3-hydroxybutyric acid has been researched along with Glioma in 10 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 6 (60.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Javier, R | 1 |
| Wang, W | 1 |
| Drumm, M | 1 |
| McCortney, K | 1 |
| Sarkaria, JN | 1 |
| Horbinski, C | 1 |
| Woodhouse, C | 1 |
| Ward, T | 1 |
| Gaskill-Shipley, M | 1 |
| Chaudhary, R | 1 |
| Yang, N | 1 |
| Tanner, JA | 1 |
| Zheng, BJ | 1 |
| Watt, RM | 1 |
| He, ML | 1 |
| Lu, LY | 1 |
| Jiang, JQ | 1 |
| Shum, KT | 1 |
| Lin, YP | 1 |
| Wong, KL | 1 |
| Lin, MCM | 1 |
| Kung, HF | 1 |
| Sun, H | 1 |
| Huang, JD | 1 |
| Marinho, CC | 1 |
| Nicolato, AJPG | 1 |
| Reis, VW | 1 |
| Dos Santos, RC | 1 |
| Silva, JC | 1 |
| Faria, HP | 1 |
| Machado-Coelho, GLL | 1 |
| Sun, Y | 2 |
| Zhang, N | 1 |
| Wang, J | 2 |
| Guo, Y | 1 |
| Sun, B | 1 |
| Liu, W | 1 |
| Zhou, H | 1 |
| Yang, C | 1 |
| Wei, L | 1 |
| Ball, S | 1 |
| Dennis, JA | 1 |
| Bedanie, G | 1 |
| Nugent, K | 1 |
| Hayek, AJ | 1 |
| Scott, V | 1 |
| Yau, P | 1 |
| Zolfaghari, K | 1 |
| Goldwater, M | 1 |
| Almquist, J | 1 |
| Arroliga, AC | 1 |
| Ghamande, S | 1 |
| Wu, Q | 1 |
| Ma, W | 1 |
| Shi, R | 1 |
| Zhang, B | 1 |
| Mao, X | 1 |
| Zheng, W | 1 |
| Sbhatu, DB | 1 |
| Berhe, GG | 1 |
| Hndeya, AG | 1 |
| Abraha, HB | 1 |
| Abdu, A | 1 |
| Gebru, HA | 1 |
| Taye, MG | 1 |
| Mulugeta, A | 1 |
| Weldemichael, MY | 1 |
| Tekle, HT | 1 |
| Kidanemariam, HG | 1 |
| Surger, M | 1 |
| Angelov, A | 1 |
| Liebl, W | 1 |
| Hookey, L | 1 |
| Bertiger, G | 1 |
| Johnson, KL | 1 |
| Boules, M | 1 |
| Ando, M | 1 |
| Dahdal, DN | 1 |
| Riedl, JM | 1 |
| Posch, F | 1 |
| Prager, G | 1 |
| Eisterer, W | 1 |
| Oehler, L | 1 |
| Sliwa, T | 1 |
| Wilthoner, K | 1 |
| Petzer, A | 1 |
| Pichler, P | 1 |
| Hubmann, E | 1 |
| Winder, T | 1 |
| Burgstaller, S | 1 |
| Korger, M | 1 |
| Andel, J | 1 |
| Greil, R | 1 |
| Neumann, HJ | 1 |
| Pecherstorfer, M | 1 |
| Philipp-Abbrederis, K | 1 |
| Djanani, A | 1 |
| Gruenberger, B | 1 |
| Laengle, F | 1 |
| Wöll, E | 1 |
| Gerger, A | 1 |
| Evans, WE | 1 |
| Raynor, HA | 1 |
| Howie, W | 1 |
| Lipton, RB | 1 |
| Thomas, GJ | 1 |
| Wing, RR | 1 |
| Pavlovic, J | 1 |
| Farris, SG | 1 |
| Bond, DS | 1 |
| Hepprich, M | 1 |
| Antwi, K | 1 |
| Waser, B | 1 |
| Reubi, JC | 1 |
| Wild, D | 1 |
| Christ, ER | 1 |
| Braüner Christensen, J | 1 |
| Aasbrenn, M | 1 |
| Sandoval Castillo, L | 1 |
| Ekmann, A | 1 |
| Giver Jensen, T | 1 |
| Pressel, E | 1 |
| Haxholdt Lunn, T | 1 |
| Suetta, C | 1 |
| Palm, H | 1 |
| Mansour, FA | 1 |
| Al-Mazrou, A | 1 |
| Al-Mohanna, F | 1 |
| Al-Alwan, M | 1 |
| Ghebeh, H | 1 |
| Brown-Johnson, C | 1 |
| Safaeinili, N | 1 |
| Zionts, D | 1 |
| Holdsworth, LM | 1 |
| Shaw, JG | 1 |
| Asch, SM | 1 |
| Mahoney, M | 1 |
| Winget, M | 1 |
| Luo, Y | 1 |
| Shan, H | 1 |
| Gao, X | 1 |
| Qi, P | 1 |
| Li, Y | 2 |
| Li, B | 1 |
| Rong, X | 1 |
| Shen, B | 1 |
| Zhang, H | 1 |
| Lin, F | 1 |
| Tang, Z | 1 |
| Fang, Z | 1 |
| Peng, Z | 1 |
| Jimenez, JL | 1 |
| Ayer, GB | 1 |
| Klepov, VV | 1 |
| Pace, KA | 1 |
| Zur Loye, HC | 1 |
| Acquaroni, M | 1 |
| Svartz, G | 1 |
| Pérez Coll, C | 1 |
| Otludil, B | 1 |
| Ayaz, S | 1 |
| Hill, A | 1 |
| Elakkad, A | 1 |
| Kuban, J | 1 |
| Sabir, S | 1 |
| Odisio, B | 1 |
| Huang, SY | 1 |
| Mahvash, A | 1 |
| Miller, E | 1 |
| Kroll, MH | 1 |
| Overman, M | 1 |
| Tam, AL | 1 |
| Gupta, S | 1 |
| Sheth, RA | 1 |
| Deandreis, D | 1 |
| Guarneri, A | 1 |
| Ceci, F | 1 |
| Lillaz, B | 1 |
| Bartoncini, S | 1 |
| Oderda, M | 1 |
| Nicolotti, DG | 1 |
| Pilati, E | 1 |
| Passera, R | 1 |
| Zitella, A | 1 |
| Bellò, M | 1 |
| Parise, R | 1 |
| Carlevato, R | 1 |
| Ricardi, U | 1 |
| Gontero, P | 1 |
| Coyne, GO' | 1 |
| Wang, L | 3 |
| Zlott, J | 1 |
| Juwara, L | 1 |
| Covey, JM | 1 |
| Beumer, JH | 1 |
| Cristea, MC | 1 |
| Newman, EM | 1 |
| Koehler, S | 1 |
| Nieva, JJ | 1 |
| Garcia, AA | 1 |
| Gandara, DR | 1 |
| Miller, B | 1 |
| Khin, S | 1 |
| Miller, SB | 1 |
| Steinberg, SM | 1 |
| Rubinstein, L | 1 |
| Parchment, RE | 1 |
| Kinders, RJ | 1 |
| Piekarz, RL | 1 |
| Kummar, S | 1 |
| Chen, AP | 1 |
| Doroshow, JH | 1 |
| Li, X | 2 |
| Chen, J | 2 |
| Gan, L | 1 |
| Tian, Y | 1 |
| Shi, B | 1 |
| Yang, Y | 1 |
| Li, G | 1 |
| Wu, D | 1 |
| Wen, A | 1 |
| Wu, Y | 1 |
| Zhou, X | 1 |
| Koyappayil, A | 1 |
| Chavan, SG | 1 |
| Mohammadniaei, M | 1 |
| Go, A | 1 |
| Hwang, SY | 1 |
| Lee, MH | 1 |
| Kurokawa, Y | 1 |
| Yamashita, K | 1 |
| Kawabata, R | 1 |
| Fujita, J | 1 |
| Imamura, H | 1 |
| Takeno, A | 1 |
| Takahashi, T | 1 |
| Yamasaki, M | 1 |
| Eguchi, H | 1 |
| Doki, Y | 1 |
| Schulte, T | 1 |
| Sala, BM | 1 |
| Nilvebrant, J | 1 |
| Nygren, PÅ | 1 |
| Achour, A | 1 |
| Shernyukov, A | 1 |
| Agback, T | 1 |
| Agback, P | 1 |
| Karami, H | 1 |
| Shariatifar, N | 1 |
| Nazmara, S | 1 |
| Moazzen, M | 1 |
| Mahmoodi, B | 1 |
| Mousavi Khaneghah, A | 1 |
| Sinha, N | 1 |
| Mukhopadhyay, S | 1 |
| Sau, M | 1 |
| Qi, Y | 1 |
| Wan, M | 1 |
| Abd El-Aty, AM | 1 |
| Li, H | 2 |
| Cao, L | 1 |
| She, Y | 1 |
| Shao, Y | 1 |
| Jin, F | 1 |
| Wang, S | 1 |
| Melendez-Araújo, MS | 1 |
| Lemos, KGE | 1 |
| Arruda, SLM | 1 |
| Dutra, ES | 1 |
| de Carvalho, KMB | 1 |
| de la Plaza Llamas, R | 1 |
| Díaz Candelas, DA | 1 |
| Ramia, JM | 1 |
| Zhu, S | 1 |
| Liu, Z | 1 |
| Lu, J | 2 |
| Xiang, Z | 1 |
| Lan, J | 1 |
| Liu, J | 1 |
| Yu, M | 1 |
| Chen, Y | 2 |
| Sirajudeen, AAO | 1 |
| Annuar, MSM | 1 |
| Subramaniam, R | 1 |
| Somme, F | 1 |
| Montaz-Rosset, MS | 1 |
| Averous, G | 1 |
| Deur, J | 1 |
| Goichot, B | 1 |
| Bachellier, P | 1 |
| Addeo, P | 1 |
| Imperiale, A | 1 |
| Xu, L | 1 |
| Li, Z | 2 |
| Song, S | 1 |
| Chen, Q | 1 |
| Mo, L | 1 |
| Wang, C | 1 |
| Fan, W | 1 |
| Yan, Y | 1 |
| Tong, X | 1 |
| Yan, H | 1 |
| Singh, A | 1 |
| Chen, HC | 1 |
| Chen, YF | 1 |
| Lu, YJ | 1 |
| Wong, KT | 1 |
| Chu, CW | 1 |
| Banijamali, AR | 1 |
| Carvalho, AE | 1 |
| Wakefield, JD | 1 |
| Germano, P | 1 |
| Barden, TC | 1 |
| Tobin, JV | 1 |
| Zimmer, DP | 1 |
| Masferrer, JL | 1 |
| Profy, AT | 1 |
| Currie, MG | 1 |
| Todd Milne, G | 1 |
| Zhang, Y | 2 |
| Yang, H | 1 |
| Dang, Z | 1 |
| Zhan, S | 1 |
| Sun, C | 1 |
| Hu, G | 1 |
| Lin, Y | 1 |
| Yuan, Q | 1 |
| Karayağiz Muslu, G | 1 |
| Özdemir, M | 1 |
| Del Prete, S | 1 |
| Nocentini, A | 1 |
| Supuran, CT | 1 |
| Capasso, C | 1 |
| Chagas, ATA | 1 |
| Ludwig, S | 1 |
| Pimentel, JDSM | 1 |
| de Abreu, NL | 1 |
| Nunez-Rodriguez, DL | 1 |
| Leal, HG | 1 |
| Kalapothakis, E | 1 |
| Zhang, J | 1 |
| Lin, L | 1 |
| Dodig, D | 1 |
| Kovačić, S | 1 |
| Matana Kaštelan, Z | 1 |
| Žuža, I | 1 |
| Benić, F | 1 |
| Slaven, J | 1 |
| Miletić, D | 1 |
| Rumboldt, Z | 1 |
| Fernandez-Botran, R | 1 |
| Wellmann, IA | 1 |
| Une, C | 1 |
| Méndez-Chacón, E | 1 |
| Hernández de Rodas, E | 1 |
| Bhandari, B | 1 |
| Villagrán de Tercero, CI | 1 |
| Nguyen, HTT | 1 |
| Romano, F | 1 |
| Wampfler, R | 1 |
| Mühlethaler, K | 1 |
| Tannich, E | 1 |
| Oberli, A | 1 |
| Yang, J | 1 |
| Xiang, T | 1 |
| Dai, L | 1 |
| Zhao, X | 1 |
| Ma, L | 1 |
| Zuo, D | 1 |
| Wei, B | 1 |
| Sui, Y | 1 |
| Xu, F | 1 |
| Zheng, H | 1 |
| Qiu, C | 1 |
| Jin, H | 1 |
| Kerwin, J | 1 |
| Khan, I | 1 |
| Rajasekhar, B | 1 |
| Venkateshwaran, U | 1 |
| Durairaj, N | 1 |
| Divyapriya, G | 1 |
| Nambi, IM | 1 |
| Joseph, A | 1 |
| Aliste, M | 1 |
| Garrido, I | 1 |
| Flores, P | 1 |
| Hellín, P | 1 |
| Vela, N | 1 |
| Navarro, S | 1 |
| Fenoll, J | 1 |
| Shang, S | 1 |
| Lu, H | 1 |
| Lu, X | 1 |
| Jiang, YS | 1 |
| Wang, FR | 1 |
| De Feyter, HM | 1 |
| Behar, KL | 1 |
| Rao, JU | 1 |
| Madden-Hennessey, K | 1 |
| Ip, KL | 1 |
| Hyder, F | 1 |
| Drewes, LR | 1 |
| Geschwind, JF | 1 |
| de Graaf, RA | 1 |
| Rothman, DL | 1 |
| Maurer, GD | 1 |
| Brucker, DP | 1 |
| Bähr, O | 1 |
| Harter, PN | 1 |
| Hattingen, E | 1 |
| Walenta, S | 1 |
| Mueller-Klieser, W | 1 |
| Steinbach, JP | 1 |
| Rieger, J | 1 |
| Abdelwahab, MG | 1 |
| Fenton, KE | 1 |
| Preul, MC | 1 |
| Rho, JM | 1 |
| Lynch, A | 1 |
| Stafford, P | 1 |
| Scheck, AC | 1 |
| Patel, MS | 2 |
| Russell, JJ | 1 |
| Gershman, H | 1 |
| Haney, PM | 1 |
| Bolinger, L | 1 |
| Raefsky, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma[NCT05119010] | 60 participants (Anticipated) | Interventional | 2023-03-24 | Recruiting | |||
| Phase I/II Prospective Trial for Newly Diagnosed GBM, With Upfront Gross or Subtotal Resection, Followed by Ketogenic Diet With Radiotherapy and Concurrent Temodar(R) Chemotherapy Followed by Adjuvant Temodar(R) Chemotherapy.[NCT02046187] | Phase 1/Phase 2 | 14 participants (Actual) | Interventional | 2013-10-31 | Terminated (stopped due to excessive protocol deviations due to strict nature of diet requirements) | ||
| A Modified Ketogenic, Anti-Inflammatory Diet for Patients With High-Grade Gliomas[NCT05373381] | 10 participants (Anticipated) | Interventional | 2022-05-18 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for 3-hydroxybutyric acid and Glioma
9 other studies available for 3-hydroxybutyric acid and Glioma
| Article | Year |
|---|---|
The efficacy of an unrestricted cycling ketogenic diet in preclinical models of IDH wild-type and IDH mutant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cell Line, Tumor; Cell Proliferation; Diet, Ketogenic | 2022 |
Feasibility of a modified Atkins diet in glioma patients during radiation and its effect on radiation sensitization.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Brain Neoplasms; Diet, Ketogenic; Feasibility Studies; Female; G | 2019 |
The Beta-Hydroxybutyrate Suppresses the Migration of Glioma Cells by Inhibition of NLRP3 Inflammasome.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Move | 2018 |
Caloric restriction reduces edema and prolongs survival in a mouse glioma model.
Topics: 3-Hydroxybutyric Acid; Animals; Brain Edema; Brain Neoplasms; Caloric Restriction; Cell Line, Tumor; | 2013 |
A ketogenic diet increases transport and oxidation of ketone bodies in RG2 and 9L gliomas without affecting tumor growth.
Topics: 3-Hydroxybutyric Acid; Animals; Brain Neoplasms; Cell Line, Tumor; Diet, Ketogenic; Disease Models, | 2016 |
Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy.
Topics: 3-Hydroxybutyric Acid; Acetyl-CoA C-Acetyltransferase; Animals; Animals, Newborn; Cell Line, Tumor; | 2011 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain; Combined Modality Therapy; Diet, Ketogenic; Di | 2012 |
Ketone-body metabolism in glioma and neuroblastoma cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetyl-CoA C-Acetyltransferase; Animals; Cell Line; Coenzyme A | 1981 |
Turnover of succinyl-CoA:3-oxoacid CoA-transferase in glioma and neuroblastoma cells. Specific influence of acetoacetate in neuroblastoma cells.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Cell Line; Coenzyme A-Transferases; Electrophoresis, | 1984 |