3-hydroxybutyric acid has been researched along with MELAS Syndrome in 2 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
MELAS Syndrome: A mitochondrial disorder characterized by focal or generalized seizures, episodes of transient or persistent neurologic dysfunction resembling strokes, and ragged-red fibers on muscle biopsy. Affected individuals tend to be normal at birth through early childhood, then experience growth failure, episodic vomiting, and recurrent cerebral insults resulting in visual loss and hemiparesis. The cortical lesions tend to occur in the parietal and occipital lobes and are not associated with vascular occlusion. VASCULAR HEADACHE is frequently associated and the disorder tends to be familial. (From Joynt, Clinical Neurology, 1992, Ch56, p117)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The diagnosis of MELAS mutation was reinforced by the absence of an identifiable mutation in the X-linked G4." | 1.31 | Barth's syndrome-like disorder: a new phenotype with a maternally inherited A3243G substitution of mitochondrial DNA (MELAS mutation). ( Angaroni, C; Argaraña, C; Bacman, S; Civallero, G; De Kremer, RD; Depetris-Boldini, C; Giner-Ayala, A; Gonzalez, I; Guelbert, N; Hliba, E; Johnston, J; Juaneda, E; Kelley, RI; Latini, A; Noher de Halac, I; Oller-Ramírez, A; Paschini-Capra, A; Proujansky, R; Theaux, RA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reed, EM | 1 |
| Swanson, AA | 1 |
| Roden, AC | 1 |
| Lin, PT | 1 |
| De Kremer, RD | 1 |
| Paschini-Capra, A | 1 |
| Bacman, S | 1 |
| Argaraña, C | 1 |
| Civallero, G | 1 |
| Kelley, RI | 1 |
| Guelbert, N | 1 |
| Latini, A | 1 |
| Noher de Halac, I | 1 |
| Giner-Ayala, A | 1 |
| Johnston, J | 1 |
| Proujansky, R | 1 |
| Gonzalez, I | 1 |
| Depetris-Boldini, C | 1 |
| Oller-Ramírez, A | 1 |
| Angaroni, C | 1 |
| Theaux, RA | 1 |
| Hliba, E | 1 |
| Juaneda, E | 1 |
2 other studies available for 3-hydroxybutyric acid and MELAS Syndrome
| Article | Year |
|---|---|
Sudden Unexpected Death in MELAS Syndrome Due to Diabetic Ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Acetone; Adult; Brain; Death, Sudden; Diabetic Ketoacidosis; Glucose; Humans; | 2020 |
Barth's syndrome-like disorder: a new phenotype with a maternally inherited A3243G substitution of mitochondrial DNA (MELAS mutation).
Topics: 3-Hydroxybutyric Acid; Acids; Argentina; Biopsy; Child, Preschool; DNA, Mitochondrial; Electron Tran | 2001 |