3-hydroxybutyric acid has been researched along with Myocardial Ischemia in 9 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Myocardial Ischemia: A disorder of cardiac function caused by insufficient blood flow to the muscle tissue of the heart. The decreased blood flow may be due to narrowing of the coronary arteries (CORONARY ARTERY DISEASE), to obstruction by a thrombus (CORONARY THROMBOSIS), or less commonly, to diffuse narrowing of arterioles and other small vessels within the heart. Severe interruption of the blood supply to the myocardial tissue may result in necrosis of cardiac muscle (MYOCARDIAL INFARCTION).
| Excerpt | Relevance | Reference |
|---|---|---|
| "As L-carnitine plays a pivotal role in the balanced metabolism of fatty acids and carbohydrates, this study was carried out to investigate whether long-term mildronate treatment could influence glucose levels and prevent diabetic complications in an experimental model of type 2 diabetes in Goto-Kakizaki (GK) rats." | 1.35 | Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats. ( Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Skapare, E; Svalbe, B; Vilskersts, R; Zvejniece, L, 2009) |
| "Glycogen depletion by anoxia or glucagon before ischemia impaired recovery." | 1.29 | Metabolic recovery of isolated working rat heart after brief global ischemia. ( Goodwin, GW; Taegtmeyer, H, 1994) |
| " A plasma glucose level of 300 mg dl-1 was not achieved until the total dosage of insulin amounted to 91,580 units at hour 25." | 1.28 | Transient extreme insulin resistance in shock during diabetic ketoacidosis. ( Hasumi, S; Omori, Y; Shimizu, Y; Wasada, T; Yokoyama, H; Yoshino, H, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Lindsay, RT | 1 |
| Dieckmann, S | 1 |
| Krzyzanska, D | 1 |
| Manetta-Jones, D | 1 |
| West, JA | 1 |
| Castro, C | 1 |
| Griffin, JL | 1 |
| Murray, AJ | 1 |
| Liepinsh, E | 1 |
| Vilskersts, R | 1 |
| Zvejniece, L | 1 |
| Svalbe, B | 1 |
| Skapare, E | 1 |
| Kuka, J | 1 |
| Cirule, H | 1 |
| Grinberga, S | 1 |
| Kalvinsh, I | 1 |
| Dambrova, M | 1 |
| Monti, LD | 1 |
| Setola, E | 1 |
| Fragasso, G | 1 |
| Camisasca, RP | 1 |
| Lucotti, P | 1 |
| Galluccio, E | 1 |
| Origgi, A | 1 |
| Margonato, A | 1 |
| Piatti, P | 1 |
| Amark, K | 2 |
| Berggren, H | 1 |
| Björk, K | 1 |
| Ekroth, A | 1 |
| Ekroth, R | 2 |
| Nilsson, K | 2 |
| Sunnegårdh, J | 2 |
| Söderberg, B | 1 |
| Goodwin, GW | 2 |
| Taegtmeyer, H | 2 |
| Geraldes, CF | 1 |
| Castro, MM | 1 |
| Sherry, AD | 1 |
| Ramasamy, R | 1 |
| Chen, TM | 1 |
| Guthrie, PH | 1 |
| Yokoyama, H | 1 |
| Wasada, T | 1 |
| Shimizu, Y | 1 |
| Yoshino, H | 1 |
| Hasumi, S | 1 |
| Omori, Y | 1 |
2 trials available for 3-hydroxybutyric acid and Myocardial Ischemia
| Article | Year |
|---|---|
Metabolic and endothelial effects of trimetazidine on forearm skeletal muscle in patients with type 2 diabetes and ischemic cardiomyopathy.
Topics: 3-Hydroxybutyric Acid; Aged; Blood Glucose; Citric Acid; Cross-Over Studies; Cyclic GMP; Diabetes Me | 2006 |
Myocardial metabolism is better preserved after blood cardioplegia in infants.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Aorta; Bicarbonates; Blood; Blood Glucose; Calcium Chloride; Car | 2006 |
7 other studies available for 3-hydroxybutyric acid and Myocardial Ischemia
| Article | Year |
|---|---|
β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery.
Topics: 3-Hydroxybutyric Acid; Animals; Chromatography, Liquid; Citric Acid Cycle; Heart; Hydroxymethylgluta | 2021 |
Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.
Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animals; Blood Glucose; Cardiovascular Agents; Carnitin | 2009 |
Myocardial substrates in children with congenital heart disease: relationship to substrate supply, age, growth and desaturation.
Topics: 3-Hydroxybutyric Acid; Adolescent; Age Factors; Analysis of Variance; Blood Chemical Analysis; Blood | 2007 |
Metabolic recovery of isolated working rat heart after brief global ischemia.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Fasting; Glucose-6-Phosphate; Glucosephospha | 1994 |
Influence of vanadate on glycolysis, intracellular sodium, and pH in perfused rat hearts.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Energy Metabolism; Glucose; Glycogen; Glycol | 1997 |
Effects of insulin on glucose uptake by rat hearts during and after coronary flow reduction.
Topics: 3-Hydroxybutyric Acid; Animals; Biological Transport; Caprylates; Citrates; Coronary Circulation; Gl | 1997 |
Transient extreme insulin resistance in shock during diabetic ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Aged; Blood Glucose; Diabetic Ketoacidosis; Erythrocytes | 1992 |