3-hydroxybutyric acid has been researched along with Genetic Predisposition in 8 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metabolic diseases included clinical ketosis (KET) and displaced abomasum (DA); fertility disorders were metritis (MET) and retained placenta (RP); and disease indicators were fat-to-protein ratio, milk β-hydroxybutyrate, and body condition score (BCS) in the first lactation." | 1.43 | Multiple-trait estimates of genetic parameters for metabolic disease traits, fertility disorders, and their predictors in Canadian Holsteins. ( Jamrozik, J; Kistemaker, GJ; Koeck, A; Miglior, F, 2016) |
| "Our results suggest that genetic susceptibility plays an important role in inducing underdevelopment and NTD in cultured CDs embryos in sub-teratogenic medium and in protecting the CDr embryos under the same conditions." | 1.32 | Reduced SOD activity and increased neural tube defects in embryos of the sensitive but not of the resistant Cohen diabetic rats cultured under diabetic conditions. ( Ornoy, A; Weksler-Zangen, S; Yaffe, P, 2003) |
| "The level of ketosis, however, was not predictive of seizure protection in EL mice." | 1.31 | The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy. ( Madore, RA; Seyfried, TN; Stafstrom, CE; Tandon, P; Todorova, MT, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Luukkonen, PK | 1 |
| Porthan, K | 1 |
| Ahlholm, N | 1 |
| Rosqvist, F | 1 |
| Dufour, S | 1 |
| Zhang, XM | 1 |
| Lehtimäki, TE | 1 |
| Seppänen, W | 1 |
| Orho-Melander, M | 1 |
| Hodson, L | 1 |
| Petersen, KF | 1 |
| Shulman, GI | 1 |
| Yki-Järvinen, H | 1 |
| Pralle, RS | 1 |
| Schultz, NE | 1 |
| White, HM | 1 |
| Weigel, KA | 1 |
| Bouvier-Muller, J | 1 |
| Allain, C | 1 |
| Enjalbert, F | 1 |
| Farizon, Y | 1 |
| Portes, D | 1 |
| Foucras, G | 1 |
| Rupp, R | 1 |
| Duehlmeier, R | 1 |
| Noldt, S | 1 |
| Ganter, M | 1 |
| Jamrozik, J | 1 |
| Koeck, A | 1 |
| Kistemaker, GJ | 1 |
| Miglior, F | 1 |
| Weksler-Zangen, S | 1 |
| Yaffe, P | 1 |
| Ornoy, A | 1 |
| Todorova, MT | 1 |
| Tandon, P | 1 |
| Madore, RA | 1 |
| Stafstrom, CE | 1 |
| Seyfried, TN | 1 |
| Rho, JM | 1 |
| Anderson, GD | 1 |
| Donevan, SD | 1 |
| White, HS | 1 |
8 other studies available for 3-hydroxybutyric acid and Genetic Predisposition
| Article | Year |
|---|---|
The PNPLA3 I148M variant increases ketogenesis and decreases hepatic de novo lipogenesis and mitochondrial function in humans.
Topics: 3-Hydroxybutyric Acid; Genetic Predisposition to Disease; Humans; Lipogenesis; Liver; Mitochondria; | 2023 |
Hyperketonemia GWAS and parity-dependent SNP associations in Holstein dairy cows intensively sampled for blood β-hydroxybutyrate concentration.
Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Female; Genes; Genetic Predisposition to Di | 2020 |
Somatic cell count-based selection reduces susceptibility to energy shortage during early lactation in a sheep model.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Body Weight; Cell Count; Energy Metabolism; Fatty Ac | 2018 |
Pancreatic insulin release and peripheral insulin sensitivity in German black headed mutton and Finish Landrace ewes: evaluation of the role of insulin resistance in the susceptibility to ovine pregnancy toxemia.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Fatty Acids, Nonesterified; Female; Genetic Predispos | 2013 |
Multiple-trait estimates of genetic parameters for metabolic disease traits, fertility disorders, and their predictors in Canadian Holsteins.
Topics: 3-Hydroxybutyric Acid; Animals; Bayes Theorem; Canada; Cattle; Cattle Diseases; Female; Fertility; G | 2016 |
Reduced SOD activity and increased neural tube defects in embryos of the sensitive but not of the resistant Cohen diabetic rats cultured under diabetic conditions.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Catalase; Diabetes Mellitus, Type 2; Disease Models, | 2003 |
The ketogenic diet inhibits epileptogenesis in EL mice: a genetic model for idiopathic epilepsy.
Topics: 3-Hydroxybutyric Acid; Animals; Association Learning; Behavior, Animal; Blood Glucose; Dietary Carbo | 2000 |
Acetoacetate, acetone, and dibenzylamine (a contaminant in l-(+)-beta-hydroxybutyrate) exhibit direct anticonvulsant actions in vivo.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Animals; Anticonvulsants; Benzylamines; Drug Contamin | 2002 |