3-hydroxybutyric acid has been researched along with Hepatocellular Carcinoma in 13 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the second set of experiments, hypertrophy of the adipocytes was suppressed, and the concentration of adiponectin and leptin in the adipose tissue decreased by MCT." | 3.91 | Effects of Medium-chain Triglycerides Administration in Chemically-induced Carcinogenesis in Mice. ( Akazawa, Y; Fujii, H; Fukushima, H; Hagio, K; Ichikawa, D; Kono, H; Maruyama, S; Nakata, Y; Wakana, H, 2019) |
| "In contrast, the behaviors of C3A/HepG2 hepatoma cells presented an opposite outcomes." | 1.35 | Modulating the activities of human mesenchymal stem cells (hMSCs) and C3A/HepG2 hepatoma cells by modifying the surface characteristics of poly(3-hydroxybutyrate-co-3-hydroxyhexnoate) (PHBHHx). ( Hu, SW; Lee, YT; Sun, YM; Young, TH; Yu, BY, 2009) |
| "These data indicated that AS-30D hepatoma cells had a predominantly oxidative and not a glycolytic type of metabolism." | 1.31 | Substrate oxidation and ATP supply in AS-30D hepatoma cells. ( Moreno-Sánchez, R; Rodríguez-Enríquez, S; Torres-Márquez, ME, 2000) |
| "Morris hepatoma 7777 cells freshly isolated from highly malignant tumors grown in the hindlimb of buffalo rats actively convert ketone bodies to cholesterol and fatty acids." | 1.29 | Utilization and preferred metabolic pathway of ketone bodies for lipid synthesis by isolated rat hepatoma cells. ( Elson, C; Hildebrandt, LA; Shrago, E; Spennetta, T, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 5 (38.46) | 2.80 |
| Authors | Studies |
|---|---|
| Cui, X | 2 |
| Yun, X | 2 |
| Sun, M | 2 |
| Li, R | 2 |
| Lyu, X | 2 |
| Lao, Y | 2 |
| Qin, X | 2 |
| Yu, W | 2 |
| Suk, FM | 1 |
| Wu, CY | 1 |
| Fang, CC | 1 |
| Chen, TL | 1 |
| Liao, YJ | 1 |
| Mikami, D | 1 |
| Kobayashi, M | 1 |
| Uwada, J | 1 |
| Yazawa, T | 1 |
| Kamiyama, K | 1 |
| Nishimori, K | 1 |
| Nishikawa, Y | 1 |
| Nishikawa, S | 1 |
| Yokoi, S | 1 |
| Taniguchi, T | 1 |
| Iwano, M | 1 |
| Wakana, H | 1 |
| Kono, H | 1 |
| Fukushima, H | 1 |
| Nakata, Y | 1 |
| Akazawa, Y | 1 |
| Maruyama, S | 1 |
| Hagio, K | 1 |
| Fujii, H | 1 |
| Ichikawa, D | 1 |
| Zhang, H | 1 |
| Chang, Z | 1 |
| Qin, LN | 1 |
| Liang, B | 1 |
| Han, JX | 1 |
| Qiao, KL | 1 |
| Yang, C | 1 |
| Liu, YR | 1 |
| Zhou, HG | 1 |
| Sun, T | 1 |
| Feng, Z | 1 |
| Nadikudi, M | 1 |
| Woolley, KL | 1 |
| Hemasa, AL | 1 |
| Chear, S | 1 |
| Smith, JA | 1 |
| Gueven, N | 1 |
| Yu, BY | 1 |
| Hu, SW | 1 |
| Sun, YM | 1 |
| Lee, YT | 1 |
| Young, TH | 1 |
| Tani, T | 2 |
| Taki, Y | 2 |
| Aoyama, H | 1 |
| Jikkoh, A | 1 |
| Arii, S | 1 |
| Ozawa, K | 3 |
| Tobe, T | 2 |
| Hildebrandt, LA | 1 |
| Spennetta, T | 1 |
| Elson, C | 1 |
| Shrago, E | 1 |
| Nagamine, T | 1 |
| Saito, S | 1 |
| Yamada, S | 1 |
| Arai, T | 1 |
| Takehara, K | 1 |
| Fukui, T | 1 |
| Kajimura, K | 1 |
| Moriyasu, F | 1 |
| Someda, H | 1 |
| Okuma, M | 1 |
| Mori, K | 1 |
| Rodríguez-Enríquez, S | 1 |
| Torres-Márquez, ME | 1 |
| Moreno-Sánchez, R | 1 |
| Jikko, A | 1 |
| Minematsu, S | 1 |
| Yamamoto, M | 1 |
| Kamiyama, Y | 1 |
13 other studies available for 3-hydroxybutyric acid and Hepatocellular Carcinoma
| Article | Year |
|---|---|
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
Topics: 3-Hydroxybutyric Acid; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dipeptidyl Peptidase 4; | 2023 |
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
Topics: 3-Hydroxybutyric Acid; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dipeptidyl Peptidase 4; | 2023 |
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
Topics: 3-Hydroxybutyric Acid; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dipeptidyl Peptidase 4; | 2023 |
HMGCL-induced β-hydroxybutyrate production attenuates hepatocellular carcinoma via DPP4-mediated ferroptosis susceptibility.
Topics: 3-Hydroxybutyric Acid; Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Dipeptidyl Peptidase 4; | 2023 |
β-HB treatment reverses sorafenib resistance by shifting glycolysis-lactate metabolism in HCC.
Topics: 3-Hydroxybutyric Acid; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Drug Resi | 2023 |
β-Hydroxybutyrate enhances the cytotoxic effect of cisplatin via the inhibition of HDAC/survivin axis in human hepatocellular carcinoma cells.
Topics: 3-Hydroxybutyric Acid; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Cell Li | 2020 |
Effects of Medium-chain Triglycerides Administration in Chemically-induced Carcinogenesis in Mice.
Topics: 3-Hydroxybutyric Acid; Adipocytes; Adipokines; Adiponectin; Adipose Tissue; Aldehydes; Animal Feed; | 2019 |
MTA2 triggered R-loop trans-regulates BDH1-mediated β-hydroxybutyrylation and potentiates propagation of hepatocellular carcinoma stem cells.
Topics: 3-Hydroxybutyric Acid; Carcinoma, Hepatocellular; Histone Deacetylases; Humans; Liver Neoplasms; Neo | 2021 |
Bioactivity Profiles of Cytoprotective Short-Chain Quinones.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Apoptosis; Carcinoma, Hepatocellular; Cell Proliferat | 2021 |
Modulating the activities of human mesenchymal stem cells (hMSCs) and C3A/HepG2 hepatoma cells by modifying the surface characteristics of poly(3-hydroxybutyrate-co-3-hydroxyhexnoate) (PHBHHx).
Topics: 3-Hydroxybutyric Acid; Adult; Biocompatible Materials; Bone Marrow Cells; Caproates; Carbon Dioxide; | 2009 |
Changes in acetoacetate/beta-hydroxybutyrate ratio in arterial blood following hepatic artery embolization in man.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Carcinoma, Hepatocellular; Embolization, Therapeu | 1984 |
Utilization and preferred metabolic pathway of ketone bodies for lipid synthesis by isolated rat hepatoma cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Carcinoma, Hepatocellular; Cell Separation; Citrates; | 1995 |
Biotinidase activity in patients with liver disease.
Topics: 3-Hydroxybutyric Acid; Acute Disease; Adult; Aged; Amidohydrolases; Biotin; Biotinidase; Carcinoma, | 1993 |
Transcatheter hepatic arterial drug infusion therapy for hepatocellular carcinoma. Effect on the arterial ketone body ratio.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aged; Antineoplastic Agents; Butyrates; Carcinoma, Hepatocellu | 1993 |
Substrate oxidation and ATP supply in AS-30D hepatoma cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Carcinoma, Hepatocellular; Ce | 2000 |
Short-term changes in blood ketone body ratios in the phase immediately after hepatic artery embolization: their clinical significance.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Carcinoma, Hepatocellular; Embolization, Therapeu | 1986 |