3-hydroxybutyric acid has been researched along with Mitochondrial Diseases in 4 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It is widely accepted that ketosis (increased blood ketone body levels, e." | 2.72 | Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases. ( Ari, C; Brunner, B; Kovács, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kovács, Z | 1 |
| Brunner, B | 1 |
| Ari, C | 1 |
| Semeraro, M | 1 |
| Boenzi, S | 1 |
| Carrozzo, R | 1 |
| Diodato, D | 1 |
| Martinelli, D | 1 |
| Olivieri, G | 1 |
| Antonetti, G | 1 |
| Sacchetti, E | 1 |
| Catesini, G | 1 |
| Rizzo, C | 1 |
| Dionisi-Vici, C | 1 |
| Paoli, A | 1 |
| Bianco, A | 1 |
| Damiani, E | 1 |
| Bosco, G | 1 |
| Kabiraj, P | 1 |
| Pal, R | 1 |
| Varela-Ramirez, A | 1 |
| Miranda, M | 1 |
| Narayan, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized-controlled Study for Evaluation of Ketogenic Metabolic Nutritional Pattern in Subjects With High-frequency Episodic Migraine[NCT04360148] | 58 participants (Anticipated) | Interventional | 2020-02-06 | Active, not recruiting | |||
| Ketogenic Diet Interventions in Parkinson's Disease: Safeguarding the Gut Microbiome[NCT05469997] | 50 participants (Anticipated) | Interventional | 2023-01-31 | Not yet recruiting | |||
| Ketogenic Diet in McArdle Disease: a Multicentric Single Blind Controlled Trial[NCT04292938] | 16 participants (Actual) | Interventional | 2019-03-25 | Completed | |||
| The Safety and Effects on Whole Organism of Low Energy Ketogenic Diet for Weight Loss in Obese Subjects[NCT03338452] | 38 participants (Actual) | Interventional | 2017-03-18 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for 3-hydroxybutyric acid and Mitochondrial Diseases
| Article | Year |
|---|---|
Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases.
Topics: 3-Hydroxybutyric Acid; Aging; Alzheimer Disease; Diet, Ketogenic; Dietary Supplements; Epigenomics; | 2021 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
2 other studies available for 3-hydroxybutyric acid and Mitochondrial Diseases
| Article | Year |
|---|---|
The urinary organic acids profile in single large-scale mitochondrial DNA deletion disorders.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase, Long-Chain; Adolescent; Child; Child, Preschool; Cong | 2018 |
Nitrosative stress mediated misfolded protein aggregation mitigated by Na-D-β-hydroxybutyrate intervention.
Topics: 3-Hydroxybutyric Acid; Apoptosis; Carrier Proteins; Caspases; Cell Line, Tumor; Dopaminergic Neurons | 2012 |