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3-hydroxybutyric acid and Epilepsy, Absence

3-hydroxybutyric acid has been researched along with Epilepsy, Absence in 3 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Epilepsy, Absence: A seizure disorder usually occurring in childhood characterized by rhythmic electrical brain discharges of generalized onset. Clinical features include a sudden cessation of ongoing activity usually without loss of postural tone. Rhythmic blinking of the eyelids or lip smacking frequently accompanies the SEIZURES. The usual duration is 5-10 seconds, and multiple episodes may occur daily. Juvenile absence epilepsy is characterized by the juvenile onset of absence seizures and an increased incidence of myoclonus and tonic-clonic seizures. (Menkes, Textbook of Child Neurology, 5th ed, p736)

Research Excerpts

ExcerptRelevanceReference
"KEKS-supplemented food-generated ketosis may increase adenosine levels, and may thus modulate both neuroinflammatory processes and epileptic activity through adenosine receptors (such as A1Rs and A2ARs)."1.62Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats. ( Ari, C; Brunner, B; D'Agostino, DP; Kovács, Z, 2021)
" In this study, we tested the changes in blood glucose and ketone (βHB) levels in response to acute, sub-chronic, and chronic administration of various ketogenic compounds in either a post-exercise or rested state."1.51Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models. ( Ari, C; Bharwani, S; D'Agostino, DP; Diamond, DM; Goldhagen, CR; Kindy, MS; Koutnik, AP; Kovács, Z; Murdun, C; Park, C; Rogers, C, 2019)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Brunner, B1
Ari, C2
D'Agostino, DP2
Kovács, Z2
Murdun, C1
Koutnik, AP1
Goldhagen, CR1
Rogers, C1
Park, C1
Bharwani, S1
Diamond, DM1
Kindy, MS1
Nehlig, A1
Dufour, F1
Klinger, M1
Willing, LB1
Simpson, IA1
Vannucci, SJ1

Other Studies

3 other studies available for 3-hydroxybutyric acid and Epilepsy, Absence

ArticleYear
Adenosine Receptors Modulate the Exogenous Ketogenic Supplement-Evoked Alleviating Effect on Lipopolysaccharide-Generated Increase in Absence Epileptic Activity in WAG/Rij Rats.
    Nutrients, 2021, Nov-15, Volume: 13, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Dietary Supplements; Disease Models, Ani

2021
Exogenous Ketones Lower Blood Glucose Level in Rested and Exercised Rodent Models.
    Nutrients, 2019, Oct-01, Volume: 11, Issue:10

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Biomarkers; Blood Glucose; Butylene Glycols; Carbohyd

2019
The ketogenic diet has no effect on the expression of spike-and-wave discharges and nutrient transporters in genetic absence epilepsy rats from Strasbourg.
    Journal of neurochemistry, 2009, Volume: 109 Suppl 1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood-Brain Barrier; Electroencephalography; Epilepsy

2009