3-hydroxykynurenine has been researched along with Pregnancy in 8 studies
3-hydroxykynurenine: RN given refers to cpd without isomeric designation
3-hydroxykynurenine : A hydroxykynurenine that is kynurenine substituted by a hydroxy group at position 3.
hydroxykynurenine : A hydroxy-amino acid that is kynurenine substituted by a single hydroxy group at unspecified position. A "closed" class.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Several studies suggest a pathophysiologically relevant association between increased brain levels of the neuroinhibitory tryptophan metabolite kynurenic acid and cognitive dysfunctions in people with schizophrenia." | 7.88 | Maternal genotype determines kynurenic acid levels in the fetal brain: Implications for the pathophysiology of schizophrenia. ( Beggiato, S; Giorgini, F; Notarangelo, FM; Sathyasaikumar, KV; Schwarcz, R, 2018) |
| " As KP metabolism during pregnancy is still insufficiently understood, we designed this study to examine the de novo synthesis of KYNA and 3-hydroxykynurenine (3-HK), an alternative biologically active product of kynurenine degradation, in tissue slices obtained from pregnant mice on gestational day (GD) 18." | 3.91 | Assessment of Prenatal Kynurenine Metabolism Using Tissue Slices: Focus on the Neosynthesis of Kynurenic Acid in Mice. ( Beggiato, S; Notarangelo, FM; Schwarcz, R, 2019) |
| "Several studies suggest a pathophysiologically relevant association between increased brain levels of the neuroinhibitory tryptophan metabolite kynurenic acid and cognitive dysfunctions in people with schizophrenia." | 3.88 | Maternal genotype determines kynurenic acid levels in the fetal brain: Implications for the pathophysiology of schizophrenia. ( Beggiato, S; Giorgini, F; Notarangelo, FM; Sathyasaikumar, KV; Schwarcz, R, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goeden, N | 1 |
| Notarangelo, FM | 3 |
| Pocivavsek, A | 2 |
| Beggiato, S | 3 |
| Bonnin, A | 1 |
| Schwarcz, R | 6 |
| Sathyasaikumar, KV | 1 |
| Giorgini, F | 1 |
| Wu, HQ | 1 |
| Elmer, GI | 1 |
| Bruno, JP | 1 |
| Ceresoli-Borroni, G | 2 |
| Guidetti, P | 1 |
| Amori, L | 1 |
| Pellicciari, R | 1 |
| Fujii, K | 1 |
| Watanabe, M | 1 |
| Guilarte, TR | 1 |
| Wagner, HN | 1 |
8 other studies available for 3-hydroxykynurenine and Pregnancy
| Article | Year |
|---|---|
Prenatal Dynamics of Kynurenine Pathway Metabolism in Mice: Focus on Kynurenic Acid.
Topics: Animals; Brain; Female; Kynurenic Acid; Kynurenine; Mice; Placenta; Pregnancy; Tryptophan | 2017 |
Maternal genotype determines kynurenic acid levels in the fetal brain: Implications for the pathophysiology of schizophrenia.
Topics: Animals; Brain; Cognitive Dysfunction; Female; Genotype; Kynurenic Acid; Kynurenine; Kynurenine 3-Mo | 2018 |
Assessment of Prenatal Kynurenine Metabolism Using Tissue Slices: Focus on the Neosynthesis of Kynurenic Acid in Mice.
Topics: Animals; Brain; Female; Fetus; Kynurenic Acid; Kynurenine; Liver; Mice; Mice, Knockout; Organ Cultur | 2019 |
Pre- and postnatal exposure to kynurenine causes cognitive deficits in adulthood.
Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Chromatography, High Pressure Liquid; | 2012 |
Perinatal kynurenine 3-hydroxylase inhibition in rodents: pathophysiological implications.
Topics: Animals; Animals, Newborn; Brain Chemistry; Cyclopropanes; Deoxycholic Acid; Drug Administration Sch | 2007 |
Comparative study of tumorigenicity in mice administered transplacentally or neonatally with metabolites of tryptophan and its related compounds.
Topics: 3-Hydroxyanthranilic Acid; Adenoma; Animals; Animals, Newborn; Carcinogens; Carcinoma, Hepatocellula | 1980 |
Neonatal asphyxia in rats: acute effects on cerebral kynurenine metabolism.
Topics: Animals; Animals, Newborn; Asphyxia Neonatorum; Behavior, Animal; Brain; Female; Humans; Infant, New | 2001 |
3-Hydroxykynurenine as a possible mechanism of epileptic seizures associated with neonatal vitamin B6 deficiency.
Topics: Animals; Animals, Newborn; Brain; Epilepsy; Female; Kynurenine; Pregnancy; Rats; Synaptic Transmissi | 1986 |