Page last updated: 2024-10-17

3-hydroxybutyric acid and Glycosuria

3-hydroxybutyric acid has been researched along with Glycosuria in 12 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Glycosuria: The appearance of an abnormally large amount of GLUCOSE in the urine, such as more than 500 mg/day in adults. It can be due to HYPERGLYCEMIA or genetic defects in renal reabsorption (RENAL GLYCOSURIA).

Research Excerpts

ExcerptRelevanceReference
" Routine blood examinations, fructosamine, beta-hydroxybutyrate (BHB), nonesterified fatty acids (NEFA), glucagon, adiponectin, and leptin were measured before and after treatment, also water intake, and urinary electrolytes, glucose, and volume."3.88Effects of the sodium-glucose cotransporter 2 (SGLT2) inhibitor velagliflozin, a new drug with therapeutic potential to treat diabetes in cats. ( Clark, M; Hoenig, M; Reiche, D; Schaeffer, DJ, 2018)
"Youth with type 1 diabetes (T1D) infrequently achieve HbA1c targets."2.84Effects of dapagliflozin on insulin-requirement, glucose excretion and ß-hydroxybutyrate levels are not related to baseline HbA1c in youth with type 1 diabetes. ( Aschemeier, B; Biester, T; Danne, T; Fath, M; Frey, M; Kordonouri, O; Scheerer, MF, 2017)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's6 (50.00)18.2507
2000's1 (8.33)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Biester, T1
Aschemeier, B1
Fath, M1
Frey, M1
Scheerer, MF1
Kordonouri, O1
Danne, T1
Hoenig, M1
Clark, M1
Schaeffer, DJ1
Reiche, D1
Ferrannini, E1
Baldi, S1
Frascerra, S1
Astiarraga, B1
Heise, T1
Bizzotto, R1
Mari, A1
Pieber, TR1
Muscelli, E1
Hayashi, T1
Ago, K1
Ago, M1
Ogata, M1
Meier, S1
Gore, PJ1
Barnett, CM1
Cursons, RT1
Phipps, DE1
Watkins, KA1
Verkerk, GA1
Amaral-Phillips, DM1
McGilliard, AD1
Lindberg, GL1
Veenhuizen, JJ1
Young, JW1
Jiffri, E1
Broom, J1
Whiting, PH1
Birkhahn, RH1
McCombs, C1
Clemens, R1
Hubbs, J1
Overton, TR1
Drackley, JK1
Ottemann-Abbamonte, CJ1
Beaulieu, AD1
Clark, JH1
Ferré, P1
Pénicaud, L1
Hitier, Y1
Meier, M1
Girard, J1
Briffeuil, P1
Huynh Thu, T1
Kolanowski, J1
Smalley, DL1
Bradley, ME1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of SGLT-2 Inhibitor on Myocardial Perfusion, Function and Metabolism in Type 2 DM Patients at High Cardiovascular Risk: The SIMPle Randomized Clinical Trial[NCT03151343]Phase 392 participants (Actual)Interventional2017-03-29Completed
Sodium-Glucose Cotransporter-2 Inhibitors: A Potential Novel Treatment for Epilepsy[NCT05512130]Early Phase 118 participants (Anticipated)Interventional2022-08-17Recruiting
Effect of Dapagliflozin on Metabolomics and Cardiac Mechanics in Chronic Kidney Disease[NCT05719714]Phase 1/Phase 260 participants (Anticipated)Interventional2023-11-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for 3-hydroxybutyric acid and Glycosuria

ArticleYear
Effects of dapagliflozin on insulin-requirement, glucose excretion and ß-hydroxybutyrate levels are not related to baseline HbA1c in youth with type 1 diabetes.
    Diabetes, obesity & metabolism, 2017, Volume: 19, Issue:11

    Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Benzhydryl Compounds; Child; Cross-Over Studies; Diabetes

2017
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016
Shift to Fatty Substrate Utilization in Response to Sodium-Glucose Cotransporter 2 Inhibition in Subjects Without Diabetes and Patients With Type 2 Diabetes.
    Diabetes, 2016, Volume: 65, Issue:5

    Topics: 3-Hydroxybutyric Acid; Algorithms; Benzhydryl Compounds; C-Reactive Protein; Carbohydrate Metabolism

2016

Other Studies

10 other studies available for 3-hydroxybutyric acid and Glycosuria

ArticleYear
Effects of the sodium-glucose cotransporter 2 (SGLT2) inhibitor velagliflozin, a new drug with therapeutic potential to treat diabetes in cats.
    Journal of veterinary pharmacology and therapeutics, 2018, Volume: 41, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adiponectin; Animals; Cat Diseases; Cats; Diabetes Mellitus; Drinking; Electr

2018
Positional asphyxia or diabetic ketoacidosis? A case report.
    Legal medicine (Tokyo, Japan), 2011, Volume: 13, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetone; Aged; Asphyxia; Diabetic Ketoacidosis; Diabetic Nephropathies; Femal

2011
Metabolic adaptations associated with irreversible glucose loss are different to those observed during under-nutrition.
    Domestic animal endocrinology, 2008, Volume: 34, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adaptation, Physiological; Animals; Cattle; Cattle Diseases; Fatty Acids, Non

2008
Effects of decreased availability of glucose for dairy cows.
    Journal of dairy science, 1993, Volume: 76, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Diet; Energy Metabolism; Fatty Acids, Nonesterified; Female;

1993
Altered renal intermediary metabolism and the onset of renal dysfunction in the streptozotocin diabetic rat.
    Biochemical Society transactions, 1996, Volume: 24, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies;

1996
Potential of the monoglyceride and triglyceride of DL-3-hydroxybutyrate for parenteral nutrition: synthesis and preliminary biological testing in the rat.
    Nutrition (Burbank, Los Angeles County, Calif.), 1997, Volume: 13, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animal Nutritional Physiological Phenomena; Animals; Body Weight; Cohort Stud

1997
Metabolic adaptation to experimentally increased glucose demand in ruminants.
    Journal of animal science, 1998, Volume: 76, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Urea Nitrogen; Disease Models, Animal; Fatty Ac

1998
Hypoglycemic effects of a beta-agonist, Ro 16-8714, in streptozotocin-diabetic rats: decreased hepatic glucose production and increased glucose utilization in oxidative muscles.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:2

    Topics: 2-Hydroxyphenethylamine; 3-Hydroxybutyric Acid; Adrenergic beta-Agonists; Animals; Diabetes Mellitus

1992
Reappraisal of the role of insulin on sodium handling by the kidney: f1fect of intrarenal insulin infusion in the dog.
    European journal of clinical investigation, 1992, Volume: 22, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Pressure; Dogs; Fatty Acids, Nonesterified; Fem

1992
New test for urinary glucose (BM33071) evaluated.
    Clinical chemistry, 1985, Volume: 31, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Ascorbic Acid; Evaluation Studies as Topic; Glucosephosphate D

1985