3-hydroxybutyric acid has been researched along with Spasms, Infantile in 3 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Spasms, Infantile: An epileptic syndrome characterized by the triad of infantile spasms, hypsarrhythmia, and arrest of psychomotor development at seizure onset. The majority present between 3-12 months of age, with spasms consisting of combinations of brief flexor or extensor movements of the head, trunk, and limbs. The condition is divided into two forms: cryptogenic (idiopathic) and symptomatic (secondary to a known disease process such as intrauterine infections; nervous system abnormalities; BRAIN DISEASES, METABOLIC, INBORN; prematurity; perinatal asphyxia; TUBEROUS SCLEROSIS; etc.). (From Menkes, Textbook of Child Neurology, 5th ed, pp744-8)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ketogenic diet (KD) is a treatment of infantile spasms (IS)." | 1.37 | The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms. ( Chu-Shore, CJ; Numis, AL; Pfeifer, HH; Thiele, EA; Yellen, MB, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Janicot, R | 1 |
| Shao, LR | 1 |
| Stafstrom, CE | 1 |
| Yum, MS | 1 |
| Lee, M | 1 |
| Woo, DC | 1 |
| Kim, DW | 1 |
| Ko, TS | 1 |
| Velíšek, L | 1 |
| Numis, AL | 1 |
| Yellen, MB | 1 |
| Chu-Shore, CJ | 1 |
| Pfeifer, HH | 1 |
| Thiele, EA | 1 |
3 other studies available for 3-hydroxybutyric acid and Spasms, Infantile
| Article | Year |
|---|---|
2-deoxyglucose and β-hydroxybutyrate fail to attenuate seizures in the betamethasone-NMDA model of infantile spasms.
Topics: 3-Hydroxybutyric Acid; Adrenocorticotropic Hormone; Animals; Animals, Newborn; Betamethasone; Deoxyg | 2022 |
β-Hydroxybutyrate attenuates NMDA-induced spasms in rats with evidence of neuronal stabilization on MR spectroscopy.
Topics: 3-Hydroxybutyric Acid; Animals; Anticonvulsants; Brain; Disease Models, Animal; Humans; Infant, Newb | 2015 |
The relationship of ketosis and growth to the efficacy of the ketogenic diet in infantile spasms.
Topics: 3-Hydroxybutyric Acid; Anthropometry; Blood Glucose; Body Height; Body Weight; Cohort Studies; Diet, | 2011 |