Page last updated: 2024-10-17

3-hydroxybutyric acid and Hyperphagia

3-hydroxybutyric acid has been researched along with Hyperphagia in 3 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Hyperphagia: Ingestion of a greater than optimal quantity of food.

Research Excerpts

ExcerptRelevanceReference
"Dapagliflozin is a potent and selective sodium glucose cotransporter-2 (SGLT2) inhibitor which promotes urinary glucose excretion and induces weight loss."7.78Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats. ( Cullen, MJ; Devenny, JJ; Godonis, HE; Harvey, SJ; Pelleymounter, MA; Rooney, S, 2012)
"Dapagliflozin is a potent and selective sodium glucose cotransporter-2 (SGLT2) inhibitor which promotes urinary glucose excretion and induces weight loss."3.78Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats. ( Cullen, MJ; Devenny, JJ; Godonis, HE; Harvey, SJ; Pelleymounter, MA; Rooney, S, 2012)
" These data indicate that many patients with bulimia showed the metabolic signs of starvation at the time of the study, a finding supported by the symptoms of endocrine adaptation to starvation, namely low triiodothyronine and a decreased noradrenaline response to an orthostatic test in many of these patients."3.67Metabolic and endocrine indices of starvation in bulimia: a comparison with anorexia nervosa. ( Pahl, J; Pirke, KM; Schweiger, U; Warnhoff, M, 1985)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Devenny, JJ1
Godonis, HE1
Harvey, SJ1
Rooney, S1
Cullen, MJ1
Pelleymounter, MA1
Laessle, RG1
Platte, P1
Schweiger, U2
Pirke, KM2
Pahl, J1
Warnhoff, M1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of the Treatment With Dapagliflozin and Metformin Compared to Metformin Monotherapy for Weight Loss on Diabetic and Prediabetic Patients With Obesity Class III[NCT03968224]Phase 2/Phase 390 participants (Anticipated)Interventional2018-07-07Recruiting
Combined Effects of SGLT2 Inhibition and GLP-1 Receptor Agonism on Food Intake, Body Weight and Central Satiety and Reward Circuits in Obese T2DM Patients[NCT03361098]Phase 465 participants (Actual)Interventional2017-09-18Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for 3-hydroxybutyric acid and Hyperphagia

ArticleYear
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Obesity Agents; Benzhydryl Compounds; Blood Glucose; Caloric Re

2012
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Obesity Agents; Benzhydryl Compounds; Blood Glucose; Caloric Re

2012
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Obesity Agents; Benzhydryl Compounds; Blood Glucose; Caloric Re

2012
Weight loss induced by chronic dapagliflozin treatment is attenuated by compensatory hyperphagia in diet-induced obese (DIO) rats.
    Obesity (Silver Spring, Md.), 2012, Volume: 20, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Obesity Agents; Benzhydryl Compounds; Blood Glucose; Caloric Re

2012
Biological and psychological correlates of intermittent dieting behavior in young women. A model for bulimia nervosa.
    Physiology & behavior, 1996, Volume: 60, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Affect; Body Weight; Bulimia; Diet, Reducing; Energy Intak

1996
Metabolic and endocrine indices of starvation in bulimia: a comparison with anorexia nervosa.
    Psychiatry research, 1985, Volume: 15, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Anorexia Nervosa; Fatty Acids, Nonesterified; Feeding and

1985