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3-hydroxybutyric acid and Ischemia

3-hydroxybutyric acid has been researched along with Ischemia in 10 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
" These issues are being addressed by designing and synthesizing orally bioavailable multimers of betaOHB with improved pharmacokinetics."2.43KTX 0101: a potential metabolic approach to cytoprotection in major surgery and neurological disorders. ( Heal, DJ; Martin, KF; Smith, SL, 2005)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's3 (30.00)18.2507
2000's1 (10.00)29.6817
2010's1 (10.00)24.3611
2020's2 (20.00)2.80

Authors

AuthorsStudies
Lindsay, RT1
Dieckmann, S1
Krzyzanska, D1
Manetta-Jones, D1
West, JA1
Castro, C1
Griffin, JL1
Murray, AJ1
Lehto, A1
Koch, K1
Barnstorf-Brandes, J1
Viel, C1
Fuchs, M1
Klein, J1
Tran, MT1
Zsengeller, ZK1
Berg, AH1
Khankin, EV1
Bhasin, MK1
Kim, W1
Clish, CB1
Stillman, IE1
Karumanchi, SA1
Rhee, EP1
Parikh, SM1
Smith, SL1
Heal, DJ1
Martin, KF1
Cunarro, JA1
Schultz, SE1
Johnson, WA1
Weiner, MW1
Yamamoto, M1
Ozawa, K2
Isselhard, W1
Tobe, T1
Lestan, B1
Walden, K1
Schmaltz, S1
Spychala, J1
Fox, IH1
Willis, N1
Mogridge, J1
Yamaguchi, M1
Higashiyama, H1
Kumada, K1
Okamoto, R1
Ueda, J1
Shimahara, Y1
Hörl, M1
Hörl, WH1

Reviews

1 review available for 3-hydroxybutyric acid and Ischemia

ArticleYear
KTX 0101: a potential metabolic approach to cytoprotection in major surgery and neurological disorders.
    CNS drug reviews, 2005,Summer, Volume: 11, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Brain Infarction; Cell Death; Disease Models

2005

Trials

1 trial available for 3-hydroxybutyric acid and Ischemia

ArticleYear
beta-Hydroxybutyrate decreases adenosine triphosphate degradation products in human subjects.
    The Journal of laboratory and clinical medicine, 1994, Volume: 124, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Adolescent; Adult; Ammonia; Exercise; Fructose; Human

1994

Other Studies

8 other studies available for 3-hydroxybutyric acid and Ischemia

ArticleYear
β-hydroxybutyrate accumulates in the rat heart during low-flow ischaemia with implications for functional recovery.
    eLife, 2021, 09-07, Volume: 10

    Topics: 3-Hydroxybutyric Acid; Animals; Chromatography, Liquid; Citric Acid Cycle; Heart; Hydroxymethylgluta

2021
ß-Hydroxybutyrate Improves Mitochondrial Function After Transient Ischemia in the Mouse.
    Neurochemical research, 2022, Volume: 47, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Citrates; Hydroxybutyrates; Ischemia; Ketone Bodies; Mice; Mitochond

2022
PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
    Nature, 2016, Mar-24, Volume: 531, Issue:7595

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Adipose Tissue; Amino Acids; Animals; Cytokines; Dinopro

2016
Effects of ischemia on metabolite concentrations in dog renal cortex.
    Renal physiology, 1982, Volume: 5, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Trip

1982
Acetoacetate/beta-hydroxybutyrate ratio in arterial blood and liver during and after liver ischemia--a clue to detect the viability of ischemic liver.
    Nihon geka hokan. Archiv fur japanische Chirurgie, 1983, Jul-01, Volume: 52, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Hydroxybutyrates; Ischemia; Liver; Male; Rats; Rats,

1983
Indicators of histohypoxia.
    Acta anaesthesiologica Scandinavica. Supplementum, 1995, Volume: 107

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Carbon Dioxide; Cardiac Output; Cell Hypoxia; Cell Survival; C

1995
Evaluation of temporary portal vein arterialization: the minimum arterialized blood flow for maintaining liver viability.
    Transplant international : official journal of the European Society for Organ Transplantation, 1990, Volume: 3, Issue:3

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Flow Velocity; Butyrates; Dogs; Energy Metaboli

1990
Effect of tourniquet ischaemia on carbohydrate metabolism of dog skeletal muscle.
    European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes, 1985, Volume: 17, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Citrates; Citric Acid; Dogs; Energy Metabolism; Femal

1985