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3-hydroxybutyric acid and Status Epilepticus

3-hydroxybutyric acid has been researched along with Status Epilepticus in 3 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Status Epilepticus: A prolonged seizure or seizures repeated frequently enough to prevent recovery between episodes occurring over a period of 20-30 minutes. The most common subtype is generalized tonic-clonic status epilepticus, a potentially fatal condition associated with neuronal injury and respiratory and metabolic dysfunction. Nonconvulsive forms include petit mal status and complex partial status, which may manifest as behavioral disturbances. Simple partial status epilepticus consists of persistent motor, sensory, or autonomic seizures that do not impair cognition (see also EPILEPSIA PARTIALIS CONTINUA). Subclinical status epilepticus generally refers to seizures occurring in an unresponsive or comatose individual in the absence of overt signs of seizure activity. (From N Engl J Med 1998 Apr 2;338(14):970-6; Neurologia 1997 Dec;12 Suppl 6:25-30)

Research Excerpts

ExcerptRelevanceReference
" These issues are being addressed by designing and synthesizing orally bioavailable multimers of betaOHB with improved pharmacokinetics."2.43KTX 0101: a potential metabolic approach to cytoprotection in major surgery and neurological disorders. ( Heal, DJ; Martin, KF; Smith, SL, 2005)
"One patient with severe dilated cardiomyopathy and prolonged QTc normalized when the diet was discontinued."1.31Cardiac complications in pediatric patients on the ketogenic diet. ( Best, TH; Epstein, MR; Franz, DN; Gilbert, DL; Nelson, DP, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cobo, NH1
Sankar, R1
Murata, KK1
Sewak, SL1
Kezele, MA1
Matsumoto, JH1
Smith, SL1
Heal, DJ1
Martin, KF1
Best, TH1
Franz, DN1
Gilbert, DL1
Nelson, DP1
Epstein, MR1

Reviews

1 review available for 3-hydroxybutyric acid and Status Epilepticus

ArticleYear
KTX 0101: a potential metabolic approach to cytoprotection in major surgery and neurological disorders.
    CNS drug reviews, 2005,Summer, Volume: 11, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Brain Infarction; Cell Death; Disease Models

2005

Other Studies

2 other studies available for 3-hydroxybutyric acid and Status Epilepticus

ArticleYear
The ketogenic diet as broad-spectrum treatment for super-refractory pediatric status epilepticus: challenges in implementation in the pediatric and neonatal intensive care units.
    Journal of child neurology, 2015, Volume: 30, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adolescent; Blood Glucose; Child; Diet, Ketogenic; Electroencephalography; Fe

2015
Cardiac complications in pediatric patients on the ketogenic diet.
    Neurology, 2000, Jun-27, Volume: 54, Issue:12

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Arrhythmias, Cardiac; Cardiomyopathy, Dilated; Cardiovascu

2000