Page last updated: 2024-10-17

3-hydroxybutyric acid and Ovine Diseases

3-hydroxybutyric acid has been researched along with Ovine Diseases in 33 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Research Excerpts

ExcerptRelevanceReference
"Acute acidosis was induced in sheep, and gastrointestinal permeability was assessed by using lactulose as a permeability marker."5.19Experimental acute rumen acidosis in sheep: consequences on clinical, rumen, and gastrointestinal permeability conditions and blood chemistry. ( Ahmed, S; Bani, P; Bertoni, G; Jahan, N; Minuti, A; Piccioli-Cappelli, F; Trevisi, E, 2014)
" On day 140 of pregnancy the ewes were sampled for determination of betaOH-butyrate (BHB), AST, glucose, non-esterified fatty acids (NEFA), total cholesterol (TCH), insulin, T4, T3, cortisol, IGF-1 and leptin."3.73Endocrine characteristics of late pregnant hyperketonaemic ewes and their reproductive performance following the induction of ovarian cyclicity out of the breeding season. ( Cernescu, H; Chilliard, Y; Cseh, S; Dankó, G; Delavaud, C; Gáspárdy, A; Huszenicza, G; Kulcsár, M; Mircu, C; Nikolic, AJ; Rudas, P, 2006)
"Hyperketonemia was successfully achieved, demonstrated by serum BHB concentrations of 3."1.48Potential prophylactic effect of recombinant bovine somatotropin (rbST) in sheep with experimentally induced hyperketonemia. ( Araújo, CASC; Minervino, AHH; Monteiro, BM; Mori, CS; Oliveira, FLC; Ortolani, EL; Rodrigues, FAML; Sousa, RS; Vale, RG, 2018)
"Objective was to investigate if trematode infections predispose ewes to mastitis and/or metritis."1.40Trematode infections in pregnant ewes can predispose to mastitis during the subsequent lactation period. ( Barbagianni, MS; Fthenakis, GC; Gougoulis, DA; Kyriazakis, I; Mavrogianni, VS; Mitsoura, A; Papadopoulos, E; Ptochos, S; Spanos, SA, 2014)
"Hypocalcemia was induced by i."1.32Hypocalcemia reduces endogenous glucose production in hyperketonemic sheep. ( Harmeyer, J; Schlumbohm, C, 2003)
"In the latter the onset of ketosis was earlier in pregnancy (day 143 +/- 7 vs."1.30Spontaneous pregnancy toxaemia (ketosis) in sheep and the role of insulin. ( Bickhardt, K; Fuhrmann, H; Henze, P; Sallmann, HP, 1998)
" congolensis was assessed by the dose-response to experimental inoculation."1.28The effect of energy malnutrition in ruminants on experimental infection with Dermatophilus congolensis. ( Hill, R; How, SJ; Lloyd, DH; Sanders, AB, 1990)
"Propionic acid was used as a possible preventive agent against ketogenesis."1.27Effect of propionic acid on ketogenesis in lactating sheep fed restricted rations or deprived of food. ( Emmanuel, B; Kennelly, JJ, 1984)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19902 (6.06)18.7374
1990's7 (21.21)18.2507
2000's6 (18.18)29.6817
2010's14 (42.42)24.3611
2020's4 (12.12)2.80

Authors

AuthorsStudies
Iqbal, R1
Beigh, SA1
Mir, AQ1
Shaheen, M1
Hussain, SA1
Nisar, M1
Dar, AA1
Khames Mustafa, M1
Shareef Saed, O1
Abdulealah Ismaeel, M1
Dias-Silva, TP1
Abdalla Filho, AL1
Katiki, LM1
Amarante, AFTD1
Abdalla, AL1
Louvandini, H1
Alon, T1
Rosov, A1
Lifshitz, L1
Dvir, H1
Gootwine, E1
Moallem, U1
Bouvier-Muller, J2
Allain, C2
Enjalbert, F2
Farizon, Y1
Portes, D2
Foucras, G2
Rupp, R2
Jones, AK1
Gately, RE1
Kellogg, TD1
Zinn, SA1
Govoni, KE1
Reed, SA1
Araújo, CASC1
Sousa, RS1
Monteiro, BM1
Oliveira, FLC1
Minervino, AHH1
Rodrigues, FAML1
Vale, RG1
Mori, CS1
Ortolani, EL1
Xue, YF1
Guo, CZ1
Hu, F1
Sun, DM1
Liu, JH1
Mao, SY1
Ratanapob, N1
VanLeeuwen, J1
McKenna, S1
Wichtel, M1
Rodriguez-Lecompte, JC1
Menzies, P1
Wichtel, J1
Duehlmeier, R1
Noldt, S1
Ganter, M1
Hornig, KJ1
Byers, SR1
Callan, RJ1
Holt, T1
Field, M1
Han, H1
Mavrogianni, VS1
Papadopoulos, E1
Spanos, SA1
Mitsoura, A1
Ptochos, S1
Gougoulis, DA1
Barbagianni, MS2
Kyriazakis, I1
Fthenakis, GC2
Pichler, M1
Damberger, A1
Schwendenwein, I1
Gasteiner, J1
Drillich, M1
Iwersen, M1
Minuti, A1
Ahmed, S1
Trevisi, E1
Piccioli-Cappelli, F1
Bertoni, G1
Jahan, N1
Bani, P1
Gouletsou, PG1
Valasi, I1
Petridis, IG1
Giannenas, I1
Tabouret, G1
Caubet, C1
Tasca, C1
Da Silva, S1
Cal-Pereyra, LG1
Benech, A1
Acosta-Dibarrat, J1
Martin, MJ1
Abreu, MC1
Perini, S1
González-Montaña, JR1
Penner, GB1
Aschenbach, JR1
Gäbel, G1
Rackwitz, R1
Oba, M1
Al-Qudah, KM1
Schlumbohm, C1
Harmeyer, J1
Kulcsár, M1
Dankó, G1
Delavaud, C1
Mircu, C1
Nikolic, AJ1
Gáspárdy, A1
Cernescu, H1
Chilliard, Y1
Cseh, S1
Rudas, P1
Huszenicza, G1
Phiri, IK1
Phiri, AM1
Harrison, LJ1
Emmanuel, B1
Kennelly, JJ1
Katunguka-Rwakishaya, E2
Henze, P1
Bickhardt, K1
Fuhrmann, H1
Sallmann, HP1
Overton, TR1
Drackley, JK1
Ottemann-Abbamonte, CJ1
Beaulieu, AD1
Clark, JH1
Murray, M2
Holmes, PH2
Osaer, S1
Akinbamijo, OO1
Goossens, B1
Stear, MJ1
Bairden, K1
Duncan, JL1
Eckersall, PD1
Fishwick, G1
Graham, PA1
McKellar, QA1
Mitchell, S1
Parkins, JJ1
Wallace, DS1
Osborne, JM1
Thomas, DL1
White, ME1
Cantley, CE1
Ford, CM1
Heath, MF1
Sanders, AB1
How, SJ1
Lloyd, DH1
Hill, R1
Chandler, KD1
Leury, BJ1
Bird, AR1
Bell, AW1

Trials

2 trials available for 3-hydroxybutyric acid and Ovine Diseases

ArticleYear
Trichostrongylus colubriformis infection in Santa Inês lambs: impact on feed digestibility, blood markers, and nitrogen balance.
    Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria, 2020, Volume: 29, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Cell Count; Blood Proteins; Digestive System; Disease Models,

2020
Experimental acute rumen acidosis in sheep: consequences on clinical, rumen, and gastrointestinal permeability conditions and blood chemistry.
    Journal of animal science, 2014, Volume: 92, Issue:9

    Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Blood Glucose; Ceruloplasmin; Cross-Over Studies; Gastroin

2014

Other Studies

31 other studies available for 3-hydroxybutyric acid and Ovine Diseases

ArticleYear
Evaluation of metabolic and oxidative profile in ovine pregnancy toxemia and to determine their association with diagnosis and prognosis of disease.
    Tropical animal health and production, 2022, Oct-10, Volume: 54, Issue:6

    Topics: 3-Hydroxybutyric Acid; Albumins; Animals; Aspartic Acid; Butyric Acid; Calcium; Catalase; Cholestero

2022
Clinical and Biochemical Study of Pregnancy Toxemia in Iraqi Ewes.
    Archives of Razi Institute, 2023, Volume: 78, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Iraq; Pre-Eclamps

2023
The distinctive short-term response of late-pregnant prolific ewes to propylene glycol or glycerol drenching.
    Journal of dairy science, 2020, Volume: 103, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Dietary Supplements; Fatty Acids, Nonesterified; Fema

2020
Somatic cell count-based selection reduces susceptibility to energy shortage during early lactation in a sheep model.
    Journal of dairy science, 2018, Volume: 101, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Body Weight; Cell Count; Energy Metabolism; Fatty Ac

2018
Evaluation of the Nova Vet Meter for sheep-side monitoring of β-hydroxybutyric acid (BHBA) and description of ewe BHBA during late gestation in three flocks from the Northeastern U.S.
    Research in veterinary science, 2018, Volume: 118

    Topics: 3-Hydroxybutyric Acid; Animals; Female; Ketosis; Parturition; Pregnancy; Pregnancy, Animal; ROC Curv

2018
Potential prophylactic effect of recombinant bovine somatotropin (rbST) in sheep with experimentally induced hyperketonemia.
    Research in veterinary science, 2018, Volume: 119

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Female; Growth Hormone; Insulin; Insulin-Like Growth Factor

2018
Molecular mechanisms of lipid metabolism disorder in livers of ewes with pregnancy toxemia.
    Animal : an international journal of animal bioscience, 2019, Volume: 13, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Behavior, Animal; Cholesterol; Energy Metabolism; Fatty Acids, Nones

2019
Evaluation of the Precision Xtra meter for monitoring blood β-hydroxybutyrate concentrations in late-gestation ewes.
    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc, 2019, Volume: 31, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Diagnostic Tests, Routine; Female; Ketosis; Pregnancy; Sheep; Sheep

2019
Pancreatic insulin release and peripheral insulin sensitivity in German black headed mutton and Finish Landrace ewes: evaluation of the role of insulin resistance in the susceptibility to ovine pregnancy toxemia.
    Domestic animal endocrinology, 2013, Volume: 44, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Genetic Predispos

2013
Evaluation of a point-of-care glucose and β-hydroxybutyrate meter operated in various environmental conditions in prepartum and postpartum sheep.
    American journal of veterinary research, 2013, Volume: 74, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Female; Point-of-Care Systems; Postpartum Period; Pre

2013
Trematode infections in pregnant ewes can predispose to mastitis during the subsequent lactation period.
    Research in veterinary science, 2014, Volume: 96, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Feces; Female; Greece; Incidence; Lactation; Mammary Glands, Animal;

2014
Thresholds of whole-blood β-hydroxybutyrate and glucose concentrations measured with an electronic hand-held device to identify ovine hyperketonemia.
    Journal of dairy science, 2014, Volume: 97, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Austria; Blood Chemical Analysis; Blood Glucose; Blood Specimen Coll

2014
Ultrasonographic findings in the ovine udder during lactogenesis in healthy ewes or ewes with pregnancy toxaemia.
    The Journal of dairy research, 2015, Volume: 82, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Blood Glucose; Female; Hemodynamics; Lactation; Mammary

2015
Response to dietary-induced energy restriction in dairy sheep divergently selected for resistance or susceptibility to mastitis.
    Journal of dairy science, 2016, Volume: 99, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Diet; Disease Susceptibility; Energy Intake; Energy Met

2016
Evaluation of a fibrate, specific stimulant of PPARα, as a therapeutic alternative to the treatment of clinical ovine pregnancy toxaemia.
    Journal of veterinary pharmacology and therapeutics, 2016, Volume: 39, Issue:5

    Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animals; Blood Glucose; Female; Fibric Acids; PPAR alph

2016
Epithelial capacity for apical uptake of short chain fatty acids is a key determinant for intraruminal pH and the susceptibility to subacute ruminal acidosis in sheep.
    The Journal of nutrition, 2009, Volume: 139, Issue:9

    Topics: 3-Hydroxybutyric Acid; Acetates; Acidosis; Animals; Bicarbonates; Biological Transport; Butyrates; E

2009
Oxidant and antioxidant profile of hyperketonemic ewes affected by pregnancy toxemia.
    Veterinary clinical pathology, 2011, Volume: 40, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Blood Glucose; Catalase; Female; Glutathione Peroxidas

2011
Hypocalcemia reduces endogenous glucose production in hyperketonemic sheep.
    Journal of dairy science, 2003, Volume: 86, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Calcium; Energy Metabolism; Female; Glucose; Hypocalc

2003
Endocrine characteristics of late pregnant hyperketonaemic ewes and their reproductive performance following the induction of ovarian cyclicity out of the breeding season.
    Acta veterinaria Hungarica, 2006, Volume: 54, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Female; Gona

2006
The serum glucose and beta-hydroxybutyrate levels in sheep with experimental Fasciola hepatica and Fasciola gigantica infection.
    Veterinary parasitology, 2007, Feb-28, Volume: 143, Issue:3-4

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Fasciola; Fasciola hepatica; Fascioliasis; gamma-Glut

2007
Effect of propionic acid on ketogenesis in lactating sheep fed restricted rations or deprived of food.
    Journal of dairy science, 1984, Volume: 67, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Diet; Fatty Acids, Nonesteri

1984
The influence of dietary protein on some blood biochemical parameters in Scottish blackface sheep experimentally infected with Trypanosoma congolense.
    Veterinary parasitology, 1997, Volume: 68, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Appetite; Blood Glucose; Blood Proteins; Cholesterol; Diet, Protein-

1997
Spontaneous pregnancy toxaemia (ketosis) in sheep and the role of insulin.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1998, Volume: 45, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Female; Hydroxybutyrates; Hypoglycemic Agents; Insuli

1998
Metabolic adaptation to experimentally increased glucose demand in ruminants.
    Journal of animal science, 1998, Volume: 76, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Urea Nitrogen; Disease Models, Animal; Fatty Ac

1998
The influence of energy intake on some blood biochemical parameters in Scottish Blackface sheep infected with Trypanosoma congolense.
    Veterinary parasitology, 1999, Volume: 84, Issue:1-2

    Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Blood; Blood Glucose; Blood Proteins; Body Weight; Chol

1999
Some biochemical changes following Trypanosoma congolense infection in Djallonké ewe lambs and breeding ewes fed on two levels of nutrition.
    Acta tropica, 2000, Mar-25, Volume: 75, Issue:2

    Topics: 3-Hydroxybutyric Acid; Age Factors; Animal Nutritional Physiological Phenomena; Animals; Blood Gluco

2000
The influence of relative resistance and urea-supplementation on deliberate infection with Teladorsagia circumcincta during winter.
    Veterinary parasitology, 2000, Dec-20, Volume: 94, Issue:1-2

    Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Blood Glucose; Blood Proteins; Dietary Supplements; Dis

2000
Insulin-like growth factor-I levels and gene expression in ovine hereditary chondrodysplasia (spider lamb syndrome).
    Domestic animal endocrinology, 1992, Volume: 9, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blotting, Northern; Blotting, Western; Exostoses, Mul

1992
Serum fructosamine in ovine pregnancy toxaemia: a possible prognostic index.
    The Veterinary record, 1991, Jun-01, Volume: 128, Issue:22

    Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Female; Fructosamine; Hexosamines; Hydroxybutyrates; Pre

1991
The effect of energy malnutrition in ruminants on experimental infection with Dermatophilus congolensis.
    Journal of comparative pathology, 1990, Volume: 103, Issue:4

    Topics: 3-Hydroxybutyric Acid; Actinomycetales Infections; Animals; Cell Division; Energy Metabolism; Hydrox

1990
Effects of undernutrition and exercise during late pregnancy on uterine, fetal and uteroplacental metabolism in the ewe.
    The British journal of nutrition, 1985, Volume: 53, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Fatty Acids, Nonesterified; Female; Fetus; Glucose; Hyd

1985