3-hydroxybutyric acid has been researched along with Neurodegenerative Diseases in 5 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Neurodegenerative Diseases: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is widely accepted that ketosis (increased blood ketone body levels, e." | 2.72 | Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases. ( Ari, C; Brunner, B; Kovács, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lehto, A | 1 |
| Koch, K | 1 |
| Barnstorf-Brandes, J | 1 |
| Viel, C | 1 |
| Fuchs, M | 1 |
| Klein, J | 1 |
| Jiang, Z | 3 |
| Yin, X | 3 |
| Wang, M | 3 |
| Wang, Y | 3 |
| Li, F | 3 |
| Gao, Y | 3 |
| Han, G | 3 |
| Gao, Z | 3 |
| Wang, Z | 3 |
| Soto-Mota, A | 1 |
| Norwitz, NG | 1 |
| Clarke, K | 1 |
| Kovács, Z | 1 |
| Brunner, B | 1 |
| Ari, C | 1 |
| Veech, RL | 1 |
| Chance, B | 1 |
| Kashiwaya, Y | 1 |
| Lardy, HA | 1 |
| Cahill, GF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Safety and Tolerability of Exogenous Ketosis Induced by Free Beta-hydroxybutyrate.[NCT05584371] | 30 participants (Anticipated) | Interventional | 2022-10-31 | Recruiting | |||
| Comparison Between Endogenous and Exogenous Ketosis in Patients With Non-ischemic Chronic Heart Failure With Reduced Ejection Fraction[NCT04921293] | 18 participants (Anticipated) | Interventional | 2023-06-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for 3-hydroxybutyric acid and Neurodegenerative Diseases
| Article | Year |
|---|---|
Why a d-β-hydroxybutyrate monoester?
Topics: 3-Hydroxybutyric Acid; Diabetes Mellitus; Diet, Ketogenic; Dietary Supplements; Epilepsy; Fasting; H | 2020 |
Why a d-β-hydroxybutyrate monoester?
Topics: 3-Hydroxybutyric Acid; Diabetes Mellitus; Diet, Ketogenic; Dietary Supplements; Epilepsy; Fasting; H | 2020 |
Why a d-β-hydroxybutyrate monoester?
Topics: 3-Hydroxybutyric Acid; Diabetes Mellitus; Diet, Ketogenic; Dietary Supplements; Epilepsy; Fasting; H | 2020 |
Why a d-β-hydroxybutyrate monoester?
Topics: 3-Hydroxybutyric Acid; Diabetes Mellitus; Diet, Ketogenic; Dietary Supplements; Epilepsy; Fasting; H | 2020 |
Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases.
Topics: 3-Hydroxybutyric Acid; Aging; Alzheimer Disease; Diet, Ketogenic; Dietary Supplements; Epigenomics; | 2021 |
Ketone bodies, potential therapeutic uses.
Topics: 3-Hydroxybutyric Acid; Animals; Brain; Energy Metabolism; Epilepsy; Fasting; Humans; Ketone Bodies; | 2001 |
2 other studies available for 3-hydroxybutyric acid and Neurodegenerative Diseases
| Article | Year |
|---|---|
ß-Hydroxybutyrate Improves Mitochondrial Function After Transient Ischemia in the Mouse.
Topics: 3-Hydroxybutyric Acid; Animals; Citrates; Hydroxybutyrates; Ischemia; Ketone Bodies; Mice; Mitochond | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |
β-Hydroxybutyrate alleviates pyroptosis in MPP
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3-Hydroxybutyric Acid; An | 2022 |