3-hydroxybutyric acid has been researched along with Pancreatitis in 7 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Pancreatitis: INFLAMMATION of the PANCREAS. Pancreatitis is classified as acute unless there are computed tomographic or endoscopic retrograde cholangiopancreatographic findings of CHRONIC PANCREATITIS (International Symposium on Acute Pancreatitis, Atlanta, 1992). The two most common forms of acute pancreatitis are ALCOHOLIC PANCREATITIS and gallstone pancreatitis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein." | 7.68 | Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992) |
| "To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein." | 3.68 | Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992) |
| "Acute pancreatitis and hyperamylasemia are often seen in patients with acute liver failure (ALF)." | 1.72 | β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb. ( Chen, J; Cui, B; Li, B; Li, X; Liu, J; Liu, L; Shan, C; Sun, N; Sun, W; Xing, H; Xu, Q; Yang, T; Zheng, Y; Zhu, W, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Şahin, E | 1 |
| Bektur Aykanat, NE | 1 |
| Kacar, S | 1 |
| Bagci, R | 1 |
| Sahinturk, V | 1 |
| Zhang, L | 1 |
| Shi, J | 1 |
| Du, D | 1 |
| Niu, N | 1 |
| Liu, S | 1 |
| Yang, X | 1 |
| Lu, P | 1 |
| Shen, X | 1 |
| Shi, N | 1 |
| Yao, L | 1 |
| Zhang, R | 1 |
| Hu, G | 1 |
| Lu, G | 1 |
| Zhu, Q | 1 |
| Zeng, T | 1 |
| Liu, T | 1 |
| Xia, Q | 1 |
| Huang, W | 1 |
| Xue, J | 1 |
| Zheng, Y | 1 |
| Sun, W | 1 |
| Shan, C | 1 |
| Li, B | 1 |
| Liu, J | 1 |
| Xing, H | 1 |
| Xu, Q | 1 |
| Cui, B | 1 |
| Zhu, W | 1 |
| Chen, J | 1 |
| Liu, L | 1 |
| Yang, T | 1 |
| Sun, N | 1 |
| Li, X | 1 |
| Hurrell, FE | 1 |
| Drobatz, KJ | 1 |
| Hess, RS | 1 |
| Hirano, T | 1 |
| Manabe, T | 1 |
| Tobe, T | 1 |
| Larsen, S | 1 |
| Hilsted, J | 1 |
| Philipsen, EK | 1 |
| Tronier, B | 1 |
| Damkjaer Nielsen, M | 1 |
| Worning, H | 1 |
| Fulop, M | 1 |
| Bock, J | 1 |
| Ben-Ezra, J | 1 |
| Antony, M | 1 |
| Danzig, J | 1 |
| Gage, JS | 1 |
7 other studies available for 3-hydroxybutyric acid and Pancreatitis
| Article | Year |
|---|---|
β-Hydroxybutyrate, One of the Three Main Ketone Bodies, Ameliorates Acute Pancreatitis in Rats by Suppressing the NLRP3 Inflammasome Pathway.
Topics: 3-Hydroxybutyric Acid; Animals; Inflammasomes; Male; NLR Family, Pyrin Domain-Containing 3 Protein; | 2021 |
Ketogenesis acts as an endogenous protective programme to restrain inflammatory macrophage activation during acute pancreatitis.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Adolescent; Animals; Ceruletide; China; Disease Models, Animal | 2022 |
β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Animals; Ferroptosis; Hyperamylasemia; Liver Failure, Acute; M | 2022 |
Beta-hydroxybutyrate Concentrations in Dogs with Acute Pancreatitis and Without Diabetes Mellitus.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Animals; Anorexia; Dog Diseases; Dogs; Fasting; Pancreatitis; | 2016 |
Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acute Disease; Adenosine Diphosphate; Adenosine Triphosphate; | 1992 |
The effect of insulin withdrawal on intermediary metabolism in patients with diabetes secondary to chronic pancreatitis.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Chronic Disease; Diabetes Mellitus, Type 1; Epinephrine | 1991 |
Plasma lactate and 3-hydroxybutyrate levels in patients with acute ethanol intoxication.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Adult; Aged; Alcoholic Intoxication; Blood Glucose; Diabetic K | 1986 |