3-hydroxybutyric acid has been researched along with Lipid Metabolism, Inborn Error in 8 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Metabolic changes (liver steatosis and loss of muscle glycogen stores) appear also early after carnitine deprivation." | 3.74 | Effect of carnitine deprivation on carnitine homeostasis and energy metabolism in mice with systemic carnitine deficiency. ( Beier, K; Knapp, AC; Krähenbühl, S; Todesco, L; Torok, M, 2008) |
| "Triheptanoin is an odd-carbon, medium-chain triglyceride consisting of 3 fatty acids with 7 carbons each on a glycerol backbone developed to treat adult and pediatric patients with LC-FAODs." | 3.01 | The Pharmacokinetics of Triheptanoin and Its Metabolites in Healthy Subjects and Patients With Long-Chain Fatty Acid Oxidation Disorders. ( Gupta, M; Lee, SK; McKeever, K; Shi, J, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, SK | 1 |
| Gupta, M | 1 |
| Shi, J | 1 |
| McKeever, K | 1 |
| Semeraro, M | 1 |
| Boenzi, S | 1 |
| Carrozzo, R | 1 |
| Diodato, D | 1 |
| Martinelli, D | 1 |
| Olivieri, G | 1 |
| Antonetti, G | 1 |
| Sacchetti, E | 1 |
| Catesini, G | 1 |
| Rizzo, C | 1 |
| Dionisi-Vici, C | 1 |
| Knapp, AC | 1 |
| Todesco, L | 1 |
| Torok, M | 1 |
| Beier, K | 1 |
| Krähenbühl, S | 1 |
| Treacy, E | 1 |
| Pitt, J | 1 |
| Eggington, M | 1 |
| Hawkins, R | 1 |
| Wanders, RJ | 1 |
| Ijlst, L | 1 |
| Bonnefont, JP | 1 |
| Specola, NB | 1 |
| Vassault, A | 1 |
| Lombes, A | 1 |
| Ogier, H | 1 |
| de Klerk, JB | 1 |
| Munnich, A | 1 |
| Coude, M | 1 |
| Paturneau-Jouas, M | 1 |
| Saudubray, JM | 1 |
| Treem, WR | 1 |
| Stanley, CA | 1 |
| Goodman, SI | 1 |
| Amendt, BA | 1 |
| Greene, C | 1 |
| Sweetman, L | 1 |
| Cloherty, J | 1 |
| Shih, V | 1 |
| Moon, A | 1 |
| Teel, L | 1 |
| Rhead, WJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fasting Tolerance in Patients With Medium-chain Acyl-CoA Dehydrogenase Deficiency (MCADD) in the First Six Months of Life: an Investigator-initiated Human Pilot-study[NCT03761693] | 20 participants (Anticipated) | Interventional | 2019-05-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for 3-hydroxybutyric acid and Lipid Metabolism, Inborn Error
| Article | Year |
|---|---|
The Pharmacokinetics of Triheptanoin and Its Metabolites in Healthy Subjects and Patients With Long-Chain Fatty Acid Oxidation Disorders.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Child; Cross-Over Studies; Fatty Acids; Female; Healthy Vo | 2021 |
7 other studies available for 3-hydroxybutyric acid and Lipid Metabolism, Inborn Error
| Article | Year |
|---|---|
The urinary organic acids profile in single large-scale mitochondrial DNA deletion disorders.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase, Long-Chain; Adolescent; Child; Child, Preschool; Cong | 2018 |
Effect of carnitine deprivation on carnitine homeostasis and energy metabolism in mice with systemic carnitine deficiency.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Body Weight; Carnitine; Energy Metabolism; F | 2008 |
Dicarboxylic aciduria, significance and prognostic indications.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase; Adipates; Child; Child, Preschool; Diagnosis, Differe | 1994 |
Fatty acid beta-oxidation in leukocytes from control subjects and medium-chain acyl-CoA dehydrogenase deficient patients.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase; Acyl-CoA Dehydrogenases; Caprylates; Fatty Acids; Hum | 1992 |
The fasting test in paediatrics: application to the diagnosis of pathological hypo- and hyperketotic states.
Topics: 3-Hydroxybutyric Acid; Adolescent; Blood Glucose; Child; Child, Preschool; Fasting; Fatty Acids, Non | 1990 |
Medium-chain acyl-CoA dehydrogenase deficiency: metabolic effects and therapeutic efficacy of long-term L-carnitine supplementation.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenases; Carnitine; Chromatography, Gas; Fasting; Fatty Acids | 1989 |
Short-chain acyl-coenzyme A dehydrogenase deficiency. Clinical and biochemical studies in two patients.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenases; Adipates; Adult; Butyrates; Butyric Acid; Female; Fi | 1987 |