3-hydroxykynurenine has been researched along with Allergic Encephalomyelitis in 1 studies
3-hydroxykynurenine: RN given refers to cpd without isomeric designation
3-hydroxykynurenine : A hydroxykynurenine that is kynurenine substituted by a hydroxy group at position 3.
hydroxykynurenine : A hydroxy-amino acid that is kynurenine substituted by a single hydroxy group at unspecified position. A "closed" class.
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zarzecki, MS | 1 |
| Cattelan Souza, L | 1 |
| Giacomeli, R | 1 |
| Silva, MRP | 1 |
| Prigol, M | 1 |
| Boeira, SP | 1 |
| Jesse, CR | 1 |
1 other study(ies) available for 3-hydroxykynurenine and Allergic Encephalomyelitis
| Article | Year |
|---|---|
Involvement of Indoleamine-2,3-Dioxygenase and Kynurenine Pathway in Experimental Autoimmune Encephalomyelitis in Mice.
Topics: Animals; Body Weight; Cytokines; Encephalomyelitis, Autoimmune, Experimental; Enzyme Inhibitors; Female; Gene Expression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenine; Kynurenine 3-Monooxygenase; Mice, Inbred C57BL; Myelin-Oligodendrocyte Glycoprotein; Oximes; Peptide Fragments; Quinolinic Acid; Sulfonamides; Tryptophan | 2020 |