3-hydroxybutyric acid has been researched along with Hemorrhagic Shock in 12 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "d-β-hydroxybutyrate and melatonin (BHB/MLT) infusion improves survival in hemorrhagic shock models." | 7.88 | Evaluation of novel formulations of d-β-hydroxybutyrate and melatonin in a rat model of hemorrhagic shock. ( Beilman, GJ; Mulier, KE; Suryanarayanan, R; Thakral, S; Wolf, A, 2018) |
| "Treatment with a combination of D-β-hydroxybutyrate (BHB) and melatonin (M) improves survival in hemorrhagic shock models." | 7.85 | D-β-Hydroxybutyrate and melatonin for treatment of porcine hemorrhagic shock and injury: a melatonin dose-ranging study. ( Beilman, GJ; Mulier, KE; Muratore, SL; Wolf, A, 2017) |
| "D-ß-hydroxybutyrate (BHB) and melatonin (M) treatment improves survival in animal models of hemorrhagic shock." | 7.81 | Safety of D-ß-Hydroxybutyrate and Melatonin for the Treatment of Hemorrhagic Shock With Polytrauma. ( Asghar, JI; Beilman, GJ; Iyegha, UP; Mulier, KE; Wolf, A, 2015) |
| "A patient with acute copper sulfate poisoning was found to have maintained a relatively oxidized hepatic mitochondrial redox state in spite of his being in refractory shock." | 7.69 | Redox state in liver mitochondria in acute copper sulfate poisoning. ( Kobayashi, K; Nakatani, T; Spolter, L, 1994) |
| "Previous studies in rat models of hemorrhagic shock have suggested a benefit." | 5.38 | Treatment with beta-hydroxybutyrate and melatonin is associated with improved survival in a porcine model of hemorrhagic shock. ( Beilman, GJ; Greenberg, JJ; Lexcen, DR; Luzcek, E; Mulier, KE, 2012) |
| "Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation." | 5.30 | Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998) |
| "d-β-hydroxybutyrate and melatonin (BHB/MLT) infusion improves survival in hemorrhagic shock models." | 3.88 | Evaluation of novel formulations of d-β-hydroxybutyrate and melatonin in a rat model of hemorrhagic shock. ( Beilman, GJ; Mulier, KE; Suryanarayanan, R; Thakral, S; Wolf, A, 2018) |
| "Treatment with a combination of D-β-hydroxybutyrate (BHB) and melatonin (M) improves survival in hemorrhagic shock models." | 3.85 | D-β-Hydroxybutyrate and melatonin for treatment of porcine hemorrhagic shock and injury: a melatonin dose-ranging study. ( Beilman, GJ; Mulier, KE; Muratore, SL; Wolf, A, 2017) |
| "D-ß-hydroxybutyrate (BHB) and melatonin (M) treatment improves survival in animal models of hemorrhagic shock." | 3.81 | Safety of D-ß-Hydroxybutyrate and Melatonin for the Treatment of Hemorrhagic Shock With Polytrauma. ( Asghar, JI; Beilman, GJ; Iyegha, UP; Mulier, KE; Wolf, A, 2015) |
| "A small-volume therapeutic approach based on the biochemistry of hibernating mammals was evaluated to test the hypothesis that passive hypothermia and systemic administration of d-β-hydroxybutyrate (d-BHB) plus melatonin will increase survival of animals subjected to hemorrhagic shock ([HS] 60% blood loss)." | 3.76 | Small-volume d-β-hydroxybutyrate solution infusion increases survivability of lethal hemorrhagic shock in rats. ( Andrews, MT; Drewes, LR; Klein, AH; Wendroth, SM, 2010) |
| "A patient with acute copper sulfate poisoning was found to have maintained a relatively oxidized hepatic mitochondrial redox state in spite of his being in refractory shock." | 3.69 | Redox state in liver mitochondria in acute copper sulfate poisoning. ( Kobayashi, K; Nakatani, T; Spolter, L, 1994) |
| "Previous studies in rat models of hemorrhagic shock have suggested a benefit." | 1.38 | Treatment with beta-hydroxybutyrate and melatonin is associated with improved survival in a porcine model of hemorrhagic shock. ( Beilman, GJ; Greenberg, JJ; Lexcen, DR; Luzcek, E; Mulier, KE, 2012) |
| "Pentoxifylline promotes gut ketogenesis following trauma-hemorrhage and resuscitation." | 1.30 | Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock. ( Chaudry, IH; Wang, P; Wang, W, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 2 (16.67) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Perez de Lara Rodriguez, CE | 1 |
| Drewes, LR | 2 |
| Andrews, MT | 2 |
| Wolf, A | 4 |
| Mulier, KE | 4 |
| Muratore, SL | 1 |
| Beilman, GJ | 5 |
| Thakral, S | 2 |
| Suryanarayanan, R | 2 |
| Iyegha, UP | 1 |
| Asghar, JI | 1 |
| Klein, AH | 1 |
| Wendroth, SM | 1 |
| Lexcen, DR | 1 |
| Luzcek, E | 1 |
| Greenberg, JJ | 1 |
| Koustova, E | 2 |
| Rhee, P | 2 |
| Hancock, T | 1 |
| Chen, H | 1 |
| Inocencio, R | 1 |
| Jaskille, A | 1 |
| Hanes, W | 1 |
| Valeri, CR | 1 |
| Alam, HB | 2 |
| Nakatani, T | 1 |
| Spolter, L | 1 |
| Kobayashi, K | 1 |
| Wang, W | 1 |
| Wang, P | 1 |
| Chaudry, IH | 1 |
| Austin, B | 1 |
| Hiraide, A | 1 |
| Katayama, M | 1 |
| Mizobata, Y | 1 |
| Sugimoto, H | 1 |
| Yoshioka, T | 1 |
| Sugimoto, T | 1 |
12 other studies available for 3-hydroxybutyric acid and Hemorrhagic Shock
| Article | Year |
|---|---|
Hibernation-based blood loss therapy increases survivability of lethal hemorrhagic shock in rats.
Topics: 3-Hydroxybutyric Acid; Animals; Dimethyl Sulfoxide; Fluid Therapy; Hibernation; Male; Melatonin; Rat | 2017 |
D-β-Hydroxybutyrate and melatonin for treatment of porcine hemorrhagic shock and injury: a melatonin dose-ranging study.
Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Dr | 2017 |
Development and in vivo evaluation of a novel lyophilized formulation for the treatment of hemorrhagic shock.
Topics: 3-Hydroxybutyric Acid; Animals; Chemistry, Pharmaceutical; Dimethyl Sulfoxide; Disease Models, Anima | 2018 |
Evaluation of novel formulations of d-β-hydroxybutyrate and melatonin in a rat model of hemorrhagic shock.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; 3-Hydroxybutyric Acid; Animals; Dimethyl Sulfoxide; Disease Model | 2018 |
Safety of D-ß-Hydroxybutyrate and Melatonin for the Treatment of Hemorrhagic Shock With Polytrauma.
Topics: 3-Hydroxybutyric Acid; Alanine Transaminase; Animals; Arterial Pressure; Aspartate Aminotransferases | 2015 |
Small-volume d-β-hydroxybutyrate solution infusion increases survivability of lethal hemorrhagic shock in rats.
Topics: 3-Hydroxybutyric Acid; Animals; Fluid Therapy; Male; Melatonin; Rats; Rats, Sprague-Dawley; Shock, H | 2010 |
Treatment with beta-hydroxybutyrate and melatonin is associated with improved survival in a porcine model of hemorrhagic shock.
Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Disease Models, Animal; Drug Therapy, Combination; Mal | 2012 |
Ketone and pyruvate Ringer's solutions decrease pulmonary apoptosis in a rat model of severe hemorrhagic shock and resuscitation.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Apoptosis; Energy Metabolism; Isotonic Solut | 2003 |
Redox state in liver mitochondria in acute copper sulfate poisoning.
Topics: 3-Hydroxybutyric Acid; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Copper; Copper Sulf | 1994 |
Pentoxifylline increases gut ketogenesis following trauma and hemorrhagic shock.
Topics: 3-Hydroxybutyric Acid; Acyl-CoA Dehydrogenase; Animal Feed; Animals; Disease Models, Animal; Fatty A | 1998 |
Resuscitation-induced pulmonary apoptosis and intracellular adhesion molecule-1 expression in rats are attenuated by the use of Ketone Ringer's solution.
Topics: 3-Hydroxybutyric Acid; Animals; Apoptosis; Blotting, Western; Immunohistochemistry; Intercellular Ad | 2001 |
Effect of sodium D-3-hydroxybutyrate on amino acidemia in hemorrhagic hypotension.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Hydroxybutyrates; Hypotension; Male; Rats; Rats, Inbred | 1991 |