Page last updated: 2024-09-05

3-hydroxyglutaric acid and Nerve Degeneration

3-hydroxyglutaric acid has been researched along with Nerve Degeneration in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (16.67)	18.2507
2000's	5 (83.33)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Hoffmann, GF; Koeller, DM; Kölker, S; Okun, JG	1
Christensen, E; Kristensen, AS; Lund, AM; Lund, TM; Schousboe, A	1
Freudenberg, F; Lukacs, Z; Ullrich, K	1
Bührer, C; Gerstner, B; Gratopp, A; Marcinkowski, M; Obladen, M; Sifringer, M	1
Christensen, E; Deufel, T; Falter, C; Fautek, JD; Fingerhut, R; Flott-Rahmel, B; Jakobs, C; Ludolph, A; Musshoff, U; Schluff, P; Ullrich, K	1
Bjugstad, KB; Freed, CR; Goodman, S; Zawada, WM	1

Reviews

1 review(s) available for 3-hydroxyglutaric acid and Nerve Degeneration

Article	Year
Pathomechanisms of neurodegeneration in glutaryl-CoA dehydrogenase deficiency. Annals of neurology, 2004, Volume: 55, Issue:1 Topics: Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child, Preschool; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Infant; Models, Neurological; Nerve Degeneration; Oxidoreductases Acting on CH-CH Group Donors	2004

Other Studies

5 other study(ies) available for 3-hydroxyglutaric acid and Nerve Degeneration

Article	Year
On the neurotoxicity of glutaric, 3-hydroxyglutaric, and trans-glutaconic acids in glutaric acidemia type 1. Journal of neuroscience research, 2004, Jul-01, Volume: 77, Issue:1 Topics: Animals; Brain Diseases, Metabolic, Inborn; Cell Death; Cells, Cultured; Cerebral Cortex; Corpus Striatum; Fetus; Glutarates; Glutaryl-CoA Dehydrogenase; Membrane Potentials; Mice; Nerve Degeneration; Neurons; Neurotoxins; Oocytes; Oxidoreductases Acting on CH-CH Group Donors; Rats; Receptors, N-Methyl-D-Aspartate; Xenopus	2004
3-Hydroxyglutaric acid fails to affect the viability of primary neuronal rat cells. Neurobiology of disease, 2004, Volume: 16, Issue:3 Topics: Acids; Animals; Apoptosis; Blotting, Western; Cell Survival; Cells, Cultured; Glutarates; Glutaryl-CoA Dehydrogenase; Nerve Degeneration; Neurons; Oxidoreductases Acting on CH-CH Group Donors; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate	2004
Glutaric acid and its metabolites cause apoptosis in immature oligodendrocytes: a novel mechanism of white matter degeneration in glutaryl-CoA dehydrogenase deficiency. Pediatric research, 2005, Volume: 57, Issue:6 Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Base Sequence; Brain Diseases, Metabolic, Inborn; Caspase Inhibitors; Cell Differentiation; Cell Line; Glutarates; Glutaryl-CoA Dehydrogenase; Humans; Nerve Degeneration; Oligodendroglia; Oxidoreductases Acting on CH-CH Group Donors; Rats; Receptors, Glutamate; RNA, Messenger	2005
Nerve cell lesions caused by 3-hydroxyglutaric acid: a possible mechanism for neurodegeneration in glutaric acidaemia I. Journal of inherited metabolic disease, 1997, Volume: 20, Issue:3 Topics: Adenosine Triphosphate; Amino Acid Metabolism, Inborn Errors; Animals; Electrophysiology; Glutarates; Hippocampus; Nerve Degeneration; Nervous System Diseases; Neurons; Organ Culture Techniques; Rats	1997
IGF-1 and bFGF reduce glutaric acid and 3-hydroxyglutaric acid toxicity in striatal cultures. Journal of inherited metabolic disease, 2001, Volume: 24, Issue:6 Topics: Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Excitatory Amino Acid Antagonists; Fibroblast Growth Factor 2; Glutarates; Growth Substances; Hydrogen-Ion Concentration; Immunohistochemistry; Insulin; Insulin-Like Growth Factor I; Male; Neostriatum; Nerve Degeneration; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Tryptophan	2001