3-hydroxybutyric acid has been researched along with Diabetic Nephropathies in 12 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Diabetic Nephropathies: KIDNEY injuries associated with diabetes mellitus and affecting KIDNEY GLOMERULUS; ARTERIOLES; KIDNEY TUBULES; and the interstitium. Clinical signs include persistent PROTEINURIA, from microalbuminuria progressing to ALBUMINURIA of greater than 300 mg/24 h, leading to reduced GLOMERULAR FILTRATION RATE and END-STAGE RENAL DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the relationship between leptin levels and IDDM with and without microalbuminuria, fasting serum levels of leptin, insulin, insulin-like growth factor-1 (IGF-1), sex hormone-binding globulin (SHBG), testosterone (SHBG) ratio, blood pressure and body mass index (BMI) were measured in 18 normo- and 11 microalbuminuric females with >5 years of IDDM, and 24 healthy controls in late puberty." | 7.70 | Serum leptin levels in young females with insulin-dependent diabetes and the relationship to hyperandrogenicity and microalbuminuria. ( Persson, B; Rudberg, S, 1998) |
| "To investigate the relationship between leptin levels and IDDM with and without microalbuminuria, fasting serum levels of leptin, insulin, insulin-like growth factor-1 (IGF-1), sex hormone-binding globulin (SHBG), testosterone (SHBG) ratio, blood pressure and body mass index (BMI) were measured in 18 normo- and 11 microalbuminuric females with >5 years of IDDM, and 24 healthy controls in late puberty." | 3.70 | Serum leptin levels in young females with insulin-dependent diabetes and the relationship to hyperandrogenicity and microalbuminuria. ( Persson, B; Rudberg, S, 1998) |
| "Early diagnosis of diabetic nephropathy (DN) is difficult although it is of crucial importance to prevent its development." | 1.39 | GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy. ( Aa, J; Cao, B; Ge, Y; Li, M; Liu, L; Liu, Z; Qin, W; Shi, J; Wang, G; Wang, X; Yu, X; Zha, W; Zhao, C; Zheng, T, 2013) |
| "Compared with nondiabetic subjects, IDDM with or without CDAN exhibited reduced epinephrine (P = 0." | 1.29 | Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia. ( Craft, S; Cryer, PE; Dagogo-Jack, SE, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 3 (25.00) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Liu, Y | 1 |
| Wang, J | 1 |
| Xu, F | 1 |
| Zhang, S | 1 |
| Cui, S | 1 |
| Li, Y | 1 |
| Wang, X | 3 |
| Zheng, H | 1 |
| Li, J | 2 |
| Kong, Y | 1 |
| Yang, J | 2 |
| Jiang, X | 1 |
| Chang, B | 1 |
| Wan, SR | 1 |
| Teng, FY | 1 |
| Fan, W | 1 |
| Xu, BT | 1 |
| Li, XY | 1 |
| Tan, XZ | 1 |
| Guo, M | 1 |
| Gao, CL | 1 |
| Zhang, CX | 1 |
| Jiang, ZZ | 1 |
| Xu, Y | 1 |
| Fang, Y | 1 |
| Chen, B | 1 |
| Gong, AY | 1 |
| Malhotra, DK | 1 |
| Gupta, R | 1 |
| Dworkin, LD | 1 |
| Gong, R | 1 |
| Li, M | 1 |
| Aa, J | 1 |
| Qin, W | 1 |
| Zha, W | 1 |
| Ge, Y | 1 |
| Liu, L | 1 |
| Zheng, T | 1 |
| Cao, B | 1 |
| Shi, J | 1 |
| Zhao, C | 1 |
| Yu, X | 1 |
| Wang, G | 1 |
| Liu, Z | 1 |
| Zhang, D | 1 |
| Yang, H | 1 |
| Kong, X | 1 |
| Wang, K | 1 |
| Mao, X | 1 |
| Yan, X | 1 |
| Wang, Y | 1 |
| Liu, S | 1 |
| Zhang, X | 1 |
| Chen, L | 1 |
| Wu, J | 1 |
| Wei, M | 1 |
| Guan, Y | 1 |
| Hayashi, T | 1 |
| Ago, K | 1 |
| Ago, M | 1 |
| Ogata, M | 1 |
| Matta, MP | 1 |
| Melki, V | 1 |
| Bessière-Lacombe, S | 1 |
| Hanaire-Broutin, H | 1 |
| Dagogo-Jack, SE | 1 |
| Craft, S | 1 |
| Cryer, PE | 1 |
| Jiffri, E | 1 |
| Broom, J | 1 |
| Whiting, PH | 1 |
| Rudberg, S | 1 |
| Persson, B | 1 |
| Luzi, L | 1 |
| Battezzati, A | 1 |
| Perseghin, G | 1 |
| Bianchi, E | 1 |
| Vergani, S | 1 |
| Secchi, A | 1 |
| La Rocca, E | 1 |
| Staudacher, C | 1 |
| Spotti, D | 1 |
| Ferrari, G | 1 |
| Ostman, J | 1 |
| Bolinder, J | 1 |
| Gunnarsson, R | 1 |
| Brattström, C | 1 |
| Tydén, G | 1 |
| Wahren, J | 1 |
| Groth, CG | 1 |
12 other studies available for 3-hydroxybutyric acid and Diabetic Nephropathies
| Article | Year |
|---|---|
A J-shaped relationship between ketones and the risk of diabetic kidney disease in patients with type 2 diabetes: New insights from a cross-sectional study.
Topics: 3-Hydroxybutyric Acid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; H | 2023 |
BDH1-mediated βOHB metabolism ameliorates diabetic kidney disease by activation of NRF2-mediated antioxidative pathway.
Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Diabetes Mellitus; Diabetic Nephropathies; Humans; Kid | 2023 |
The ketone body β-hydroxybutyrate mitigates the senescence response of glomerular podocytes to diabetic insults.
Topics: 3-Hydroxybutyric Acid; Albuminuria; Animals; Diabetes Mellitus; Diabetic Nephropathies; Glycogen Syn | 2021 |
GC/TOFMS analysis of metabolites in serum and urine reveals metabolic perturbation of TCA cycle in db/db mice involved in diabetic nephropathy.
Topics: 3-Hydroxybutyric Acid; Albuminuria; Allantoin; Amino Acids; Animals; Arachidonic Acid; Biomarkers; C | 2013 |
Proteomics analysis reveals diabetic kidney as a ketogenic organ in type 2 diabetes.
Topics: 3-Hydroxybutyric Acid; Animals; Blotting, Western; Cells, Cultured; Collagen Type I; Diabetes Mellit | 2011 |
Positional asphyxia or diabetic ketoacidosis? A case report.
Topics: 3-Hydroxybutyric Acid; Acetone; Aged; Asphyxia; Diabetic Ketoacidosis; Diabetic Nephropathies; Femal | 2011 |
What are capillary blood ketone levels in type 1 diabetic patients using CSII in normal conditions of insulin delivery?
Topics: 3-Hydroxybutyric Acid; Blood Glucose Self-Monitoring; Body Mass Index; Capillaries; Diabetes Mellitu | 2004 |
Hypoglycemia-associated autonomic failure in insulin-dependent diabetes mellitus. Recent antecedent hypoglycemia reduces autonomic responses to, symptoms of, and defense against subsequent hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Blood Pressure; Cognition; Diabetes Mellitus, Type 1; D | 1993 |
Altered renal intermediary metabolism and the onset of renal dysfunction in the streptozotocin diabetic rat.
Topics: 3-Hydroxybutyric Acid; Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; | 1996 |
Serum leptin levels in young females with insulin-dependent diabetes and the relationship to hyperandrogenicity and microalbuminuria.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Albuminuria; Blood Pressure; Body Mass Index; Chromatograp | 1998 |
Lack of feedback inhibition of insulin secretion in denervated human pancreas.
Topics: 3-Hydroxybutyric Acid; Adult; Analysis of Variance; Blood Glucose; C-Peptide; Denervation; Diabetes | 1992 |
Effects of pancreas transplantation on metabolic and hormonal profiles in IDDM patients.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Circadian Rhythm; Creatinine; Diabetes Mellitus, Type 1 | 1989 |