3-hydroxybutyric acid has been researched along with Inborn Errors of Metabolism in 9 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "L-carnitine treatment prevented this fall in plasma carnitine and resulted in greater increases in excretion of acylcarnitines." | 2.71 | L-carnitine and exercise tolerance in medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency: a pilot study. ( Chalmers, RA; Harrison, EL; Jones, MG; Jones, S; Lee, PJ; Leonard, JV, 2005) |
| "Normally, the presence of ketosis implies 2 things: that lipid energy metabolism has been activated and that the entire pathway of lipid degradation is intact." | 2.39 | Medical aspects of ketone body metabolism. ( Ashmarina, L; Boukaftane, Y; Kassovska-Bratinova, S; Lambert, M; Lapierre, P; Mitchell, GA; Potier, E; Robert, MF; Wang, SP, 1995) |
| "Patients with hereditary fructose intolerance, a rare inborn error of metabolism caused by a defect in aldolase B (n = 15), and healthy persons matched for age, sex, and body mass index (BMI) (n =15)." | 1.51 | Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content. ( Bons, JAP; Brouwers, MCGJ; Cassiman, D; Debray, FG; Feskens, EJM; Hodson, L; Hollak, CEM; Koek, GH; Kooi, ME; Lefeber, DJ; Lindeboom, L; Schalkwijk, CG; Schaper, NC; Simons, N; Stehouwer, CDA, 2019) |
| "Creatine excretion was measured in two patients with methylmalonic aciduria and two patients with 3-hydroxy-3-methylglutaric aciduria." | 1.28 | Creatine metabolism during metabolic perturbations in patients with organic acidurias. ( Chalmers, RA; Davies, SE; Iles, RA; Stacey, TE, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Simons, N | 1 |
| Debray, FG | 1 |
| Schaper, NC | 1 |
| Kooi, ME | 1 |
| Feskens, EJM | 1 |
| Hollak, CEM | 1 |
| Lindeboom, L | 1 |
| Koek, GH | 1 |
| Bons, JAP | 1 |
| Lefeber, DJ | 1 |
| Hodson, L | 1 |
| Schalkwijk, CG | 1 |
| Stehouwer, CDA | 1 |
| Cassiman, D | 1 |
| Brouwers, MCGJ | 1 |
| Carragher, FM | 1 |
| Bonham, JR | 1 |
| Smith, JM | 1 |
| Lee, PJ | 1 |
| Harrison, EL | 1 |
| Jones, MG | 1 |
| Jones, S | 1 |
| Leonard, JV | 1 |
| Chalmers, RA | 2 |
| Mitchell, GA | 1 |
| Kassovska-Bratinova, S | 1 |
| Boukaftane, Y | 1 |
| Robert, MF | 1 |
| Wang, SP | 1 |
| Ashmarina, L | 1 |
| Lambert, M | 1 |
| Lapierre, P | 1 |
| Potier, E | 1 |
| Marsden, D | 1 |
| Barshop, BA | 1 |
| Capistrano-Estrada, S | 1 |
| Rice, M | 1 |
| Prodanos, C | 1 |
| Sartoris, D | 1 |
| Wolff, J | 1 |
| Jones, KL | 1 |
| Spector, S | 1 |
| Nyhan, WL | 1 |
| Fukao, T | 1 |
| Song, XQ | 1 |
| Watanabe, H | 1 |
| Hirayama, K | 1 |
| Sakazaki, H | 1 |
| Shintaku, H | 1 |
| Imanaka, M | 1 |
| Orii, T | 1 |
| Kondo, N | 1 |
| Fletcher, JM | 1 |
| Pitt, JJ | 1 |
| Davies, SE | 1 |
| Iles, RA | 1 |
| Stacey, TE | 1 |
| Peterson, C | 1 |
| Goldman, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fasting Tolerance in Patients With Medium-chain Acyl-CoA Dehydrogenase Deficiency (MCADD) in the First Six Months of Life: an Investigator-initiated Human Pilot-study[NCT03761693] | 20 participants (Anticipated) | Interventional | 2019-05-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 3-hydroxybutyric acid and Inborn Errors of Metabolism
| Article | Year |
|---|---|
Medical aspects of ketone body metabolism.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Biological Evolution; Brain; Humans; Hydroxybutyrates | 1995 |
2 trials available for 3-hydroxybutyric acid and Inborn Errors of Metabolism
| Article | Year |
|---|---|
L-carnitine and exercise tolerance in medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency: a pilot study.
Topics: 3-Hydroxybutyric Acid; Acids; Acyl-CoA Dehydrogenase; Adolescent; Adult; Anaerobic Threshold; Blood | 2005 |
Fasting medium chain acyl-coenzyme A dehydrogenase--deficient children can make ketones.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acyl-CoA Dehydrogenase; Age of Onset; Carbon Isotopes; Child; | 2001 |
6 other studies available for 3-hydroxybutyric acid and Inborn Errors of Metabolism
| Article | Year |
|---|---|
Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Body Composition; Body Mass Index; Case-Control Studies | 2019 |
Pitfalls in the measurement of some intermediary metabolites.
Topics: 3-Hydroxybutyric Acid; Artifacts; Biomarkers; Diagnostic Techniques and Procedures; Fatty Acids, Non | 2003 |
Anabolic effect of human growth hormone: management of inherited disorders of catabolic pathways.
Topics: 3-Hydroxybutyric Acid; Adolescent; Age Determination by Skeleton; Bone Density; Child; Dietary Prote | 1994 |
Prenatal diagnosis of succinyl-coenzyme A:3-ketoacid coenzyme A transferase deficiency.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetyl-CoA C-Acetyltransferase; Amniocentesis; Amniotic Fluid; | 1996 |
Creatine metabolism during metabolic perturbations in patients with organic acidurias.
Topics: 3-Hydroxybutyric Acid; Carnitine; Child; Child, Preschool; Creatine; Creatinine; Female; Humans; Hyd | 1990 |
In vitro acetylcholine synthesis and oxidative metabolism during development of normal and brindled mouse brain.
Topics: 3-Hydroxybutyric Acid; Acetylcholine; Age Factors; Animals; Brain; Choline O-Acetyltransferase; Copp | 1986 |