3-hydroxybutyric acid has been researched along with Muscular Atrophy in 2 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Muscular Atrophy: Derangement in size and number of muscle fibers occurring with aging, reduction in blood supply, or following immobilization, prolonged weightlessness, malnutrition, and particularly in denervation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There were 100 adult trauma patients with Injury Severity Score (ISS) >18 were enrolled in this prospective, randomized, blinded study." | 2.73 | Beta-hydroxy-beta-methylbutyrate supplementation in critically ill trauma patients. ( Barber, A; Coates, JE; Fildes, JJ; Frisch, DA; Kuhls, DA; MacIntyre, AD; Musngi, MD; Nielson, J; Rathmacher, JA, 2007) |
| "The 'obesity paradox' of critical illness refers to better survival with a higher body mass index." | 1.46 | Premorbid obesity, but not nutrition, prevents critical illness-induced muscle wasting and weakness. ( De Bock, K; Derde, S; Dufour, T; Goossens, C; Güiza, F; Hermans, G; Janssens, T; Langouche, L; Marques, MB; Thiessen, SE; Van den Berghe, G; Vander Perre, S; Vanhorebeek, I, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goossens, C | 1 |
| Marques, MB | 1 |
| Derde, S | 1 |
| Vander Perre, S | 1 |
| Dufour, T | 1 |
| Thiessen, SE | 1 |
| Güiza, F | 1 |
| Janssens, T | 1 |
| Hermans, G | 1 |
| Vanhorebeek, I | 1 |
| De Bock, K | 1 |
| Van den Berghe, G | 1 |
| Langouche, L | 1 |
| Kuhls, DA | 1 |
| Rathmacher, JA | 1 |
| Musngi, MD | 1 |
| Frisch, DA | 1 |
| Nielson, J | 1 |
| Barber, A | 1 |
| MacIntyre, AD | 1 |
| Coates, JE | 1 |
| Fildes, JJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Strategies to Reduce Organic Muscle Atrophy in the Intensive Care Unit (STROMA-ICU)[NCT02773771] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2017-01-31 | Withdrawn (stopped due to Per IRB submission history, submission declined and withdrawn. PI no longer at institution.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for 3-hydroxybutyric acid and Muscular Atrophy
| Article | Year |
|---|---|
Beta-hydroxy-beta-methylbutyrate supplementation in critically ill trauma patients.
Topics: 3-Hydroxybutyric Acid; Adult; Arginine; Biomarkers; Enteral Nutrition; Female; Glutamine; Humans; Ma | 2007 |
1 other study available for 3-hydroxybutyric acid and Muscular Atrophy
| Article | Year |
|---|---|
Premorbid obesity, but not nutrition, prevents critical illness-induced muscle wasting and weakness.
Topics: 3-Hydroxybutyric Acid; Aged; Animals; Body Composition; Critical Illness; Fasting; Fatty Acids; Fema | 2017 |