3-hydroxybutyric acid has been researched along with Metabolic Diseases in 10 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Metabolic Diseases: Generic term for diseases caused by an abnormal metabolic process. It can be congenital due to inherited enzyme abnormality (METABOLISM, INBORN ERRORS) or acquired due to disease of an endocrine organ or failure of a metabolically important organ such as the liver. (Stedman, 26th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Subclinical ketosis (serum BHB >1200 to 1400 micromol/l) in the first or second week after calving is associated with increased risk of DA, metritis, clinical ketosis, endometritis, prolonged postpartum anovulation, increased severity of mastitis, and lower milk production in early lactation." | 2.46 | Monitoring metabolic health of dairy cattle in the transition period. ( LeBlanc, S, 2010) |
| "Metabolic diseases included clinical ketosis (KET) and displaced abomasum (DA); fertility disorders were metritis (MET) and retained placenta (RP); and disease indicators were fat-to-protein ratio, milk β-hydroxybutyrate, and body condition score (BCS) in the first lactation." | 1.43 | Multiple-trait estimates of genetic parameters for metabolic disease traits, fertility disorders, and their predictors in Canadian Holsteins. ( Jamrozik, J; Kistemaker, GJ; Koeck, A; Miglior, F, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Almughlliq, FB | 1 |
| Koh, YQ | 1 |
| Peiris, HN | 1 |
| Vaswani, K | 1 |
| Holland, O | 1 |
| Meier, S | 1 |
| Roche, JR | 1 |
| Burke, CR | 1 |
| Crookenden, MA | 1 |
| Arachchige, BJ | 1 |
| Reed, S | 1 |
| Mitchell, MD | 1 |
| Heimer, J | 1 |
| Gascho, D | 1 |
| Madea, B | 1 |
| Steuer, A | 1 |
| Martinez, RM | 1 |
| Thali, MJ | 1 |
| Zoelch, N | 1 |
| Wang, J | 1 |
| Zhu, X | 1 |
| She, G | 1 |
| Kong, Y | 1 |
| Guo, Y | 1 |
| Wang, Z | 1 |
| Liu, G | 1 |
| Zhao, B | 1 |
| Gross, JJ | 1 |
| Bruckmaier, RM | 1 |
| Ospina, PA | 1 |
| McArt, JA | 1 |
| Overton, TR | 1 |
| Stokol, T | 1 |
| Nydam, DV | 1 |
| Liboreiro, DN | 1 |
| Machado, KS | 1 |
| Silva, PR | 1 |
| Maturana, MM | 1 |
| Nishimura, TK | 1 |
| Brandão, AP | 1 |
| Endres, MI | 1 |
| Chebel, RC | 1 |
| Jamrozik, J | 1 |
| Koeck, A | 1 |
| Kistemaker, GJ | 1 |
| Miglior, F | 1 |
| LeBlanc, S | 1 |
| Taha, AY | 1 |
| Gao, F | 1 |
| Ramadan, E | 1 |
| Cheon, Y | 1 |
| Rapoport, SI | 1 |
| Kim, HW | 1 |
| Morris, AA | 1 |
| Thekekara, A | 1 |
| Wilks, Z | 1 |
| Clayton, PT | 1 |
| Leonard, JV | 1 |
| Aynsley-Green, A | 1 |
3 reviews available for 3-hydroxybutyric acid and Metabolic Diseases
| Article | Year |
|---|---|
Review: Metabolic challenges in lactating dairy cows and their assessment via established and novel indicators in milk.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Biomarkers; Cattle; Cattle Diseases; Diet; Fatty Acids; Fe | 2019 |
Using nonesterified fatty acids and β-hydroxybutyrate concentrations during the transition period for herd-level monitoring of increased risk of disease and decreased reproductive and milking performance.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Biomarkers; Cattle; Cattle Diseases; Energy Metaboli | 2013 |
Monitoring metabolic health of dairy cattle in the transition period.
Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Dairying; Diet; Early Diagnosis; Energy Met | 2010 |
7 other studies available for 3-hydroxybutyric acid and Metabolic Diseases
| Article | Year |
|---|---|
Circulating exosomes may identify biomarkers for cows at risk for metabolic dysfunction.
Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Cattle; Endometrium; Epithelial Cells; Exosomes; Female; | 2019 |
Comparison of the beta-hydroxybutyrate, glucose, and lactate concentrations derived from postmortem proton magnetic resonance spectroscopy and biochemical analysis for the diagnosis of fatal metabolic disorders.
Topics: 3-Hydroxybutyric Acid; Autopsy; Biomarkers; Glucose; Humans; Lactic Acid; Lateral Ventricles; Metabo | 2020 |
Serum hepatokines in dairy cows: periparturient variation and changes in energy-related metabolic disorders.
Topics: 3-Hydroxybutyric Acid; Angiopoietin-Like Protein 4; Animals; Cattle; Cattle Diseases; Fatty Acids, N | 2018 |
Characterization of peripartum rumination and activity of cows diagnosed with metabolic and uterine diseases.
Topics: 3-Hydroxybutyric Acid; Animals; Calcium; Cattle; Cattle Diseases; Digestion; Fatty Acids, Nonesterif | 2015 |
Multiple-trait estimates of genetic parameters for metabolic disease traits, fertility disorders, and their predictors in Canadian Holsteins.
Topics: 3-Hydroxybutyric Acid; Animals; Bayes Theorem; Canada; Cattle; Cattle Diseases; Female; Fertility; G | 2016 |
Upregulated expression of brain enzymatic markers of arachidonic and docosahexaenoic acid metabolism in a rat model of the metabolic syndrome.
Topics: 3-Hydroxybutyric Acid; Animals; Arachidonic Acid; Blood Glucose; Brain; Brain-Derived Neurotrophic F | 2012 |
Evaluation of fasts for investigating hypoglycaemia or suspected metabolic disease.
Topics: 3-Hydroxybutyric Acid; Age Distribution; Child; Child, Preschool; Evaluation Studies as Topic; Fasti | 1996 |