3-hydroxybutyric acid has been researched along with Liver Failure, Acute in 4 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute pancreatitis and hyperamylasemia are often seen in patients with acute liver failure (ALF)." | 1.72 | β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb. ( Chen, J; Cui, B; Li, B; Li, X; Liu, J; Liu, L; Shan, C; Sun, N; Sun, W; Xing, H; Xu, Q; Yang, T; Zheng, Y; Zhu, W, 2022) |
| "Hepatocyte regeneration in acute hepatic failure is essential for recovery, but requires a large amount of energy." | 1.29 | Plasma exchange and the arterial blood ketone body ratio in patients with acute hepatic failure. ( Maeda, T; Onishi, S; Saibara, T; Yamamoto, Y, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zheng, Y | 1 |
| Sun, W | 1 |
| Shan, C | 1 |
| Li, B | 1 |
| Liu, J | 1 |
| Xing, H | 1 |
| Xu, Q | 1 |
| Cui, B | 1 |
| Zhu, W | 1 |
| Chen, J | 1 |
| Liu, L | 1 |
| Yang, T | 1 |
| Sun, N | 1 |
| Li, X | 1 |
| Pawlak, M | 1 |
| Baugé, E | 1 |
| Lalloyer, F | 1 |
| Lefebvre, P | 1 |
| Staels, B | 1 |
| Feng, B | 1 |
| Wu, SM | 1 |
| Lv, S | 1 |
| Liu, F | 1 |
| Chen, HS | 1 |
| Gao, Y | 1 |
| Dong, FT | 1 |
| Wei, L | 1 |
| Saibara, T | 1 |
| Maeda, T | 1 |
| Onishi, S | 1 |
| Yamamoto, Y | 1 |
4 other studies available for 3-hydroxybutyric acid and Liver Failure, Acute
| Article | Year |
|---|---|
β-hydroxybutyrate inhibits ferroptosis-mediated pancreatic damage in acute liver failure through the increase of H3K9bhb.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Animals; Ferroptosis; Hyperamylasemia; Liver Failure, Acute; M | 2022 |
Ketone Body Therapy Protects From Lipotoxicity and Acute Liver Failure Upon Pparα Deficiency.
Topics: 3-Hydroxybutyric Acid; Animals; Fatty Acids; Fatty Liver; Female; Ketone Bodies; Lipid Peroxidation; | 2015 |
A novel scoring system for prognostic prediction in d-galactosamine/lipopolysaccharide-induced fulminant hepatic failure BALB/c mice.
Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Disease Models, Animal; Galactosamine; Lipopolysaccharid | 2009 |
Plasma exchange and the arterial blood ketone body ratio in patients with acute hepatic failure.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Arteries; Child; Citrates; Citric Acid; Female; H | 1994 |