3-hydroxybutyric acid has been researched along with Muscular Atrophy, Spinal in 1 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Proximal spinal muscular atrophy (SMA) is a leading genetic cause of infant death." | 1.36 | Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. ( Butchbach, ME; Lorson, CL; Marston, J; McCrone, JT; Rhoades, S; Rose, FF; Sinnott, R, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Butchbach, ME | 1 |
| Rose, FF | 1 |
| Rhoades, S | 1 |
| Marston, J | 1 |
| McCrone, JT | 1 |
| Sinnott, R | 1 |
| Lorson, CL | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Prospective Evaluation of Infants With Spinal Muscular Atrophy: SPOT SMA[NCT02831296] | 1,000 participants (Anticipated) | Observational [Patient Registry] | 2016-02-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 other study available for 3-hydroxybutyric acid and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diet; Disease Models, Animal; Female; Male; Mice; Mic | 2010 |