3-hydroxybutyric acid has been researched along with MS (Multiple Sclerosis) in 7 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Here, we report on the role of haptoglobin (Hp), whose expression depends on the synthesis of interleukin 6 (IL-6), related to the pathogenesis of multiple sclerosis (MS), as a possible marker of muscle improvement achieved after treatment with the polyphenol epigallocatechin gallate (EGCG) and an increase in the ketone body beta-hydroxybutyrate (BHB) in the blood." | 8.02 | Role of Haptoglobin as a Marker of Muscular Improvement in Patients with Multiple Sclerosis after Administration of Epigallocatechin Gallate and Increase of Beta-Hydroxybutyrate in the Blood: A Pilot Study. ( Benlloch, M; de la Rubia Ortí, JE; Escribá-Alepuz, J; Franco-Martinez, L; Platero, JL; Sancho-Castillo, S; Tvarijonaviciute, A, 2021) |
| "Here, we report on the role of haptoglobin (Hp), whose expression depends on the synthesis of interleukin 6 (IL-6), related to the pathogenesis of multiple sclerosis (MS), as a possible marker of muscle improvement achieved after treatment with the polyphenol epigallocatechin gallate (EGCG) and an increase in the ketone body beta-hydroxybutyrate (BHB) in the blood." | 4.02 | Role of Haptoglobin as a Marker of Muscular Improvement in Patients with Multiple Sclerosis after Administration of Epigallocatechin Gallate and Increase of Beta-Hydroxybutyrate in the Blood: A Pilot Study. ( Benlloch, M; de la Rubia Ortí, JE; Escribá-Alepuz, J; Franco-Martinez, L; Platero, JL; Sancho-Castillo, S; Tvarijonaviciute, A, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 3 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, JE | 1 |
| Titcomb, TJ | 1 |
| Bisht, B | 1 |
| Rubenstein, LM | 1 |
| Louison, R | 1 |
| Wahls, TL | 1 |
| Benlloch, M | 2 |
| Cuerda Ballester, M | 1 |
| Drehmer, E | 1 |
| Platero, JL | 2 |
| Carrera-Juliá, S | 1 |
| López-Rodríguez, MM | 1 |
| Ceron, JJ | 1 |
| Tvarijonaviciute, A | 2 |
| Navarro, MÁ | 1 |
| Moreno, ML | 1 |
| de la Rubia Ortí, JE | 2 |
| Franco-Martinez, L | 1 |
| Escribá-Alepuz, J | 1 |
| Sancho-Castillo, S | 1 |
| Kugelberg, E | 1 |
| Offermanns, S | 1 |
| Schwaninger, M | 1 |
| Netea, MG | 1 |
| Joosten, LA | 1 |
| Groß, CJ | 1 |
| Groß, O | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of an Online Course Designed to Support the Adoption of Healthier Diet and Self-Care Routines in Multiple Sclerosis Patients[NCT05057676] | 80 participants (Anticipated) | Interventional | 2021-12-01 | Recruiting | |||
| Efficacy of Diet on Quality of Life in Multiple Sclerosis[NCT05007483] | 156 participants (Anticipated) | Interventional | 2022-02-10 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 3-hydroxybutyric acid and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Nutritional or pharmacological activation of HCA(2) ameliorates neuroinflammation.
Topics: 3-Hydroxybutyric Acid; Adenylyl Cyclases; Animals; Brain; Brain Ischemia; Diet, Ketogenic; Dimethyl | 2015 |
2 trials available for 3-hydroxybutyric acid and MS (Multiple Sclerosis)
4 other studies available for 3-hydroxybutyric acid and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
Role of Haptoglobin as a Marker of Muscular Improvement in Patients with Multiple Sclerosis after Administration of Epigallocatechin Gallate and Increase of Beta-Hydroxybutyrate in the Blood: A Pilot Study.
Topics: 3-Hydroxybutyric Acid; Adult; Biomarkers; Catechin; Female; Haptoglobins; Humans; Interleukin-6; Mal | 2021 |
Inflammasome: starving inflammation.
Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Periodic Syndromes | 2015 |
Inflammasome inhibition: putting out the fire.
Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Periodic Syndromes | 2015 |
The Nlrp3 inflammasome admits defeat.
Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Periodic Syndromes | 2015 |