronic Disease; Contrast Media; Dopamine Antagonists; Female; Frontal Lobe; Humans; Iodine Radioisotopes; Male; Middle Aged; Prognosis; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1994
Subjective experience and striatal dopamine D(2) receptor occupancy in patients with schizophrenia stabilized by olanzapine or risperidone. The American journal of psychiatry, 2000, Volume: 157, Issue:6 Topics: Adolescent; Adult; Antipsychotic Agents; Basal Ganglia Diseases; Benzamides; Benzodiazepines; Corpus Striatum; Female; Health Status; Humans; Iodine Radioisotopes; Male; Olanzapine; Pirenzepine; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	2000
Schizophrenia: more dopamine, more D2 receptors. Proceedings of the National Academy of Sciences of the United States of America, 2000, Jul-05, Volume: 97, Issue:14 Topics: Benzamides; Dopamine; Dopamine Antagonists; Models, Biological; Psychotic Disorders; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia	2000
Dopamine and schizophrenia--proof at last? Lancet (London, England), 2000, Sep-16, Volume: 356, Issue:9234 Topics: Antipsychotic Agents; Benzamides; Dopamine; Dopamine Antagonists; Humans; Pyrrolidines; Receptors, Dopamine; Schizophrenia; Up-Regulation	2000
The variable number of tandem repeats polymorphism of the dopamine transporter gene is not associated with significant change in dopamine transporter phenotype in humans. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2001, Volume: 24, Issue:5 Topics: Adult; Amphetamine; Attention Deficit Disorder with Hyperactivity; Benzamides; Carrier Proteins; Cocaine; Cocaine-Related Disorders; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Genotype; Humans; Iodine Radioisotopes; Membrane Glycoproteins; Membrane Transport Proteins; Minisatellite Repeats; Neostriatum; Nerve Tissue Proteins; Phenotype; Polymorphism, Genetic; Psychotic Disorders; Pyrrolidines; Radiopharmaceuticals; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2001
Dopamine D(2) receptor blockade in schizophrenia. The American journal of psychiatry, 2001, Volume: 158, Issue:6 Topics: Antipsychotic Agents; Benzamides; Brief Psychiatric Rating Scale; Depression; Dopamine D2 Receptor Antagonists; Humans; Iodine Radioisotopes; Pyrrolidines; Receptors, Dopamine D2; Risperidone; Schizophrenia; Tomography, Emission-Computed, Single-Photon	2001
Clozapine, single photon emission tomography, and the D2 dopamine receptor blockade hypothesis of schizophrenia. Lancet (London, England), 1992, Jul-25, Volume: 340, Issue:8813 Topics: Adult; Antipsychotic Agents; Benzamides; Brain; Clozapine; Computers; Female; Humans; Male; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine; Receptors, Dopamine D2; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1992
Single photon emission tomography assessment of cerebral dopamine D2 receptor blockade in schizophrenia. Biological psychiatry, 1992, Aug-01, Volume: 32, Issue:3 Topics: Adult; Aged; Antipsychotic Agents; Basal Ganglia; Benzamides; Brain; Cerebellum; Contrast Media; Humans; Iodine Radioisotopes; Male; Middle Aged; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine D2; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	1992
SPECT technique for visualization of cerebral dopamine D2 receptors. The American journal of psychiatry, 1991, Volume: 148, Issue:11 Topics: Antipsychotic Agents; Benzamides; Brain; Brain Chemistry; Female; Humans; Male; Psychiatric Status Rating Scales; Pyrrolidines; Receptors, Dopamine; Schizophrenia; Schizophrenic Psychology; Tomography, Emission-Computed, Single-Photon	1991
In vivo characterisation of 3-iodo-6-methoxybenzamide 123I in humans. European journal of nuclear medicine, 1990, Volume: 16, Issue:11 Topics: Adult; Alzheimer Disease; Benzamides; Brain; Humans; Iodine Radioisotopes; Male; Pyrrolidines; Receptors, Dopamine; Schizophrenia; Tomography, Emission-Computed, Single-Photon	1990