3-hydroxyflavone has been researched along with Malignant Melanoma in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 14 (87.50) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Banang-Mbeumi, S; Basnet, P; Boateng, ST; Chamcheu, JC; Chamcheu, RN; Chauvin, I; Fotie, J; Hill, RA; Kousoulas, KG; Ladu, F; Murru, S; Nagalo, BM; Roy, T; Sechi, M; Singh, PK; Spiegelman, VS; Walker, AL | 1 |
| Chen, YM; Peng, Y; Sun, HY; Yue, JQ; Zhong, ZJ; Zhou, DZ | 1 |
| Chien, HW; Hsieh, YH; Hu, DN; Lin, HW; Wang, K; Yang, SF; Yang, WE | 1 |
| Afolabi, SO; Chiu, SY; Joshi, DC; Lall, RK; Mukhtar, H; Sechi, M; Singh, A; Syed, DN | 1 |
| Afaq, F; Athar, M; Ballestas, ME; Elmets, CA; Katiyar, SK; Pal, HC; Sharma, S; Strickland, LR | 1 |
| Adhami, VM; Chamcheu, JC; Khan, MI; Lall, RK; Mukhtar, H; Sechi, M; Syed, DN | 1 |
| Chen, H; Li, M; Liu, B; Liu, J; Zeng, G; Zhang, Q; Zhu, R | 1 |
| Im, SJ; Kim, JH; Kim, MY | 1 |
| Deng, W; Guo, W; Qiu, H; Tang, R; Wang, J; Xiao, Y; Yi, C; Yu, W; Yu, Z; Yuan, Y; Zhang, Y | 1 |
| Chamcheu, JC; Haidar, O; Lall, RK; Mukhtar, H; Syed, DN | 1 |
| Afaq, F; Agarwal, J; Athar, M; Baxter, RD; Elmets, CA; Hunt, KM; Pal, HC | 1 |
| Afaq, F; Athar, M; Diamond, AC; Elmets, CA; Kappes, JC; Katiyar, SK; Pal, HC; Strickland, LR | 1 |
| Czyz, M; Gajos-Michniewicz, A | 1 |
| Afaq, F; Ahmad, A; Johnson, JJ; Maddodi, N; Mukhtar, H; Sarfaraz, S; Setaluri, V; Syed, DN | 1 |
| Arbiser, JL; Fisher, DE | 1 |
| Bobet, R; Carilla, J; Cascante, M; Centelles, JJ; García, MT; Matito, C; Sort, X; Torres, JL; Varela, B | 1 |
1 review(s) available for 3-hydroxyflavone and Malignant Melanoma
| Article | Year |
|---|---|
Modulation of WNT/β-catenin pathway in melanoma by biologically active components derived from plants.
Topics: Animals; Clinical Trials as Topic; Flavonoids; Flavonols; Humans; Melanoma; Pentacyclic Triterpenes; Phytochemicals; Quinazolines; Silymarin; Wnt Signaling Pathway | 2016 |
15 other study(ies) available for 3-hydroxyflavone and Malignant Melanoma
| Article | Year |
|---|---|
Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers.
Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Cell Survival; Cyclin-Dependent Kinase 2; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Flavonols; Humans; Melanoma; Molecular Docking Simulation; Molecular Structure; Proto-Oncogene Proteins c-kit; Skin Neoplasms; Structure-Activity Relationship; TOR Serine-Threonine Kinases; Tumor Cells, Cultured | 2021 |
Dihydromyricetin induces apoptosis and cytoprotective autophagy through ROS-NF-κB signalling in human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Cytoprotection; Drug Screening Assays, Antitumor; Flavonols; Humans; Melanoma; NF-kappa B; Reactive Oxygen Species; Signal Transduction; Skin Neoplasms | 2017 |
Fisetin induces apoptosis through mitochondrial apoptosis pathway in human uveal melanoma cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cytochromes c; Flavonoids; Flavonols; Humans; Melanoma; Membrane Potential, Mitochondrial; Mitochondria; Proto-Oncogene Proteins c-bcl-2; Uveal Neoplasms | 2018 |
Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models.
Topics: Antineoplastic Agents; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; Epithelial-Mesenchymal Transition; Flavonoids; Flavonols; Humans; MAP Kinase Signaling System; Melanoma; Phosphorylation; Ribosomal Protein S6 Kinases, 90-kDa; Signal Transduction; Transcription, Genetic; Y-Box-Binding Protein 1 | 2018 |
Fisetin inhibits human melanoma cell invasion through promotion of mesenchymal to epithelial transition and by targeting MAPK and NFκB signaling pathways.
Topics: Antigens, CD; Antineoplastic Agents, Phytogenic; Cadherins; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Transdifferentiation; Drug Screening Assays, Antitumor; Flavonoids; Flavonols; Humans; MAP Kinase Signaling System; Melanoma; Neoplasm Invasiveness; NF-kappa B; Phosphorylation; Protein Processing, Post-Translational; Protein Transport; Vimentin | 2014 |
Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Computer Simulation; Flavonoids; Flavonols; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Models, Biological; Protein Binding; Ribosomal Protein S6 Kinases, 70-kDa; TOR Serine-Threonine Kinases | 2014 |
Dihydromyricetin induces cell cycle arrest and apoptosis in melanoma SK-MEL-28 cells.
Topics: Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Flavonols; Gene Expression Regulation, Neoplastic; Humans; Melanoma; Neoplasm Proteins | 2014 |
Evaluation of bioactive components and antioxidant and anticancer properties of citrus wastes generated during bioethanol production.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Biofuels; Carcinoma; Cell Line, Tumor; Cell Survival; Citrus; Colonic Neoplasms; Dose-Response Relationship, Drug; Ethanol; Flavanones; Flavonols; Humans; Melanoma; Solid Waste | 2014 |
Melatonin enhances the anti-tumor effect of fisetin by inhibiting COX-2/iNOS and NF-κB/p300 signaling pathways.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Drug Synergism; E1A-Associated p300 Protein; Flavonoids; Flavonols; Humans; Melanoma; Melatonin; NF-kappa B; Nitric Oxide Synthase Type II; Signal Transduction | 2014 |
Involvement of ER stress and activation of apoptotic pathways in fisetin induced cytotoxicity in human melanoma.
Topics: Adenosine Triphosphate; AMP-Activated Protein Kinases; Antineoplastic Agents, Phytogenic; Apoptosis; Autophagy; Caspase 3; Cell Line, Tumor; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Flavonoids; Flavonols; Humans; Melanoma; Nitric Oxide; Reactive Oxygen Species; Signal Transduction | 2014 |
Fisetin, a phytochemical, potentiates sorafenib-induced apoptosis and abrogates tumor growth in athymic nude mice implanted with BRAF-mutated melanoma cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Caspase 3; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Female; Flavonoids; Flavonols; Humans; Immunohistochemistry; Melanoma; Mice, Nude; Mitogen-Activated Protein Kinases; Mutation; Niacinamide; Phenylurea Compounds; Phosphatidylinositol 3-Kinases; Poly(ADP-ribose) Polymerases; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Sorafenib; Tumor Burden; Xenograft Model Antitumor Assays | 2015 |
Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cadherins; Cell Line, Tumor; Cell Movement; Cells, Cultured; Drug Synergism; Epithelial-Mesenchymal Transition; Female; Flavonoids; Flavonols; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melanoma; Mice, Nude; Mutation; Neoplasm Invasiveness; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins B-raf; Sorafenib; Tumor Burden; Xenograft Model Antitumor Assays | 2016 |
Inhibition of human melanoma cell growth by the dietary flavonoid fisetin is associated with disruption of Wnt/β-catenin signaling and decreased Mitf levels.
Topics: Animals; Antineoplastic Agents; beta Catenin; beta-Transducin Repeat-Containing Proteins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Female; Flavonoids; Flavonols; G1 Phase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatocyte Nuclear Factor 1-beta; Humans; Melanoma; Mice; Microphthalmia-Associated Transcription Factor; Signal Transduction; Wnt Proteins | 2011 |
Fisetin: a natural fist against melanoma?
Topics: Antineoplastic Agents; Flavonoids; Flavonols; Humans; Melanoma; Microphthalmia-Associated Transcription Factor; Proto-Oncogene Proteins B-raf | 2011 |
Valorization of grape (Vitis vinifera) byproducts. Antioxidant and biological properties of polyphenolic fractions differing in procyanidin composition and flavonol content.
Topics: Antioxidants; Biflavonoids; Catechin; Cell Division; Chemical Fractionation; Chemical Phenomena; Chemistry, Physical; Cysteamine; Emulsions; Flavonoids; Flavonols; Free Radical Scavengers; Glycosylation; Humans; Lipid Peroxidation; Melanoma; Phenols; Plant Oils; Polymers; Proanthocyanidins; Tumor Cells, Cultured; Vitis | 2002 |