3-hydroxybutyric acid has been researched along with Pregnancy in Diabetes in 40 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Our results suggest that genetic susceptibility plays an important role in inducing underdevelopment and NTD in cultured CDs embryos in sub-teratogenic medium and in protecting the CDr embryos under the same conditions." | 1.32 | Reduced SOD activity and increased neural tube defects in embryos of the sensitive but not of the resistant Cohen diabetic rats cultured under diabetic conditions. ( Ornoy, A; Weksler-Zangen, S; Yaffe, P, 2003) |
| "Furthermore, the occurrence of fasting hypoglycemia necessitates careful monitoring of postnatal blood glucose values." | 1.27 | Intrauterine growth and postnatal fasting metabolism in infants of obese mothers. ( Dunnington, R; Gross, T; Kliegman, R; Morton, S, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (50.00) | 18.7374 |
| 1990's | 15 (37.50) | 18.2507 |
| 2000's | 2 (5.00) | 29.6817 |
| 2010's | 3 (7.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harris, DL | 1 |
| Weston, PJ | 1 |
| Harding, JE | 1 |
| Stenerson, MB | 1 |
| Collura, CA | 1 |
| Rose, CH | 1 |
| Lteif, AN | 1 |
| Carey, WA | 1 |
| Cetin, H | 1 |
| Yalaz, M | 1 |
| Akisu, M | 1 |
| Kultursay, N | 1 |
| Weksler-Zangen, S | 1 |
| Yaffe, P | 2 |
| Ornoy, A | 3 |
| Stangenberg, M | 1 |
| Persson, B | 4 |
| Fredholm, BB | 1 |
| Lundblad, BS | 1 |
| Stånge, L | 1 |
| Kliegman, R | 1 |
| Gross, T | 1 |
| Morton, S | 1 |
| Dunnington, R | 1 |
| Hertz, RH | 1 |
| King, KC | 1 |
| Kalhan, SC | 2 |
| Miodovnik, M | 2 |
| Lavin, JP | 1 |
| Harrington, DJ | 2 |
| Leung, LS | 1 |
| Seeds, AE | 1 |
| Clark, KE | 2 |
| Horton, WE | 2 |
| Sadler, TW | 4 |
| Tserng, KY | 1 |
| Gilfillan, C | 1 |
| Dierker, LJ | 1 |
| Schmidt-Sommerfeld, E | 1 |
| Penn, D | 1 |
| Wolf, H | 1 |
| Nisell, H | 1 |
| Hanson, U | 2 |
| Lunell, NO | 2 |
| Nylund, L | 1 |
| Sarby, B | 1 |
| Thronström, S | 1 |
| Moley, KH | 1 |
| Vaughn, WK | 1 |
| Diamond, MP | 2 |
| Rossi, G | 1 |
| Lapaczewski, P | 1 |
| Jacob, RJ | 1 |
| Shulman, GI | 1 |
| Sherwin, RS | 1 |
| Eriksson, UJ | 3 |
| Borg, LA | 1 |
| McLean, MP | 1 |
| Warden, KJ | 1 |
| Sandhoff, TW | 1 |
| Irby, RB | 1 |
| Hales, DB | 1 |
| Viana, M | 1 |
| Herrera, E | 3 |
| Bonet, B | 1 |
| Edwall, L | 1 |
| Nord, E | 1 |
| Westgren, M | 1 |
| Jovanovic, L | 1 |
| Metzger, BE | 4 |
| Knopp, RH | 1 |
| conley, MR | 1 |
| Park, E | 1 |
| Lee, YJ | 1 |
| Simpson, JL | 1 |
| Holmes, L | 1 |
| Aarons, JH | 1 |
| Mills, JL | 1 |
| Zaken, V | 1 |
| Kohen, R | 1 |
| Lapidot, A | 1 |
| Haber, S | 1 |
| Chan, SP | 1 |
| Gelding, SV | 1 |
| McManus, RJ | 1 |
| Nicholls, JS | 1 |
| Anyaoku, V | 1 |
| Niththyananthan, R | 1 |
| Johnston, DG | 1 |
| Dornhorst, A | 1 |
| Montelongo, A | 1 |
| Lasunción, MA | 2 |
| Pallardo, LF | 1 |
| Styrud, J | 2 |
| Rizzo, T | 2 |
| Burns, WJ | 2 |
| Burns, K | 1 |
| Freinkel, N | 2 |
| Hatcher, R | 1 |
| Barglow, P | 1 |
| Moore, DC | 1 |
| Stanisstreet, M | 1 |
| Clarke, CA | 1 |
| Hunter, ES | 2 |
| Wynn, RE | 1 |
| Phillips, LS | 1 |
| Pschera, H | 1 |
| Gillmer, MD | 2 |
| Maresh, M | 2 |
| Beard, RW | 2 |
| Elkeles, RS | 2 |
| Alderson, C | 1 |
| Bloxham, B | 1 |
| Zusman, I | 1 |
| Karlsson, MG | 1 |
| Palacin, M | 1 |
| Martin, A | 1 |
| Alderson, CS | 1 |
| Bloxham, BA | 1 |
| Kalkhoff, RK | 1 |
| Bourbon, JR | 1 |
| Pignol, B | 1 |
| Marin, L | 1 |
| Rieutort, M | 1 |
| Tordet, C | 1 |
| Skillman, CA | 1 |
| Hertzberg, V | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Maternal-fetal Gradient of Free and Esterified Phytosterols in Term Human Pregnancy at Delivery[NCT03705767] | 68 participants (Actual) | Observational | 2016-10-26 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for 3-hydroxybutyric acid and Pregnancy in Diabetes
| Article | Year |
|---|---|
Mouse embryos in culture: models for understanding diabetes-induced embryopathies and gene function.
Topics: 3-Hydroxybutyric Acid; Animals; Culture Techniques; Disease Models, Animal; Embryonic and Fetal Deve | 1997 |
Mechanisms of congenital malformations in diabetic pregnancy.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Congenital Abnormalities; Diabetes Mellitus, Experime | 1987 |
Accelerated starvation in pregnancy: implications for dietary treatment of obesity and gestational diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus; Fasting; Fatty Acids, Nonesterified; Female | 1987 |
Therapeutic results of insulin therapy in gestational diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Birth Weight; Blood Glucose; Body Weight; Delivery, Obstetric; F | 1985 |
2 trials available for 3-hydroxybutyric acid and Pregnancy in Diabetes
| Article | Year |
|---|---|
Lactate, rather than ketones, may provide alternative cerebral fuel in hypoglycaemic newborns.
Topics: 3-Hydroxybutyric Acid; Biomarkers; Birth Weight; Blood Glucose; Breast Feeding; Double-Blind Method; | 2015 |
Low energy diets in the treatment of gestational diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Circadian Rhythm; Diet, Reducing; Energy Intake; Female | 1986 |
34 other studies available for 3-hydroxybutyric acid and Pregnancy in Diabetes
| Article | Year |
|---|---|
Bilateral basal ganglia infarctions in a neonate born during maternal diabetic ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Adult; Basal Ganglia Cerebrovascular Disease; Brain Infarction; Dehydration; | 2011 |
Polycythaemia in infants of diabetic mothers: β-hydroxybutyrate stimulates erythropoietic activity.
Topics: 3-Hydroxybutyric Acid; Adult; Case-Control Studies; Erythropoiesis; Female; Fetal Hemoglobin; Glycat | 2011 |
Reduced SOD activity and increased neural tube defects in embryos of the sensitive but not of the resistant Cohen diabetic rats cultured under diabetic conditions.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Catalase; Diabetes Mellitus, Type 2; Disease Models, | 2003 |
Insulin-induced hypoglycaemia in diabetic women during late pregnancy and one year post partum.
Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Blood Glucose; C-Peptide; Cyclic AMP; Fatty Acids, Nonest | 1981 |
Intrauterine growth and postnatal fasting metabolism in infants of obese mothers.
Topics: 3-Hydroxybutyric Acid; Birth Weight; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified | 1984 |
Management of third-trimester diabetic pregnancies with the use of continuous subcutaneous insulin infusion therapy: a pilot study.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Diabetes Mellitus, Type 1; Female; Humans; Hydroxybutyrates; I | 1984 |
Effect of maternal ketoacidemia on the pregnant ewe and the fetus.
Topics: 3-Hydroxybutyric Acid; Amniotic Fluid; Animals; Antipyrine; Diabetic Ketoacidosis; Female; Fetus; He | 1982 |
Effects of maternal diabetes on early embryogenesis. Alterations in morphogenesis produced by the ketone body, B-hydroxybutyrate.
Topics: 3-Hydroxybutyric Acid; Animals; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Gestati | 1983 |
Metabolism of urea and glucose in normal and diabetic pregnancy.
Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Blood Glucose; Blood Urea Nitrogen; Fasting; Female; Gluc | 1982 |
The influence of maternal fat metabolism on fetal carnitine levels.
Topics: 3-Hydroxybutyric Acid; Amniotic Fluid; Carnitine; Fatty Acids; Female; Fetus; Humans; Hydroxybutyrat | 1981 |
Hormonal, metabolic, and circulatory responses to insulin-induced hypoglycemia in pregnant and nonpregnant women with insulin-dependent diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Circulation; Blood Glucose; Blood Pressure; Catecholamines; Diab | 1994 |
Manifestations of diabetes mellitus on mouse preimplantation development: effect of elevated concentration of metabolic intermediates.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Butyrates; Cleavage Stage, Ovum; Culture | 1994 |
Inhibitory effect of pregnancy on counterregulatory hormone responses to hypoglycemia in awake rat.
Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Blood Glucose; Epinephrine; Fasting; Female; G | 1993 |
Diabetes and embryonic malformations. Role of substrate-induced free-oxygen radical production for dysmorphogenesis in cultured rat embryos.
Topics: 3-Hydroxybutyric Acid; Animals; Congenital Abnormalities; Culture Techniques; Embryo, Mammalian; Fem | 1993 |
Altered ovarian sterol carrier protein expression in the pregnant streptozotocin-treated diabetic rat.
Topics: 3-Hydroxybutyric Acid; 3-Hydroxysteroid Dehydrogenases; Acetyl-CoA C-Acetyltransferase; Animals; Blo | 1996 |
Teratogenic effects of diabetes mellitus in the rat. Prevention by vitamin E.
Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Cholesterol; Congenital Abnormalities; Diabete | 1996 |
Insulin sensitivity and insulin response in women with gestational diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Fatty Acids, Nonesterified; Female; Glucose Tolerance Test; Humans; Hy | 1997 |
The Diabetes in Early Pregnancy Study: beta-hydroxybutyrate levels in type 1 diabetic pregnancy compared with normal pregnancy. NICHD-Diabetes in Early Pregnancy Study Group (DIEP). National Institute of Child Health and Development.
Topics: 3-Hydroxybutyric Acid; Abortion, Spontaneous; Adult; Cohort Studies; Diabetes Mellitus, Type 1; Fast | 1998 |
Role of reactive oxygen species (ROS) in the diabetes-induced anomalies in rat embryos in vitro: reduction in antioxidant enzymes and low-molecular-weight antioxidants (LMWA) may be the causative factor for increased anomalies.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Antioxidants; Ascorbic Acid; Catalase; Congenital Abn | 1999 |
Effect of endogenous beta-hydroxybutyrate on brain glucose metabolism in fetuses of diabetic rabbits, studied by (13)C magnetic resonance spectroscopy.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Blood Glucose; Brain; Carbon Isotopes; Diabetes Mellitu | 2002 |
Abnormalities of intermediary metabolism following a gestational diabetic pregnancy.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Diabetes Mellitus; Female; Glucose Tolerance Test; Glyc | 1992 |
Longitudinal study of plasma lipoproteins and hormones during pregnancy in normal and diabetic women.
Topics: 3-Hydroxybutyric Acid; Adult; Analysis of Variance; Apolipoproteins; Body Mass Index; Cholesterol; D | 1992 |
Development of rat embryos in culture media containing different concentrations of normal and diabetic rat serum.
Topics: 3-Hydroxybutyric Acid; Animals; Biological Transport, Active; Congenital Abnormalities; Culture Medi | 1992 |
Correlations between antepartum maternal metabolism and intelligence of offspring.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Child Development; Child, Preschool; Fatty Acids, Nonesterifie | 1991 |
Correlations between antepartum maternal metabolism and newborn behavior.
Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Behavior; Blood Glucose; Chi-Square Distribution; Femal | 1990 |
Morphological and physiological effects of beta-hydroxybutyrate on rat embryos grown in vitro at different stages.
Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Diabetes Mellitus, Experimental; Embryo, Mamma | 1989 |
Evidence for multifactorial origin of diabetes-induced embryopathies.
Topics: 3-Hydroxybutyric Acid; Animals; Congenital Abnormalities; Diabetes Mellitus, Experimental; Female; F | 1989 |
Interrelation between glucose, insulin, C-peptide and 3-hydroxybutyrate in plasma and amniotic fluid in last trimester diabetic women without residual betacell function.
Topics: 3-Hydroxybutyric Acid; Amniotic Fluid; Blood Glucose; C-Peptide; Female; Humans; Hydroxybutyrates; I | 1988 |
Effects of metabolic factors in the diabetic state on the in vitro development of preimplantation mouse embryos.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blastocyst; Culture Techniques; Diabetes Mellitus, Ex | 1987 |
Mammalian embryos in culture: a new approach to investigating normal and abnormal developmental mechanisms.
Topics: 3-Hydroxybutyric Acid; Animals; Congenital Abnormalities; Embryonic and Fetal Development; Female; G | 1985 |
Relationship between maternal and fetal fuels and placental glucose transfer in rats with maternal diabetes of varying severity.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; | 1985 |
The effect of diet and insulin on metabolic profiles of women with gestational diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Birth Weight; Blood Glucose; Body Weight; C-Peptide; Circadian Rhythm; | 1985 |
Maturation of fetal rat lung in diabetic pregnancies of graduated severity.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; DNA; Female; Fetal Blood; Fetal Organ Ma | 1985 |
Effect of maternal hyperketonemia in hyperglycemic pregnant ewes and their fetuses.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Female; Fetal Heart; Fetus; Glucose; Heart Rate; Hydr | 1986 |