3-hydroxybutyric acid has been researched along with Diabetes, Gestational in 10 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Diabetes, Gestational: Diabetes mellitus induced by PREGNANCY but resolved at the end of pregnancy. It does not include previously diagnosed diabetics who become pregnant (PREGNANCY IN DIABETICS). Gestational diabetes usually develops in late pregnancy when insulin antagonistic hormones peaks leading to INSULIN RESISTANCE; GLUCOSE INTOLERANCE; and HYPERGLYCEMIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Previous studies have underlined the importance of the carnitine shuttle system and its dysfunction both in normal pregnancy and in type 1 and 2 diabetes." | 3.73 | Gestational diabetes exhibits lack of carnitine deficiency despite relatively low carnitine levels and alterations in ketogenesis. ( Anagnou, NP; Anogianaki, N; Bikouvarakis, S; Evangeliou, A; Koumantakis, E; Maropoulos, G; Pappa, KI; Salamalekis, E, 2005) |
| "Among women with dietarily treated gestational diabetes the glucose concentrations were significantly higher from 3 to 9 hours after an evening meal, whereas suppression of free fatty acids and beta-hydroxybutyrate was less sustained after a morning feeding." | 2.69 | When is fasting really fasting? The influence of time of day, interval after a meal, and maternal body mass on maternal glycemia in gestational diabetes. ( Buchanan, TA; Chen, W; Sacks, DA; Wolde-Tsadik, G, 1999) |
| "However, their association with gestational diabetes mellitus (GDM) is largely unknown." | 1.40 | Early pregnancy urinary biomarkers of fatty acid and carbohydrate metabolism in pregnancies complicated by gestational diabetes. ( Bralley, JA; David, RM; Enquobahrie, DA; Fernandez, MA; Frederick, IO; Qiu, C; Sorensen, TK; Williams, MA, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dudzik, D | 1 |
| Zorawski, M | 1 |
| Skotnicki, M | 1 |
| Zarzycki, W | 1 |
| García, A | 1 |
| Angulo, S | 1 |
| Lorenzo, MP | 1 |
| Barbas, C | 1 |
| Ramos, MP | 1 |
| Qiu, C | 1 |
| Enquobahrie, DA | 1 |
| Frederick, IO | 1 |
| Sorensen, TK | 1 |
| Fernandez, MA | 1 |
| David, RM | 1 |
| Bralley, JA | 1 |
| Williams, MA | 1 |
| Mohammed, OJ | 1 |
| Latif, ML | 1 |
| Pratten, MK | 1 |
| Tisi, DK | 1 |
| Burns, DH | 1 |
| Luskey, GW | 1 |
| Koski, KG | 1 |
| Pappa, KI | 1 |
| Anagnou, NP | 1 |
| Salamalekis, E | 1 |
| Bikouvarakis, S | 1 |
| Maropoulos, G | 1 |
| Anogianaki, N | 1 |
| Evangeliou, A | 1 |
| Koumantakis, E | 1 |
| Nord, E | 1 |
| Hanson, U | 1 |
| Persson, B | 1 |
| Sacks, DA | 1 |
| Chen, W | 1 |
| Wolde-Tsadik, G | 1 |
| Buchanan, TA | 1 |
| Homko, C | 1 |
| Sivan, E | 1 |
| Chen, X | 1 |
| Reece, EA | 1 |
| Boden, G | 1 |
| Rae, A | 1 |
| Bond, D | 1 |
| Evans, S | 1 |
| North, F | 1 |
| Roberman, B | 1 |
| Walters, B | 1 |
| Montelongo, A | 1 |
| Lasunción, MA | 1 |
| Pallardo, LF | 1 |
| Herrera, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Early Screening and Intervention for Gestational Diabetes Mellitus on Pregnancy Outcomes: the TESGO Randomized Trial[NCT03523143] | 967 participants (Actual) | Interventional | 2018-06-11 | Active, not recruiting | |||
| The Maternal-fetal Gradient of Free and Esterified Phytosterols in Term Human Pregnancy at Delivery[NCT03705767] | 68 participants (Actual) | Observational | 2016-10-26 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for 3-hydroxybutyric acid and Diabetes, Gestational
| Article | Year |
|---|---|
When is fasting really fasting? The influence of time of day, interval after a meal, and maternal body mass on maternal glycemia in gestational diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Body Mass Index; Diabetes, Gestational; Fasting; Fatty | 1999 |
A randomised controlled trial of dietary energy restriction in the management of obese women with gestational diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Birth Weight; Blood Glucose; Diabetes, Gestational; Diet, Reducing; En | 2000 |
8 other studies available for 3-hydroxybutyric acid and Diabetes, Gestational
| Article | Year |
|---|---|
GC-MS based Gestational Diabetes Mellitus longitudinal study: Identification of 2-and 3-hydroxybutyrate as potential prognostic biomarkers.
Topics: 3-Hydroxybutyric Acid; Biomarkers; Diabetes, Gestational; Female; Gas Chromatography-Mass Spectromet | 2017 |
Early pregnancy urinary biomarkers of fatty acid and carbohydrate metabolism in pregnancies complicated by gestational diabetes.
Topics: 3-Hydroxybutyric Acid; Adult; Biomarkers; Diabetes, Gestational; Fatty Acids; Female; Humans; Lactic | 2014 |
Diabetes-induced effects on cardiomyocytes in chick embryonic heart micromass and mouse embryonic D3 differentiated stem cells.
Topics: 3-Hydroxybutyric Acid; Animals; Cell Movement; Cells, Cultured; Chick Embryo; Diabetes Complications | 2017 |
Fetal exposure to altered amniotic fluid glucose, insulin, and insulin-like growth factor-binding protein 1 occurs before screening for gestational diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Amniotic Fluid; Diabetes, Gestational; Female; Glucose; Humans; Insuli | 2011 |
Gestational diabetes exhibits lack of carnitine deficiency despite relatively low carnitine levels and alterations in ketogenesis.
Topics: 3-Hydroxybutyric Acid; Adult; Body Mass Index; Body Weight; Carnitine; Case-Control Studies; Diabete | 2005 |
Assessment of therapy in gestational diabetes by substrate and hormone responses to a standardized test meal.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Amino Acids; Blood Glucose; Body Mass Index; C-Peptide; Di | 1997 |
Insulin secretion during and after pregnancy in patients with gestational diabetes mellitus.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; C-Peptide; Diabetes, Gestational; Female; Glucose Toler | 2001 |
Longitudinal study of plasma lipoproteins and hormones during pregnancy in normal and diabetic women.
Topics: 3-Hydroxybutyric Acid; Adult; Analysis of Variance; Apolipoproteins; Body Mass Index; Cholesterol; D | 1992 |