Page last updated: 2024-08-21

3-hydroxyflavone and Lung Neoplasms

3-hydroxyflavone has been researched along with Lung Neoplasms in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (16.67)29.6817
2010's15 (62.50)24.3611
2020's5 (20.83)2.80

Authors

AuthorsStudies
Chinnasamy, A; Devadoss, D; Ramar, M1
Patel, DK1
Eguchi, H; Endo, S; Ikari, A; Kimura, R; Matsunaga, H; Matsunaga, T; Yoshino, Y1
Ali, M; Avgenikos, M; Caburet, J; de Meester, JSB; Dheeraj, A; Kaschula, CH; Mishra, D; Sabarwal, A; Singh, RP; Stander, S; van Otterlo, WAL; van Rooyen, JC1
Li, Y; Liu, T; Shi, Z; Sun, J; Tian, G1
Alsheikh, HA; Elhamamsy, AR; Kammerud, SC; Mattheyses, AL; Metge, BJ; Samant, RS; Shevde, LA; Weeks, SE1
Chen, L; Meng, WS; Meng, ZL; Shi, B; Wang, LF1
Fan, KJ; Liu, Y; Tian, XD; Wang, B; Yang, B1
Grzanka, A; Grzanka, D; Hałas-Wiśniewska, M; Klimaszewska-Wiśniewska, A1
Singh, RP; Tabasum, S1
Bishayee, K; Boujedaini, N; Khuda-Bukhsh, AR; Mukherjee, A; Sikdar, S1
Choi, YW; Manikandan, R; Ramesh, B; Ravichandran, N; Suresh, G; Vijaiyan Siva, G1
Hyun, JW; Kang, KA; Piao, MJ1
Khan, N; Mukhtar, H1
Afaq, F; Athar, M; Diamond, AC; Elmets, CA; Kappes, JC; Katiyar, SK; Pal, HC; Strickland, LR1
Chae, S; Hyun, JW; Kang, KA; Kwon, TK; Madduma Hewage, SR; Oh, MC; Piao, MJ; Ryu, YS1
Chang, JH; Chien, MH; Chow, JM; Chung, CL; Hung, WY; Kao, SJ; Lee, WJ1
Chao, CH; Chiang, TA; Lee, XY; Liao, YC; Shih, YW1
Ramesh, B; Ravichandran, N; Siva, GV; Suresh, G1
Hirayama, M; Kawakami, K; Konishi, T; Nakajima, Y; Nishida, H; Tatewaki, N1
Afaq, F; Khan, N; Khusro, FH; Mukhtar, H; Mustafa Adhami, V; Suh, Y1
Dwyer, J; Katsouyanni, K; Lagiou, A; Lagiou, P; Peterson, J; Samoli, E; Trichopoulos, D1
Mursu, J; Nurmi, T; Pukkala, E; Salonen, JT; Tuomainen, TP; Voutilainen, S1
Barraj, LM; Cutler, GJ; Harnack, LJ; Jacobs, DR; Mink, PJ; Nettleton, JA; Robien, K; Ross, JA; Scrafford, CG1

Reviews

1 review(s) available for 3-hydroxyflavone and Lung Neoplasms

ArticleYear
Dietary agents for prevention and treatment of lung cancer.
    Cancer letters, 2015, Apr-10, Volume: 359, Issue:2

    Topics: Adenocarcinoma; Administration, Oral; Animals; Anticarcinogenic Agents; Antineoplastic Agents, Phytogenic; Catechin; Curcumin; Flavonoids; Flavonols; Humans; Indoles; Isothiocyanates; Lung Neoplasms; Plant Extracts; Polyphenols

2015

Other Studies

23 other study(ies) available for 3-hydroxyflavone and Lung Neoplasms

ArticleYear
Galangin, a dietary flavonol inhibits tumor initiation during experimental pulmonary tumorigenesis by modulating xenobiotic enzymes and antioxidant status.
    Archives of pharmacal research, 2018, Volume: 41, Issue:3

    Topics: Animals; Antioxidants; Carcinogenesis; Flavonoids; Lung Neoplasms; Male; Mice; Xenobiotics

2018
Medicinal Importance, Pharmacological Activities, and Analytical Aspects of Engeletin in Medicine: Therapeutic Benefit Through Scientific Data Analysis.
    Endocrine, metabolic & immune disorders drug targets, 2023, Volume: 23, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Endometritis; Female; Flavonols; Humans; Lung Neoplasms; Medicine, Traditional; Mice

2023
Increase in Anticancer Drug-Induced Toxicity by Fisetin in Lung Adenocarcinoma A549 Spheroid Cells Mediated by the Reduction of Claudin-2 Expression.
    International journal of molecular sciences, 2022, Jul-07, Volume: 23, Issue:14

    Topics: A549 Cells; Adenocarcinoma of Lung; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Claudin-2; Flavonoids; Flavonols; Humans; Hypoxia; Lung Neoplasms; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Tumor Microenvironment

2022
A novel 4'-brominated derivative of fisetin induces cell cycle arrest and apoptosis and inhibits EGFR/ERK1/2/STAT3 pathways in non-small-cell lung cancer without any adverse effects in mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:12

    Topics: Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; ErbB Receptors; Flavonoids; Flavonols; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mice; STAT3 Transcription Factor

2022
Engeletin suppresses lung cancer progression by inducing apoptotic cell death through modulating the XIAP signaling pathway: A molecular mechanism involving ER stress.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2020, Volume: 128

    Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Apoptosis Regulatory Proteins; Disease Progression; Endoplasmic Reticulum Stress; Flavonols; Gene Expression Regulation, Neoplastic; Glycosides; Humans; Lung Neoplasms; Male; Mice; Mitochondria; Mitochondrial Proteins; Signal Transduction; Transcription Factor CHOP; Tumor Burden; X-Linked Inhibitor of Apoptosis Protein; Xenograft Model Antitumor Assays

2020
Novel role of the dietary flavonoid fisetin in suppressing rRNA biogenesis.
    Laboratory investigation; a journal of technical methods and pathology, 2021, Volume: 101, Issue:11

    Topics: Animals; Cell Line, Tumor; Cell Nucleolus; Drug Screening Assays, Antitumor; Drug Synergism; Flavones; Flavonols; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 4 or More Rings; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mice; RNA Polymerase I; RNA, Ribosomal; Triple Negative Breast Neoplasms

2021
Carnosic acid and fisetin combination therapy enhances inhibition of lung cancer through apoptosis induction.
    International journal of oncology, 2017, Volume: 50, Issue:6

    Topics: Abietanes; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 3; Cell Line, Tumor; Flavonoids; Flavonols; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mice; Signal Transduction; Xenograft Model Antitumor Assays

2017
Inhibition of human lung cancer proliferation through targeting stromal fibroblasts by dihydromyricetin.
    Molecular medicine reports, 2017, Volume: 16, Issue:6

    Topics: Antineoplastic Agents; Cancer-Associated Fibroblasts; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Flavonols; Humans; Lung Neoplasms; MAP Kinase Signaling System; Platelet-Derived Growth Factor; Receptors, Platelet-Derived Growth Factor; Stromal Cells

2017
Evaluation of Anti-Metastatic Potential of the Combination of Fisetin with Paclitaxel on A549 Non-Small Cell Lung Cancer Cells.
    International journal of molecular sciences, 2018, Feb-27, Volume: 19, Issue:3

    Topics: A549 Cells; Actins; Antineoplastic Agents; Apoptosis; Biomarkers; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Synergism; Flavonoids; Flavonols; Gene Expression Profiling; Humans; Lung Neoplasms; Neoplasm Metastasis; Paclitaxel; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; TOR Serine-Threonine Kinases; Vimentin

2018
Fisetin suppresses migration, invasion and stem-cell-like phenotype of human non-small cell lung carcinoma cells via attenuation of epithelial to mesenchymal transition.
    Chemico-biological interactions, 2019, Apr-25, Volume: 303

    Topics: AC133 Antigen; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Movement; Drug Synergism; Epithelial-Mesenchymal Transition; Erlotinib Hydrochloride; Flavonoids; Flavonols; Humans; Hyaluronan Receptors; Lung Neoplasms; Neoplasm Invasiveness; Phenotype; Stem Cells

2019
Flavonol isolated from ethanolic leaf extract of Thuja occidentalis arrests the cell cycle at G2-M and induces ROS-independent apoptosis in A549 cells, targeting nuclear DNA.
    Cell proliferation, 2014, Volume: 47, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell Division; Cell Survival; Disease Models, Animal; DNA, Neoplasm; Dose-Response Relationship, Drug; Flavonols; G2 Phase; Humans; Lung Neoplasms; Mice; Plant Extracts; Plant Leaves; Reactive Oxygen Species; Thuja

2014
Fisetin modulates mitochondrial enzymes and apoptotic signals in benzo(a)pyrene-induced lung cancer.
    Molecular and cellular biochemistry, 2014, Volume: 390, Issue:1-2

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Apoptosis Regulatory Proteins; Benzo(a)pyrene; Flavonoids; Flavonols; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Lipid Peroxidation; Lung Neoplasms; Mice; Mitochondria; Oxidative Stress; Signal Transduction

2014
Fisetin induces apoptosis in human nonsmall lung cancer cells via a mitochondria-mediated pathway.
    In vitro cellular & developmental biology. Animal, 2015, Volume: 51, Issue:3

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Caspases; Cell Line, Tumor; Cell Survival; Flavonoids; Flavonols; Humans; Intracellular Space; Lung Neoplasms; Mitochondria; Reactive Oxygen Species; Signal Transduction

2015
Fisetin, a dietary flavonoid, augments the anti-invasive and anti-metastatic potential of sorafenib in melanoma.
    Oncotarget, 2016, Jan-12, Volume: 7, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Cadherins; Cell Line, Tumor; Cell Movement; Cells, Cultured; Drug Synergism; Epithelial-Mesenchymal Transition; Female; Flavonoids; Flavonols; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Melanoma; Mice, Nude; Mutation; Neoplasm Invasiveness; Niacinamide; Phenylurea Compounds; Proto-Oncogene Proteins B-raf; Sorafenib; Tumor Burden; Xenograft Model Antitumor Assays

2016
Fisetin induces apoptosis and endoplasmic reticulum stress in human non-small cell lung cancer through inhibition of the MAPK signaling pathway.
    Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine, 2016, Volume: 37, Issue:7

    Topics: Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Death; Endoplasmic Reticulum; Endoplasmic Reticulum Stress; Flavonoids; Flavonols; Humans; Lung Neoplasms; Mitochondria; Mitogen-Activated Protein Kinases; Phosphorylation; Reactive Oxygen Species; Signal Transduction

2016
Suppression of reactive oxygen species-mediated ERK and JNK activation sensitizes dihydromyricetin-induced mitochondrial apoptosis in human non-small cell lung cancer.
    Environmental toxicology, 2017, Volume: 32, Issue:4

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Survival; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Flavonols; Humans; JNK Mitogen-Activated Protein Kinases; Lung Neoplasms; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Protein Kinase Inhibitors; Reactive Oxygen Species

2017
Involvement of the ERK signaling pathway in fisetin reduces invasion and migration in the human lung cancer cell line A549.
    Journal of agricultural and food chemistry, 2009, Oct-14, Volume: 57, Issue:19

    Topics: Anticarcinogenic Agents; Antineoplastic Agents; Cell Adhesion; Cell Line, Tumor; Cell Movement; Down-Regulation; Enzyme Inhibitors; Flavonoids; Flavonols; Humans; Lung Neoplasms; Matrix Metalloproteinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Signal Transduction; Urokinase-Type Plasminogen Activator

2009
Fisetin, a novel flavonol attenuates benzo(a)pyrene-induced lung carcinogenesis in Swiss albino mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2011, Volume: 49, Issue:5

    Topics: Analysis of Variance; Animals; Anticarcinogenic Agents; Antineoplastic Agents; Benzo(a)pyrene; Cell Proliferation; Flavonoids; Flavonols; Lipid Peroxidation; Lung; Lung Neoplasms; Male; Mice; Oxidative Stress; Proliferating Cell Nuclear Antigen

2011
Persimmon leaf extract inhibits the ATM activity during DNA damage response induced by Doxorubicin in A549 lung adenocarcinoma cells.
    Bioscience, biotechnology, and biochemistry, 2011, Volume: 75, Issue:4

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Antineoplastic Agents; Ataxia Telangiectasia Mutated Proteins; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Survival; Diospyros; DNA Damage; DNA-Binding Proteins; Doxorubicin; Flavonols; G2 Phase; Humans; Lung Neoplasms; Phosphorylation; Plant Extracts; Plant Leaves; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Signal Transduction; Tumor Suppressor Proteins

2011
Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin.
    International journal of cancer, 2012, Apr-01, Volume: 130, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; AMP-Activated Protein Kinase Kinases; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Eukaryotic Initiation Factor-4E; Flavonoids; Flavonols; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; mTOR Associated Protein, LST8 Homolog; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Protein Kinases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Rapamycin-Insensitive Companion of mTOR Protein; Regulatory-Associated Protein of mTOR; Ribosomal Protein S6 Kinases, 70-kDa; Stem Cells; TOR Serine-Threonine Kinases; Tuberous Sclerosis Complex 2 Protein; Tumor Cells, Cultured; Tumor Suppressor Proteins

2012
Flavonoid intake in relation to lung cancer risk: case-control study among women in Greece.
    Nutrition and cancer, 2004, Volume: 49, Issue:2

    Topics: Case-Control Studies; Female; Flavanones; Flavonoids; Flavonols; Fruit; Greece; Humans; Logistic Models; Lung Neoplasms; Middle Aged; Risk Factors; Smoking; Vegetables

2004
Intake of flavonoids and risk of cancer in Finnish men: The Kuopio Ischaemic Heart Disease Risk Factor Study.
    International journal of cancer, 2008, Aug-01, Volume: 123, Issue:3

    Topics: Anthocyanins; Colorectal Neoplasms; Feeding Behavior; Finland; Flavanones; Flavones; Flavonoids; Flavonols; Follow-Up Studies; Humans; Incidence; Life Style; Lung Neoplasms; Male; Middle Aged; Neoplasms; Odds Ratio; Prospective Studies; Prostatic Neoplasms; Risk Assessment; Risk Factors; Smoking

2008
Dietary flavonoid intake and risk of cancer in postmenopausal women: the Iowa Women's Health Study.
    International journal of cancer, 2008, Aug-01, Volume: 123, Issue:3

    Topics: Aged; Anthocyanins; Breast Neoplasms; Digestive System Neoplasms; Feeding Behavior; Female; Flavanones; Flavones; Flavonoids; Flavonols; Humans; Iowa; Isoflavones; Lung Neoplasms; Middle Aged; Neoplasms; Odds Ratio; Postmenopause; Proanthocyanidins; Prospective Studies; Risk Assessment; Risk Factors; Smoking; Surveys and Questionnaires

2008