Page last updated: 2024-10-15

3-hydroxyisobutyric acid and Insulin Resistance

3-hydroxyisobutyric acid has been researched along with Insulin Resistance in 5 studies

3-hydroxyisobutyric acid: RN given refers to cpd without isomeric designation
3-hydroxyisobutyric acid : A 4-carbon, branched hydroxy fatty acid and intermediate in the metabolism of valine.

Insulin Resistance: Diminished effectiveness of INSULIN in lowering blood sugar levels: requiring the use of 200 units or more of insulin per day to prevent HYPERGLYCEMIA or KETOSIS.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (60.00)24.3611
2020's2 (40.00)2.80

Authors

AuthorsStudies
Nilsen, MS1
Jersin, RÅ1
Ulvik, A1
Madsen, A1
McCann, A1
Svensson, PA1
Svensson, MK1
Nedrebø, BG1
Gudbrandsen, OA1
Tell, GS1
Kahn, CR1
Ueland, PM1
Mellgren, G1
Dankel, SN2
Bjune, MS1
Lindquist, C1
Hallvardsdotter Stafsnes, M1
Bjørndal, B1
Bruheim, P1
Aloysius, TA1
Nygård, O1
Skorve, J1
Madsen, L1
Berge, RK1
Haufe, S1
Engeli, S1
Kaminski, J1
Witt, H1
Rein, D1
Kamlage, B1
Utz, W1
Fuhrmann, JC1
Haas, V1
Mähler, A1
Schulz-Menger, J1
Luft, FC1
Boschmann, M1
Jordan, J1
Andersson-Hall, U1
Gustavsson, C1
Pedersen, A1
Malmodin, D1
Joelsson, L1
Holmäng, A1
Lyon, ES1
Rivera, ME1
Johnson, MA1
Sunderland, KL1
Vaughan, RA1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Parallel Group Comparison on the Influence of a Low Carbohydrate and a Low Fat Hypocaloric 6 Months Diet on Body Weight Reduction, Metabolic and Cardiovascular Variables in Obese Healthy Women and Men.[NCT00956566]170 participants (Actual)Interventional2007-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for 3-hydroxyisobutyric acid and Insulin Resistance

ArticleYear
Branched-chain amino acid catabolism rather than amino acids plasma concentrations is associated with diet-induced changes in insulin resistance in overweight to obese individuals.
    Nutrition, metabolism, and cardiovascular diseases : NMCD, 2017, Volume: 27, Issue:10

    Topics: Adipose Tissue; Adult; Amino Acids, Branched-Chain; Biomarkers; Blood Glucose; Caloric Restriction;

2017

Other Studies

4 other studies available for 3-hydroxyisobutyric acid and Insulin Resistance

ArticleYear
3-Hydroxyisobutyrate, A Strong Marker of Insulin Resistance in Type 2 Diabetes and Obesity That Modulates White and Brown Adipocyte Metabolism.
    Diabetes, 2020, Volume: 69, Issue:9

    Topics: Adipocytes, Brown; Adipocytes, White; Amino Acids, Branched-Chain; Biomarkers; Body Composition; Cel

2020
Plasma 3-hydroxyisobutyrate (3-HIB) and methylmalonic acid (MMA) are markers of hepatic mitochondrial fatty acid oxidation in male Wistar rats.
    Biochimica et biophysica acta. Molecular and cell biology of lipids, 2021, Volume: 1866, Issue:4

    Topics: Animals; Fatty Acids; Hydroxybutyrates; Insulin Resistance; Male; Methylmalonic Acid; Mitochondria,

2021
Higher Concentrations of BCAAs and 3-HIB Are Associated with Insulin Resistance in the Transition from Gestational Diabetes to Type 2 Diabetes.
    Journal of diabetes research, 2018, Volume: 2018

    Topics: Adiponectin; Adult; Amino Acids, Branched-Chain; Blood Glucose; Body Mass Index; Diabetes Mellitus,

2018
Actions of chronic physiological 3-hydroxyisobuterate treatment on mitochondrial metabolism and insulin signaling in myotubes.
    Nutrition research (New York, N.Y.), 2019, Volume: 66

    Topics: Amino Acids, Branched-Chain; Animals; Cell Line; Dose-Response Relationship, Drug; Gene Expression;

2019