Page last updated: 2024-10-17

3-hydroxybutyric acid and Endometritis

3-hydroxybutyric acid has been researched along with Endometritis in 33 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Endometritis: Inflammation of the ENDOMETRIUM, usually caused by intrauterine infections. Endometritis is the most common cause of postpartum fever.

Research Excerpts

ExcerptRelevanceReference
"In cases of ketosis, a decrease in activity may be observed 5 days before the clinical diagnosis is made."2.61[Overview on the relationship between changes in activity and ketosis in dairy cows]. ( Hajek, F; Mansfeld, R, 2019)
"Cows with ketosis had also greater postpartum serum concentrations of NEFA, BHB, GGT and aspartate transaminase (AST) when compared with control cows."1.62Common and specific mineral and metabolic features in dairy cows with clinical metritis, hypocalcaemia or ketosis. ( Colazo, M; Dervishi, E; Hoff, B; Plastow, G, 2021)
"The urea concentration was significantly lower (P < 0."1.62Comparative biochemical profiles, utero-ovarian function, and fertility of the postpartum buffalo with and without subclinical endometritis. ( Jan, MH; Kumar, H; Kumar, S; Malla, WA; Sharma, RK, 2021)
"Pregnancy was diagnosed on d 31 and 59 of presumptive gestation."1.56Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer. ( Bromfield, JJ; Edelhoff, INF; Pereira, MHC; Santos, JEP; Vasconcelos, JLM, 2020)
"Clinical endometritis was diagnosed by observation of vaginal discharges (>50% pus), and subclinical endometritis was diagnosed by evaluation of uterine cytology (>18% neutrophils) at 4 weeks postpartum."1.42Relationships among ketosis, serum metabolites, body condition, and reproductive outcomes in dairy cows. ( Choi, IS; Hur, TY; Jeong, JK; Jung, YH; Kang, HG; Kim, IH; Shin, EK, 2015)
"Subclinical ketosis (SCK) is defined as concentrations of β-hydroxybutyrate (BHBA) ≥ 1."1.39Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows. ( Canelas-Raposo, J; Deniz, A; Heuwieser, W; Suthar, VS, 2013)
"Last, clinical endometritis has detrimental effects on reproductive efficiency, as affected cows take longer to get pregnant and are at higher risk for culling."1.39Clinical endometritis in an Argentinean herd of dairy cows: risk factors and reproductive efficiency. ( Becu-Villalobos, D; de la Sota, RL; Giuliodori, MJ; Lacau-Mengido, IM; Magnasco, RP; Risco, CA, 2013)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (9.09)29.6817
2010's22 (66.67)24.3611
2020's8 (24.24)2.80

Authors

AuthorsStudies
Zinicola, M3
Bicalho, MLS1
Santin, T1
Marques, EC1
Bisinotto, RS1
Bicalho, RC3
Sahar, MW1
Beaver, A1
Weary, DM1
von Keyserlingk, MAG1
Hajek, F1
Mansfeld, R1
LeBlanc, SJ2
de Oliveira, EB1
Cunha, F2
Daetz, R2
Figueiredo, CC1
Chebel, RC2
Santos, JE2
Risco, CA3
Jeong, KC2
Machado, VS3
Galvão, KN3
Celestino, ML1
Oliveira, EB1
Lima, FS1
Ballou, MA1
Edelhoff, INF1
Pereira, MHC1
Bromfield, JJ1
Vasconcelos, JLM1
Santos, JEP2
Dervishi, E1
Plastow, G1
Hoff, B1
Colazo, M1
Jan, MH1
Kumar, H1
Kumar, S1
Malla, WA1
Sharma, RK1
Pinedo, P1
Manríquez, D1
Marotta, N1
Mongiello, G1
Risco, C1
Leenaerts, L1
Bothe, H1
Velez, J1
Ruprechter, G1
Adrien, ML1
Larriestra, A1
Meotti, O1
Batista, C1
Meikle, A1
Noro, M1
Umaña Sedó, S1
Rosa, D1
Mattioli, G1
Luzbel de la Sota, R1
Giuliodori, MJ2
Korzec, H1
Teixeira, AGV1
Ganda, EK2
Bringhenti, L1
Tomazi, ACCH1
Gilbert, RO3
Suthar, VS1
Canelas-Raposo, J1
Deniz, A1
Heuwieser, W4
Yasui, T1
McCann, K1
Nydam, DV1
Overton, TR1
Silva, PR1
Dresch, AR1
Machado, KS1
Moraes, JG1
Lobeck-Luchterhand, K1
Nishimura, TK1
Ferreira, MA1
Endres, MI1
Oikonomou, G1
Stephens, L1
Milhomem, M1
Freitas, GL1
Pearson, J1
Wieland, M1
Guard, C1
Shin, EK1
Jeong, JK1
Choi, IS1
Kang, HG1
Hur, TY1
Jung, YH1
Kim, IH1
Pohl, A1
Burfeind, O1
Burnett, TA1
Madureira, AM1
Silper, BF1
Tahmasbi, A1
Nadalin, A1
Veira, DM1
Cerri, RL1
Ghanem, ME1
Tezuka, E1
Sasaki, K1
Takahashi, M1
Yamagishi, N1
Izaike, Y2
Osawa, T2
Stangaferro, ML1
Wijma, R1
Caixeta, LS1
Al-Abri, MA1
Giordano, JO1
Bittar, JH1
Magalhaes, F1
Maeda, Y1
Cooke, RF1
Abdelli, A1
Raboisson, D1
Kaidi, R1
Ibrahim, B1
Kalem, A1
Iguer-Ouada, M1
Arlt, S1
Padberg, W1
Drillich, M2
Hässig, M1
Steinmann, B1
Wittenbrink, MM1
Kaufmann, TB1
Tenhagen, BA1
Senosy, WS1
Chapinal, N1
Carson, ME1
Leslie, KE1
Godden, S1
Capel, M1
Overton, MW1
Duffield, TF1
Heidarpour, M1
Mohri, M1
Fallah-Rad, AH1
Dehghan Shahreza, F1
Mohammadi, M1
Magnasco, RP1
Becu-Villalobos, D1
Lacau-Mengido, IM1
de la Sota, RL1
Nocek, JE1
Kautz, WP1
Hammon, DS1
Evjen, IM1
Dhiman, TR1
Goff, JP1
Walters, JL1

Reviews

3 reviews available for 3-hydroxybutyric acid and Endometritis

ArticleYear
[Overview on the relationship between changes in activity and ketosis in dairy cows].
    Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 2019, Volume: 47, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Behavior, Animal; Cattle; Cattle Diseases; Diagnosis,

2019
Review: Relationships between metabolism and neutrophil function in dairy cows in the peripartum period.
    Animal : an international journal of animal bioscience, 2020, Volume: 14, Issue:S1

    Topics: 3-Hydroxybutyric Acid; Adaptation, Physiological; Animals; Cattle; Cattle Diseases; Endometritis; En

2020
Elevated non-esterified fatty acid and β-hydroxybutyrate in transition dairy cows and their association with reproductive performance and disorders: A meta-analysis.
    Theriogenology, 2017, Apr-15, Volume: 93

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Dairying; Endometritis; Estrous Cycle; Fatt

2017

Trials

6 trials available for 3-hydroxybutyric acid and Endometritis

ArticleYear
Effects of recombinant bovine interleukin-8 (rbIL-8) treatment on health, metabolism, and lactation performance in Holstein cattle II: Postpartum uterine health, ketosis, and milk production.
    Journal of dairy science, 2019, Volume: 102, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Chemotaxis; Endometritis; Female; Fermentat

2019
Using chitosan microparticles to treat metritis in lactating dairy cows.
    Journal of dairy science, 2020, Volume: 103, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Cephalosporins; Chit

2020
The association of cow-related factors assessed at metritis diagnosis with metritis cure risk, reproductive performance, milk yield, and culling for untreated and ceftiofur-treated dairy cows.
    Journal of dairy science, 2020, Volume: 103, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Bacterial Agents; Cattle; Cattle Diseases; Cephalosporins; Coho

2020
Prepartum stocking density: effects on metabolic, health, reproductive, and productive responses.
    Journal of dairy science, 2014, Volume: 97, Issue:9

    Topics: 3-Hydroxybutyric Acid; Animals; Behavior, Animal; Cattle; Cattle Diseases; Cell Count; Endometritis;

2014
Clinical response after chitosan microparticle administration and preliminary assessment of efficacy in preventing metritis in lactating dairy cows.
    Journal of dairy science, 2016, Volume: 99, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Body Temperature; Cattle; Cattle Diseases; Chitosan; Dose-Response R

2016
Efficacy of homeopathic remedies as prophylaxis of bovine endometritis.
    Journal of dairy science, 2009, Volume: 92, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Double-Blind Method; Endometritis; Fatty Ac

2009

Other Studies

24 other studies available for 3-hydroxybutyric acid and Endometritis

ArticleYear
Feeding behavior and agonistic interactions at the feed bunk are associated with hyperketonemia and metritis diagnosis in dairy cattle.
    Journal of dairy science, 2020, Volume: 103, Issue:1

    Topics: 3-Hydroxybutyric Acid; Agonistic Behavior; Animal Feed; Animal Husbandry; Animals; Cattle; Cattle Di

2020
Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer.
    Journal of dairy science, 2020, Volume: 103, Issue:12

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Embryo Transfer; Endometritis; Female; Fert

2020
Common and specific mineral and metabolic features in dairy cows with clinical metritis, hypocalcaemia or ketosis.
    Research in veterinary science, 2021, Volume: 135

    Topics: 3-Hydroxybutyric Acid; Alberta; Animals; Aspartate Aminotransferases; Cattle; Cattle Diseases; Chole

2021
Comparative biochemical profiles, utero-ovarian function, and fertility of the postpartum buffalo with and without subclinical endometritis.
    Tropical animal health and production, 2021, Jan-05, Volume: 53, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Buffaloes; Calcium; Endometritis; Endometrium; Female

2021
Effect of oral calcium administration on metabolic status and uterine health of dairy cows with reduced postpartum rumination and eating time.
    BMC veterinary research, 2021, Apr-29, Volume: 17, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Calcium; Cattle; Cattle Diseases; Dairying; Dietary Supplements; End

2021
Metabolic predictors of peri-partum diseases and their association with parity in dairy cows.
    Research in veterinary science, 2018, Volume: 118

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Endometritis; Fatty Acids, Nonesterified; F

2018
Associations of subclinical hypocalcemia with fertility in a herd of grazing dairy cows.
    Journal of dairy science, 2018, Volume: 101, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Argentina; Calcium; Cattle; Cattle Diseases; Endometritis; Female; F

2018
Effects of pegbovigrastim administration on periparturient diseases, milk production, and reproductive performance of Holstein cows.
    Journal of dairy science, 2018, Volume: 101, Issue:12

    Topics: 3-Hydroxybutyric Acid; Animals; Anti-Inflammatory Agents; Cattle; Cattle Diseases; Colostrum; Endome

2018
Prevalence of subclinical ketosis and relationships with postpartum diseases in European dairy cows.
    Journal of dairy science, 2013, Volume: 96, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Comorbidity; Endometritis; Europe; Female;

2013
Associations of cytological endometritis with energy metabolism and inflammation during the periparturient period and early lactation in dairy cows.
    Journal of dairy science, 2014, Volume: 97, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Endometritis; Energy Metabolism; Fatty Acid

2014
The effect of intrauterine infusion of dextrose on clinical endometritis cure rate and reproductive performance of dairy cows.
    Journal of dairy science, 2015, Volume: 98, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Anovulation; Cattle; Cattle Diseases; Endometritis; Female; Glucose;

2015
Relationships among ketosis, serum metabolites, body condition, and reproductive outcomes in dairy cows.
    Theriogenology, 2015, Jul-15, Volume: 84, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Aspartate Aminotransferases; Blood Glucose; Blood Urea Nitrogen; Bod

2015
The associations between postpartum serum haptoglobin concentration and metabolic status, calving difficulties, retained fetal membranes, and metritis.
    Journal of dairy science, 2015, Volume: 98, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Body Temperature; Cattle; Cattle Diseases; Dystocia; Endometritis; E

2015
Relationship of concentrations of cortisol in hair with health, biomarkers in blood, and reproductive status in dairy cows.
    Journal of dairy science, 2015, Volume: 98, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Cattle; Endometritis; Female; Hair; Hydrocortisone; Milk

2015
Correlation of blood metabolite concentrations and body condition scores with persistent postpartum uterine bacterial infection in dairy cows.
    The Journal of reproduction and development, 2016, Oct-18, Volume: 62, Issue:5

    Topics: 3-Hydroxybutyric Acid; Actinomycetaceae; Animals; Blood Glucose; Blood Urea Nitrogen; Cattle; Cattle

2016
Use of rumination and activity monitoring for the identification of dairy cows with health disorders: Part III. Metritis.
    Journal of dairy science, 2016, Volume: 99, Issue:9

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Endometritis; Female; Ketosis; Lactation; P

2016
[Benefit of clinical and laboratory parameters for the diagnosis of endometritis in dairy cows].
    Schweizer Archiv fur Tierheilkunde, 2010, Volume: 152, Issue:9

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Endometritis; Escherichia coli Infections; False Negative Re

2010
Correlations between periparturient serum concentrations of non-esterified fatty acids, beta-hydroxybutyric acid, bilirubin, and urea and the occurrence of clinical and subclinical postpartum bovine endometritis.
    BMC veterinary research, 2010, Oct-27, Volume: 6

    Topics: 3-Hydroxybutyric Acid; Animals; Bilirubin; Cattle; Cattle Diseases; Endometritis; Fatty Acids, Nones

2010
Influences of metabolic traits on subclinical endometritis at different intervals postpartum in high milking cows.
    Reproduction in domestic animals = Zuchthygiene, 2012, Volume: 47, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Urea Nitrogen; Body Composition; Cattle; Cattle

2012
Herd-level association of serum metabolites in the transition period with disease, milk production, and early lactation reproductive performance.
    Journal of dairy science, 2012, Volume: 95, Issue:10

    Topics: 3-Hydroxybutyric Acid; Abomasum; Animals; Calcium; Cattle; Cattle Diseases; Endometritis; Fatty Acid

2012
Acute-phase protein concentration and metabolic status affect the outcome of treatment in cows with clinical and subclinical endometritis.
    The Veterinary record, 2012, Sep-01, Volume: 171, Issue:9

    Topics: 3-Hydroxybutyric Acid; Acute-Phase Proteins; Animals; Cattle; Cattle Diseases; Endometritis; Female;

2012
Clinical endometritis in an Argentinean herd of dairy cows: risk factors and reproductive efficiency.
    Journal of dairy science, 2013, Volume: 96, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Argentina; Blood Urea Nitrogen; Cattle; Cattle Diseases; Endometriti

2013
Direct-fed microbial supplementation on ruminal digestion, health, and performance of pre- and postpartum dairy cattle.
    Journal of dairy science, 2006, Volume: 89, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cattle; Cattle Diseases; Diet; Digestion; Endometriti

2006
Neutrophil function and energy status in Holstein cows with uterine health disorders.
    Veterinary immunology and immunopathology, 2006, Sep-15, Volume: 113, Issue:1-2

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Endometritis; Energy Metabolism; Fatty Acid

2006