Page last updated: 2024-08-21

3-hydroxyflavone and Insulin Resistance

3-hydroxyflavone has been researched along with Insulin Resistance in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (11.54)29.6817
2010's19 (73.08)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Cai, G; Hou, L; Hu, CY; Huang, B; Jiang, F; Jiang, Y; Liu, D; Wang, C; Zheng, W1
Hou, P; Mi, M; Yao, Y; Yi, L; Yue, J; Zhang, Q; Zhou, J1
Chen, G; Dai, X; Feng, J; Ge, C; Hu, LF; Kuang, Q; Lai, L; Li, H; Long, T; Sun, Y; Tan, J; Tang, T; Xiong, M; Xu, M; Yang, Q; Yi, C; Zhan, J; Zhong, S1
Choi, JY; Choi, MS; Kwon, EY1
Chen, K; Gong, X; Gu, Y; Lang, H; Mi, M; Ran, L; Wang, X; Zhou, M; Zhou, Q; Zhu, J1
Lang, H; Liu, L; Mi, M; Zhou, M; Zhou, Y1
Fu, X; Hu, WZ; Li, CB; Li, XY; Li, Y; Shi, YS; Wu, J; Zhang, Y1
Dicks, L; Ellinger, S; Gronwald, D; Helfrich, HP; Kirch, N; Wernken, K; Zimmermann, BF1
Dicks, L; Ellinger, S; Helfrich, HP; Ludwig, N; Rynarzewski, J; Stoffel-Wagner, B; Zimmermann, BF1
Addington, AK; Bruno, RS; England, KM; Fausnacht, DW; Griffin, LE; Hughes, MD; Neilson, AP; O'Keefe, SF; Racine, KC; Stewart, AC; Tuzo, JL; Zhang, H1
Ge, C; Gu, T; Hu, L; Li, Q; Lou, D; Nie, X; Qin, Y; Tan, J; Wang, M; Xu, M1
Ho, CT; Lai, CS; Pan, MH; Tsai, ML1
Ali, M; Dorenkott, MR; Fundaro, G; Goodrich, KM; Griffin, LE; Hulver, MW; Neilson, AP; O'Keefe, SF; Stevens, JR; Thompson-Witrick, KA; Ye, L1
Cai, J; Zhao, L; Zhu, E1
Bocale, R; Desideri, G; Ferri, C; Grassi, D; Kwik-Uribe, C; Lechiara, MC; Marini, C; Mastroiacovo, D; Necozione, S; Pistacchio, L; Raffaele, A; Righetti, R1
Chen, M; Hu, Q; Huang, J; Liang, X; Mi, M; Shi, L; Zhang, Q; Zhang, T; Zhou, Y; Zhu, J1
Mi, M; Ran, L; Shi, L; Zeng, X; Zhang, Q; Zhang, T; Zhou, Y; Zhu, J1
Chen, S; Gao, Y; Liu, P; Mi, M; Qin, Y; Ran, L; Shu, F; Wan, J; Wang, X; Zhang, Q; Zhang, Y; Zhao, X; Zhu, J1
Goya, L; Martin, MÁ; Ramos, S1
Hu, K; Jiang, B; Le, L; Wan, W; Xiao, P; Xu, L; Zhai, W1
Lang, H; Liu, L; Mi, M; Si, M; Wan, J; Zhou, Y; Zhu, J1
Crandon, SK; Hall, G; Karne, RJ; Kolodziej, TL; Muniyappa, R; Quon, MJ1
Djoussé, L; Gaziano, JM; Khawaja, O1
Baer, DJ; Clevidence, BA; Henderson, T; Novotny, JA; Radecki, SV; Stote, KS1
Desideri, G; Ferri, C; Grassi, D; Lippi, C; Necozione, S1
Lan, TW; Liou, SS; Liu, IM; Tzeng, TF1

Reviews

3 review(s) available for 3-hydroxyflavone and Insulin Resistance

ArticleYear
Chemoprevention of nonalcoholic fatty liver disease by dietary natural compounds.
    Molecular nutrition & food research, 2014, Volume: 58, Issue:1

    Topics: Adipokines; Animals; Carotenoids; Curcumin; Fatty Acids, Omega-3; Fatty Liver; Flavonols; Humans; Insulin Resistance; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Polyphenols; Resveratrol; Stilbenes

2014
Antidiabetic actions of cocoa flavanols.
    Molecular nutrition & food research, 2016, Volume: 60, Issue:8

    Topics: Animals; Cacao; Diabetes Mellitus, Type 2; Diet; Flavonols; Humans; Hypoglycemic Agents; Insulin Resistance; Insulin-Secreting Cells; Polyphenols

2016
Chocolate and coronary heart disease: a systematic review.
    Current atherosclerosis reports, 2011, Volume: 13, Issue:6

    Topics: Cacao; Coronary Circulation; Coronary Disease; Endothelium, Vascular; Flavonols; Humans; Inflammation Mediators; Insulin Resistance; Lipids; Platelet Aggregation; Risk Factors

2011

Trials

7 trial(s) available for 3-hydroxyflavone and Insulin Resistance

ArticleYear
Regular Intake of a Usual Serving Size of Flavanol-Rich Cocoa Powder Does Not Affect Cardiometabolic Parameters in Stably Treated Patients with Type 2 Diabetes and Hypertension-A Double-Blinded, Randomized, Placebo-Controlled Trial.
    Nutrients, 2018, Oct-05, Volume: 10, Issue:10

    Topics: Adipose Tissue; Aged; Beverages; Blood Glucose; Blood Pressure; Body Weight; Cacao; Cardiovascular Diseases; Chocolate; Diabetes Mellitus, Type 2; Diet; Double-Blind Method; Female; Flavonols; Humans; Hypertension; Hypoglycemic Agents; Insulin Resistance; Lipids; Male; Middle Aged; Plant Extracts; Serving Size

2018
Impact of a Usual Serving Size of Flavanol-Rich Cocoa Powder Ingested with a Diabetic-Suitable Meal on Postprandial Cardiometabolic Parameters in Type 2 Diabetics-A Randomized, Placebo-Controlled, Double-Blind Crossover Study.
    Nutrients, 2019, Feb-16, Volume: 11, Issue:2

    Topics: Aged; Blood Glucose; Blood Pressure; Breakfast; Chocolate; Cholesterol; Cross-Over Studies; Diabetes Mellitus, Type 2; Diet, Diabetic; Double-Blind Method; Female; Flavonols; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Postprandial Period; Serving Size; Triglycerides

2019
Cocoa flavanol consumption improves cognitive function, blood pressure control, and metabolic profile in elderly subjects: the Cocoa, Cognition, and Aging (CoCoA) Study--a randomized controlled trial.
    The American journal of clinical nutrition, 2015, Volume: 101, Issue:3

    Topics: Aged; Aged, 80 and over; Aging; Antihypertensive Agents; Antioxidants; Beverages; Cacao; Cognition; Cognitive Dysfunction; Cohort Studies; Combined Modality Therapy; Dairy Products; Double-Blind Method; Female; Flavonols; Follow-Up Studies; Humans; Hypertension; Insulin Resistance; Lipid Peroxidation; Male; Nootropic Agents

2015
Dihydromyricetin improves glucose and lipid metabolism and exerts anti-inflammatory effects in nonalcoholic fatty liver disease: A randomized controlled trial.
    Pharmacological research, 2015, Volume: 99

    Topics: Adult; Ampelopsis; Biomarkers; Double-Blind Method; Female; Flavonols; Glucose; Humans; Insulin Resistance; Lipid Metabolism; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Plants, Medicinal

2015
Cocoa consumption for 2 wk enhances insulin-mediated vasodilatation without improving blood pressure or insulin resistance in essential hypertension.
    The American journal of clinical nutrition, 2008, Volume: 88, Issue:6

    Topics: Adult; Aged; Beverages; Brachial Artery; Cacao; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Female; Flavonols; Glucose Clamp Technique; Humans; Hypertension; Insulin; Insulin Resistance; Male; Middle Aged; Regional Blood Flow; Treatment Outcome; Young Adult

2008
Effect of cocoa and green tea on biomarkers of glucose regulation, oxidative stress, inflammation and hemostasis in obese adults at risk for insulin resistance.
    European journal of clinical nutrition, 2012, Volume: 66, Issue:10

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Beverages; Biomarkers; Body Mass Index; Cacao; Cross-Over Studies; District of Columbia; Double-Blind Method; Female; Fibrinogen; Flavonols; Hemostasis; Humans; Insulin Resistance; Male; Middle Aged; Obesity; Overweight; Oxidative Stress; Tea

2012
Short-term administration of dark chocolate is followed by a significant increase in insulin sensitivity and a decrease in blood pressure in healthy persons.
    The American journal of clinical nutrition, 2005, Volume: 81, Issue:3

    Topics: Adult; Analysis of Variance; Area Under Curve; Blood Glucose; Blood Pressure; Cacao; Candy; Cross-Over Studies; Dose-Response Relationship, Drug; Female; Flavonoids; Flavonols; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Insulin Resistance; Male; Phenols; Polyphenols

2005

Other Studies

16 other study(ies) available for 3-hydroxyflavone and Insulin Resistance

ArticleYear
Dihydromyricetin Ameliorates Inflammation-Induced Insulin Resistance via Phospholipase C-CaMKK-AMPK Signal Pathway.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: AMP-Activated Protein Kinases; Animals; Calcium-Calmodulin-Dependent Protein Kinase Kinase; Diabetes Mellitus, Type 2; Flavonols; Inflammation; Insulin Resistance; Male; Mice, Inbred C57BL; Signal Transduction

2021
Dihydromyricetin Improves High-Fat Diet-Induced Hyperglycemia through ILC3 Activation via a SIRT3-Dependent Mechanism.
    Molecular nutrition & food research, 2022, Volume: 66, Issue:16

    Topics: Animals; Diet, High-Fat; Flavonols; Hyperglycemia; Immunity, Innate; Insulin Resistance; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Sirtuin 3

2022
Oral flavonoid fisetin treatment protects against prolonged high-fat-diet-induced cardiac dysfunction by regulation of multicombined signaling.
    The Journal of nutritional biochemistry, 2020, Volume: 77

    Topics: Animals; Diet, High-Fat; Disease Models, Animal; Dyslipidemias; Echocardiography; Fibrosis; Flavonoids; Flavonols; Glucose Tolerance Test; Heart; Heart Diseases; Inflammation; Insulin; Insulin Resistance; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Signal Transduction

2020
Fisetin Alleviates Hepatic and Adipocyte Fibrosis and Insulin Resistance in Diet-Induced Obese Mice.
    Journal of medicinal food, 2020, Volume: 23, Issue:10

    Topics: Adipocytes; Adiposity; Animals; Diet, High-Fat; Flavonols; Insulin Resistance; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Mice, Obese

2020
Dihydromyricetin prevents obesity-induced slow-twitch-fiber reduction partially via FLCN/FNIP1/AMPK pathway.
    Biochimica et biophysica acta. Molecular basis of disease, 2017, Volume: 1863, Issue:6

    Topics: AMP-Activated Protein Kinases; Animals; Carrier Proteins; Dietary Fats; Flavonols; Gene Expression Regulation; Insulin Resistance; Male; Mice; Muscle Fibers, Slow-Twitch; Obesity; Proto-Oncogene Proteins; Signal Transduction; Tumor Suppressor Proteins

2017
Dihydromyricetin enhances glucose uptake by inhibition of MEK/ERK pathway and consequent down-regulation of phosphorylation of PPARγ in 3T3-L1 cells.
    Journal of cellular and molecular medicine, 2018, Volume: 22, Issue:2

    Topics: 3T3-L1 Cells; Adipocytes; Adipogenesis; Adiponectin; Anilides; Animals; Cell Survival; Dexamethasone; Down-Regulation; Fibroblast Growth Factors; Flavonoids; Flavonols; Glucose; Insulin Resistance; MAP Kinase Signaling System; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Phosphoserine; PPAR gamma

2018
Fisetin Attenuates Metabolic Dysfunction in Mice Challenged with a High-Fructose Diet.
    Journal of agricultural and food chemistry, 2018, Aug-08, Volume: 66, Issue:31

    Topics: Animals; Antioxidants; Diet; Flavonoids; Flavonols; Fructose; Inflammation; Insulin Resistance; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress

2018
Flavanol supplementation protects against obesity-associated increases in systemic interleukin-6 levels without inhibiting body mass gain in mice fed a high-fat diet.
    Nutrition research (New York, N.Y.), 2019, Volume: 66

    Topics: Adipose Tissue; Animals; Body Composition; Diet, High-Fat; Dietary Supplements; Eating; Flavonols; Glucose Intolerance; Grape Seed Extract; Inflammation; Insulin Resistance; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Obesity; Pinus; Plant Bark; Weight Gain

2019
Fisetin supplementation prevents high fat diet-induced diabetic nephropathy by repressing insulin resistance and RIP3-regulated inflammation.
    Food & function, 2019, May-22, Volume: 10, Issue:5

    Topics: Animals; Diabetic Nephropathies; Diet, High-Fat; Flavonoids; Flavonols; Forkhead Box Protein O1; Hepatitis A Virus Cellular Receptor 1; Humans; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; NLR Family, Pyrin Domain-Containing 3 Protein; Receptor-Interacting Protein Serine-Threonine Kinases

2019
Oligomeric cocoa procyanidins possess enhanced bioactivity compared to monomeric and polymeric cocoa procyanidins for preventing the development of obesity, insulin resistance, and impaired glucose tolerance during high-fat feeding.
    Journal of agricultural and food chemistry, 2014, Mar-12, Volume: 62, Issue:10

    Topics: Animals; Biflavonoids; Body Composition; Cacao; Catechin; Chromatography, High Pressure Liquid; Diet, High-Fat; Eating; Flavonols; Glucose Intolerance; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Obesity; Proanthocyanidins; Structure-Activity Relationship; Tandem Mass Spectrometry; Weight Gain

2014
A new flavonol triglycoside derived from Anoectochilus elwesii on stimulating glucose uptake in insulin-induced human HepG2 cells.
    Natural product research, 2015, Volume: 29, Issue:15

    Topics: Flavonols; Glucose; Glycosides; Hep G2 Cells; Humans; Insulin Resistance; Molecular Structure; Orchidaceae

2015
Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway.
    Molecular and cellular endocrinology, 2015, Jul-05, Volume: 409

    Topics: Adenine; AMP-Activated Protein Kinases; Animals; Autophagy; Cells, Cultured; Diabetes Mellitus, Type 2; Diet, High-Fat; Flavonols; Gene Expression Regulation; Insulin Resistance; Macrolides; Male; Muscle, Skeletal; Phosphorylation; Rats; Rats, Sprague-Dawley; Signal Transduction

2015
Dihydromyricetin improves skeletal muscle insulin sensitivity by inducing autophagy via the AMPK-PGC-1α-Sirt3 signaling pathway.
    Endocrine, 2015, Volume: 50, Issue:2

    Topics: AMP-Activated Protein Kinases; Animals; Autophagy; Flavonols; Insulin Resistance; Male; Mice; Mice, 129 Strain; Muscle, Skeletal; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Signal Transduction; Sirtuin 3; Transcription Factors

2015
Metabolomics reveals the protective of Dihydromyricetin on glucose homeostasis by enhancing insulin sensitivity.
    Scientific reports, 2016, 10-31, Volume: 6

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Animals; Citric Acid Cycle; Diet, High-Fat; Flavonols; Glucose; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Hyperglycemia; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Metabolic Networks and Pathways; Protective Agents; Protein Serine-Threonine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Up-Regulation

2016
Dihydromyricetin delays the onset of hyperglycemia and ameliorates insulin resistance without excessive weight gain in Zucker diabetic fatty rats.
    Molecular and cellular endocrinology, 2017, 01-05, Volume: 439

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Progression; Flavonols; Hyperglycemia; Insulin Resistance; Male; Obesity; Rats; Rats, Zucker; Time Factors; Weight Gain

2017
Myricetin, a naturally occurring flavonol, ameliorates insulin resistance induced by a high-fructose diet in rats.
    Life sciences, 2007, Nov-10, Volume: 81, Issue:21-22

    Topics: Animals; Blood Glucose; Blotting, Western; Cholesterol; Diet; Electrophoresis, Polyacrylamide Gel; Flavonoids; Flavonols; Fructose; Glucose Transporter Type 4; Glycogen; Hepatocytes; Hypoglycemic Agents; Immunoprecipitation; Insulin; Insulin Resistance; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin; Rosiglitazone; Thiazolidinediones; Triglycerides

2007