3-hydroxybutyric acid has been researched along with Liver Dysfunction in 13 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein." | 7.68 | Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992) |
| "To evaluate the effects of acute pancreatitis on the energy metabolism of the liver and on the fragility of hepatic cells and subcellular organelles, we studies (1) the arterial blood ketone body ratio (BKBR) (aceto acetate/beta-hydroxy butyrate), which is in equilibrium with the free NAD+/NADH ratio in liver mitochondria; (2) the hepatic energy charge (EC) = (ATP + 1/2 ADP)/(ATP + ADP + AMP); (3) the cathepsin B leakage from hepatic lysosomes and the malate dehydrogenase leakage from hepatic mitochondria in vitro; and (4) the protective effects of prostaglandin E2 (PGE2) and a new synthetic protease inhibitor ONO 3307 on hepatic injury in acute pancreatitis induced in rats by a supramaximal dose of caerulein." | 3.68 | Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307. ( Hirano, T; Manabe, T; Tobe, T, 1992) |
| "Liver ischemia and reperfusion injury (IRI) is a major challenge in liver surgery." | 1.51 | Up-regulation of FOXO1 and reduced inflammation by β-hydroxybutyric acid are essential diet restriction benefits against liver injury. ( Hirao, H; Kadono, K; Kawasoe, J; Miyauchi, T; Okajima, H; Terajima, H; Uchida, Y; Ueda, S; Uemoto, S; Watanabe, T, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (53.85) | 18.2507 |
| 2000's | 3 (23.08) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 1 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Li, K | 1 |
| Wang, WH | 1 |
| Wu, JB | 1 |
| Xiao, WH | 1 |
| Miyauchi, T | 1 |
| Uchida, Y | 1 |
| Kadono, K | 1 |
| Hirao, H | 1 |
| Kawasoe, J | 1 |
| Watanabe, T | 1 |
| Ueda, S | 1 |
| Okajima, H | 1 |
| Terajima, H | 1 |
| Uemoto, S | 1 |
| Li, P | 1 |
| Zhang, J | 1 |
| Liu, J | 2 |
| Ma, H | 1 |
| Lie, P | 1 |
| Wang, Y | 1 |
| Liu, G | 1 |
| Zeng, H | 1 |
| Li, Z | 1 |
| Wei, X | 1 |
| Komatsu, Y | 1 |
| Itoh, N | 1 |
| Taniyama, H | 1 |
| Kitazawa, T | 1 |
| Yokota, H | 1 |
| Koiwa, M | 1 |
| Ohtsuka, H | 1 |
| Terasaki, N | 1 |
| Maeno, K | 1 |
| Mizoguchi, M | 1 |
| Takeuchi, Y | 1 |
| Tanigawa, M | 1 |
| Nakamura, T | 1 |
| Watanabe, H | 1 |
| Matsuguchi, Y | 1 |
| Kukino, T | 1 |
| Honma, A | 1 |
| Tedesco, D | 1 |
| Tava, A | 1 |
| Galletti, S | 1 |
| Tameni, M | 1 |
| Varisco, G | 1 |
| Costa, A | 1 |
| Steidler, S | 1 |
| Nakamura, M | 1 |
| Chen, HM | 1 |
| Momoi, Y | 1 |
| Iwasaki, T | 1 |
| Nagamine, T | 1 |
| Saito, S | 1 |
| Yamada, S | 1 |
| Arai, T | 1 |
| Takehara, K | 1 |
| Fukui, T | 1 |
| Skarzyńska, E | 1 |
| Tomaszewski, P | 1 |
| Polański, JA | 1 |
| Pachecka, J | 1 |
| Higashi, S | 1 |
| Tabata, N | 1 |
| Kondo, KH | 1 |
| Kai, M | 1 |
| Miyamoto, K | 1 |
| Maeda, Y | 1 |
| Setoguchi, T | 1 |
| Tornquist, SJ | 1 |
| Van Saun, RJ | 1 |
| Smith, BB | 1 |
| Cebra, CK | 1 |
| Snyder, SP | 1 |
| Hamanoue, M | 1 |
| Aikou, T | 1 |
| Tanabe, G | 1 |
| Takao, S | 1 |
| Shimazu, H | 1 |
| Kimotsuki, K | 1 |
| Nagashige, M | 1 |
| Hirano, T | 1 |
| Manabe, T | 1 |
| Tobe, T | 1 |
| Schlichtig, R | 1 |
| Klions, HA | 1 |
| Kramer, DJ | 1 |
| Nemoto, EM | 1 |
1 review available for 3-hydroxybutyric acid and Liver Dysfunction
| Article | Year |
|---|---|
β-hydroxybutyrate: A crucial therapeutic target for diverse liver diseases.
Topics: 3-Hydroxybutyric Acid; Diet, Ketogenic; Humans; Ketone Bodies; Ketosis; Liver Diseases | 2023 |
1 trial available for 3-hydroxybutyric acid and Liver Dysfunction
| Article | Year |
|---|---|
[Ketone bodies in patients after partially liver resection].
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Biomarkers; Female; Humans; Hydroxybutyrates; Ket | 1996 |
11 other studies available for 3-hydroxybutyric acid and Liver Dysfunction
| Article | Year |
|---|---|
Up-regulation of FOXO1 and reduced inflammation by β-hydroxybutyric acid are essential diet restriction benefits against liver injury.
Topics: 3-Hydroxybutyric Acid; Animals; Fasting; Forkhead Box Protein O1; Inflammation; Liver; Liver Disease | 2019 |
Promoting the recovery of injured liver with poly (3-hydroxybutyrate-co-3-hydroxyvalerate-co-3-hydroxyhexanoate) scaffolds loaded with umbilical cord-derived mesenchymal stem cells.
Topics: 3-Hydroxybutyric Acid; Animals; Biocompatible Materials; Caproates; Cord Blood Stem Cell Transplanta | 2015 |
Classification of abomasal displacement in cows according to histopathology of the liver and clinical chemistry.
Topics: 3-Hydroxybutyric Acid; Abomasum; Animals; Aspartate Aminotransferases; Blood Chemical Analysis; Bloo | 2002 |
Effects of silymarin, a natural hepatoprotector, in periparturient dairy cows.
Topics: 3-Hydroxybutyric Acid; Animals; Body Composition; Cattle; Cattle Diseases; Colostrum; Drug Residues; | 2004 |
Clinical application of computed tomography for the diagnosis of feline hepatic lipidosis.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Chemical Analysis; Cat Diseases; Cats; Fatty Acids, Nonesterif | 2005 |
Biotinidase activity in patients with liver disease.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Adult; Aged; Amidohydrolases; Biotin; Biotinidase; Carcinoma, | 1993 |
A predominant increase of arterial beta-hydroxybutyrate concentration during partial hepatectomies in patients with impaired indocyanine green clearance test.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Coloring Agents; Female; Hepatectomy; Hepatic Veins; Humans; I | 1999 |
Hepatic lipidosis in llamas and alpacas: 31 cases (1991-1997).
Topics: 3-Hydroxybutyric Acid; Animals; Anorexia; Aspartate Aminotransferases; Bile Acids and Salts; Camelid | 1999 |
A correlation between arterial ketone body ratio and concentration of beta-hydroxybutyrate as an indicator of hepatic functional reserve.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Aged, 80 and over; Biliary Tract Diseases; Female; Glucose Toler | 1992 |
Impaired hepatic energy metabolism in rat acute pancreatitis: protective effects of prostaglandin E2 and synthetic protease inhibitor ONO 3307.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acute Disease; Adenosine Diphosphate; Adenosine Triphosphate; | 1992 |
Hepatic dysoxia commences during O2 supply dependence.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Dogs; Hemorrhage; Hydroxybutyrates; Lactates; Lactic | 1992 |