Page last updated: 2024-08-21

3-hydroxyflavone and Hepatocellular Carcinoma

3-hydroxyflavone has been researched along with Hepatocellular Carcinoma in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (20.83)29.6817
2010's14 (58.33)24.3611
2020's5 (20.83)2.80

Authors

AuthorsStudies
Liu, Y; Mei, F; Zheng, S1
Kozawa, O; Matsushima-Nishiwaki, R; Yamada, N1
Panneerselvam, L; Perumal, E; Raghunath, A; Sundarraj, K1
Dai, W; Jiang, L; Li, M; Li, Z; Yang, Y; Ye, WC1
Bi, Y; Chen, J; Fu, J; Liu, B; Wang, X; Xia, T; Zhu, R1
Liu, GL; Liu, XF; Long, HJ; Miao, XY; Yao, HL1
Duan, J; He, YF; He, YH; Li, MY; Liang, YR; Lu, CJ; Xiang, LJ; Yuan, WZ; Zhang, J1
Maurya, BK; Trigun, SK2
Chen, Q; Fan, X; Li, J; Peng, Y; Pu, W; Shen, X; Wang, C; Wu, X; Yang, SY; Yu, Y; Zheng, Y; Zhou, Q1
Hu, M; Huang, H; Li, M; Li, P; Zhao, R1
Cao, Y; Chen, N; Chen, X; Li, M; Liu, B; Liu, J; Lu, C; Xia, J; Zhang, C; Zhang, Q; Zhu, R1
Li, MY; Li, R; Liu, B; Liu, J; Liu, ZK; Miao, HL; Qiu, ZD; Shu, Y; Wang, DJ; Zeng, GF; Zhang, QY; Zhu, RZ1
Bao, S; Chen, N; Chen, X; Chen, Y; Li, M; Liu, B; Liu, J; Xu, F; Zhang, Q; Zhou, W; Zhu, R1
Jiang, L; Li, M; Liang, J; Liu, B; Liu, J; Lu, C; Ma, S; Ren, H; Zhang, Q; Zhu, R1
Barros, L; Calhelha, RC; Carvalho, AM; Dias, MI; Ferreira, IC; Graça, VC; Santos, PF; Santos-Buelga, C1
Chang, JJ; Li, LJ; Li, X; Lu, R; Sun, X; Wang, QL; Xie, WD; Zhao, XX1
Aristizabal, F; Barrios, J; Cordero, CP; Heredia, FJ; Morales, AL; Osorio, C1
Choi, KC; Chung, WT; Jang, YS; Kwon, JK; Lee, JC; Lee, SY; Park, SM; Yu, JY1
Casaschi, A; Maiyoh, GK; Rubio, BK; Theriault, AG1
Lu, YH; Tao, XY; Teng, BS; Wang, ZT; Wei, DZ1
Konta, L; Révész, K; Tüttô, A1
Fung, KP; Gao, JL; Lee, SM; Sa, F; Wang, YT; Zheng, Y1
Chen, YC; Ko, CH; Lee, WR; Lin, HY; Shen, SC; Shih, CM; Yang, LL1

Reviews

2 review(s) available for 3-hydroxyflavone and Hepatocellular Carcinoma

ArticleYear
Molecular mechanisms and therapeutic implications of dihydromyricetin in liver disease.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Carcinoma, Hepatocellular; Flavonols; Humans; Liver Diseases; Liver Diseases, Alcoholic; Liver Failure, Acute; Liver Neoplasms; Liver Regeneration; Non-alcoholic Fatty Liver Disease; Protective Agents

2021
[Effect of green tea flavonols on the function of the endoplasmic reticulum].
    Orvosi hetilap, 2007, Oct-07, Volume: 148, Issue:40

    Topics: alpha-Glucosidases; Animals; Antineoplastic Agents; Apoptosis; Blood Glucose; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Endoplasmic Reticulum; Flavonols; Glucuronides; Glycoside Hydrolase Inhibitors; Humans; Hypoglycemic Agents; Liver; Liver Neoplasms; Microsomes; Tea

2007

Other Studies

22 other study(ies) available for 3-hydroxyflavone and Hepatocellular Carcinoma

ArticleYear
Rhamnazin Inhibits Hepatocellular Carcinoma Cell Aggressiveness in Vitro via Glutathione Peroxidase 4-Dependent Ferroptosis.
    The Tohoku journal of experimental medicine, 2022, Sep-13, Volume: 258, Issue:2

    Topics: Carcinoma, Hepatocellular; Ferroptosis; Flavonols; Glutathione Peroxidase; Humans; Liver Neoplasms; Phospholipid Hydroperoxide Glutathione Peroxidase

2022
Quercetin suppresses the migration of hepatocellular carcinoma cells stimulated by hepatocyte growth factor or transforming growth factor-α: Attenuation of AKT signaling pathway.
    Archives of biochemistry and biophysics, 2020, 03-30, Volume: 682

    Topics: Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Flavonols; Gene Expression Regulation, Neoplastic; Hepatocyte Growth Factor; Humans; Liver Neoplasms; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Quercetin; Signal Transduction; Transforming Growth Factor alpha

2020
Fisetin Inhibits Autophagy in HepG2 Cells via PI3K/Akt/mTOR and AMPK Pathway.
    Nutrition and cancer, 2021, Volume: 73, Issue:11-12

    Topics: AMP-Activated Protein Kinases; Apoptosis; Autophagy; Carcinoma, Hepatocellular; Flavonols; Hep G2 Cells; Humans; Liver Neoplasms; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; TOR Serine-Threonine Kinases

2021
Anticancer effects of dihydromyricetin on the proliferation, migration, apoptosis and in vivo tumorigenicity of human hepatocellular carcinoma Hep3B cells.
    BMC complementary medicine and therapies, 2021, Jul-06, Volume: 21, Issue:1

    Topics: Animals; Apoptosis; Carcinogenesis; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Flavonols; Humans; In Vitro Techniques; Liver Neoplasms; Mice; Mice, Nude; Random Allocation

2021
Fisetin inhibits liver cancer growth in a mouse model: Relation to dopamine receptor.
    Oncology reports, 2017, Volume: 38, Issue:1

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Flavonoids; Flavonols; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Receptors, Dopamine; Signal Transduction; Transforming Growth Factor beta1; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2017
Dihydromyricetin-mediated inhibition of the Notch1 pathway induces apoptosis in QGY7701 and HepG2 hepatoma cells.
    World journal of gastroenterology, 2017, Sep-14, Volume: 23, Issue:34

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Cell Proliferation; Disease Progression; Down-Regulation; Flavonols; Flow Cytometry; Hep G2 Cells; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-bcl-2; Receptor, Notch1; RNA Interference; RNA, Small Interfering; Signal Transduction; Up-Regulation

2017
Fisetin Attenuates AKT Associated Growth Promoting Events in AflatoxinB1 Induced Hepatocellular Carcinoma.
    Anti-cancer agents in medicinal chemistry, 2018, Volume: 18, Issue:13

    Topics: Aflatoxin B1; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Proliferation; Drug Screening Assays, Antitumor; Flavonoids; Flavonols; Liver Neoplasms; Male; Proto-Oncogene Proteins c-akt; Rats; Structure-Activity Relationship

2018
Discovery of a Prenylated Flavonol Derivative as a Pin1 Inhibitor to Suppress Hepatocellular Carcinoma by Modulating MicroRNA Biogenesis.
    Chemistry, an Asian journal, 2019, Jan-04, Volume: 14, Issue:1

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Computer-Aided Design; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Flavonols; Humans; Liver Neoplasms; MicroRNAs; Molecular Structure; NIMA-Interacting Peptidylprolyl Isomerase; Real-Time Polymerase Chain Reaction; Structure-Activity Relationship; Time Factors

2019
Dihydromyricetin suppresses the proliferation of hepatocellular carcinoma cells by inducing G2/M arrest through the Chk1/Chk2/Cdc25C pathway.
    Oncology reports, 2013, Volume: 30, Issue:5

    Topics: Carcinoma, Hepatocellular; cdc25 Phosphatases; Cell Proliferation; Checkpoint Kinase 1; Checkpoint Kinase 2; Flavonols; G2 Phase Cell Cycle Checkpoints; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Protein Kinases; Signal Transduction

2013
Dihydromyricetin promotes hepatocellular carcinoma regression via a p53 activation-dependent mechanism.
    Scientific reports, 2014, Apr-10, Volume: 4

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cisplatin; Enzyme Activation; Flavonols; Hep G2 Cells; Humans; Liver; Liver Neoplasms; Male; Medicine, Chinese Traditional; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphorylation; RNA Interference; RNA, Small Interfering; Signal Transduction; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2014
Dihydromyricetin inhibits migration and invasion of hepatoma cells through regulation of MMP-9 expression.
    World journal of gastroenterology, 2014, Aug-07, Volume: 20, Issue:29

    Topics: Antineoplastic Agents, Phytogenic; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Cell Movement; Cell Survival; Dose-Response Relationship, Drug; Down-Regulation; Flavonols; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Phosphorylation; Protein Kinase C-delta; Signal Transduction; Time Factors

2014
Dihydromyricetin induces mouse hepatoma Hepal-6 cell apoptosis via the transforming growth factor-β pathway.
    Molecular medicine reports, 2015, Volume: 11, Issue:3

    Topics: Adenosine Triphosphate; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Flavonols; Liver Neoplasms; Mice; Models, Biological; NADPH Oxidase 4; NADPH Oxidases; Reactive Oxygen Species; Signal Transduction; Transforming Growth Factor beta

2015
Dihydromyricetin Enhances the Chemo-Sensitivity of Nedaplatin via Regulation of the p53/Bcl-2 Pathway in Hepatocellular Carcinoma Cells.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Synergism; Flavonols; Humans; Liver Neoplasms; Organoplatinum Compounds; Proto-Oncogene Proteins c-bcl-2; Tumor Suppressor Protein p53

2015
Fisetin Modulates Antioxidant Enzymes and Inflammatory Factors to Inhibit Aflatoxin-B1 Induced Hepatocellular Carcinoma in Rats.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Aflatoxin B1; Animals; Antioxidants; Carcinoma, Hepatocellular; Flavonoids; Flavonols; Interleukin-1alpha; Liver Neoplasms, Experimental; Male; Neoplasm Proteins; Oxidative Stress; Oxidoreductases; Rats; Tumor Necrosis Factor-alpha

2016
Chemical characterization and bioactive properties of Geranium molle L.: from the plant to the most active extract and its phytochemicals.
    Food & function, 2016, May-18, Volume: 7, Issue:5

    Topics: Animals; Antioxidants; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Fatty Acids, Essential; Flavones; Flavonoids; Flavonols; Free Radical Scavengers; Geranium; Glycosides; Humans; Hydrolyzable Tannins; Lipid Peroxidation; Nutritive Value; Phytochemicals; Plant Extracts; Portugal; Primary Cell Culture; Swine; Tocopherols

2016
5,6-Dihydroxy-3,7,4'-trimethoxyflavonol induces G2/M cell cycle arrest and apoptosis in human hepatocellular carcinoma cells.
    Journal of Asian natural products research, 2016, Volume: 18, Issue:11

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Caspase 9; Cyclin B1; Cytochromes c; Drug Design; Flavonoids; Flavonols; G2 Phase Cell Cycle Checkpoints; Hep G2 Cells; Humans; Indoles; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Molecular Structure; Proto-Oncogene Proteins c-bcl-2; Structure-Activity Relationship

2016
Chemical analysis and screening as anticancer agent of anthocyanin-rich extract from Uva Caimarona ( Pourouma cecropiifolia Mart.) fruit.
    Journal of agricultural and food chemistry, 2010, Feb-24, Volume: 58, Issue:4

    Topics: Anthocyanins; Antineoplastic Agents; Breast Neoplasms; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Chromatography, High Pressure Liquid; Ecosystem; Ericaceae; Female; Flavonols; Fruit; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mass Spectrometry; Plant Extracts; Tropical Climate

2010
Inhibitory effects of quercetin on aflatoxin B1-induced hepatic damage in mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2010, Volume: 48, Issue:10

    Topics: Aflatoxin B1; Animals; Body Weight; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Flavonols; Glutathione; Humans; Liver; Male; Malondialdehyde; Mice; Mice, Inbred ICR; Organ Size; Quercetin; Reactive Oxygen Species

2010
Inhibitory activity of diacylglycerol acyltransferase (DGAT) and microsomal triglyceride transfer protein (MTP) by the flavonoid, taxifolin, in HepG2 cells: potential role in the regulation of apolipoprotein B secretion.
    Atherosclerosis, 2004, Volume: 176, Issue:2

    Topics: Acyltransferases; Anti-Inflammatory Agents, Non-Steroidal; Apolipoproteins B; Carcinoma, Hepatocellular; Carrier Proteins; Diacylglycerol O-Acyltransferase; Enzyme-Linked Immunosorbent Assay; Flavonols; Humans; Liver Neoplasms; Quercetin; Tumor Cells, Cultured

2004
In vitro anti-tumor activity of isorhamnetin isolated from Hippophae rhamnoides L. against BEL-7402 cells.
    Pharmacological research, 2006, Volume: 54, Issue:3

    Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Chromatography, High Pressure Liquid; Flavonols; G1 Phase; Hippophae; Humans; Liver Neoplasms; Quercetin

2006
Anti-proliferative and pro-apoptotic effect of Smilax glabra Roxb. extract on hepatoma cell lines.
    Chemico-biological interactions, 2008, Jan-10, Volume: 171, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytochromes c; Drugs, Chinese Herbal; Flavonols; Gene Expression; Humans; Inhibitory Concentration 50; Liver Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinases; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Smilax; Spirostans

2008
Wogonin and fisetin induction of apoptosis through activation of caspase 3 cascade and alternative expression of p21 protein in hepatocellular carcinoma cells SK-HEP-1.
    Archives of toxicology, 2002, Volume: 76, Issue:5-6

    Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Caspase 1; Caspase 3; Caspases; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Enzyme Activation; Flavanones; Flavonoids; Flavonols; Flow Cytometry; Humans; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002