Page last updated: 2024-10-17

3-hydroxybutyric acid and Delayed Effects, Prenatal Exposure

3-hydroxybutyric acid has been researched along with Delayed Effects, Prenatal Exposure in 8 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Research Excerpts

ExcerptRelevanceReference
" Particularly, anserine abundance, lowered by maternal obesity, was normalized by a preconceptional weight loss, whatever the post-weaning diet."3.96Differential Effects of Post-Weaning Diet and Maternal Obesity on Mouse Liver and Brain Metabolomes. ( Baly, C; Gabory, A; Jammes, H; Jouin, M; Jouneau, L; Rousseau-Ralliard, D; Safi-Stibler, S; Seyer, A; Thévenot, EA, 2020)
"Lysine was higher in female offspring, while 3-hydroxybutyric acid and acetic acid were significantly higher in male offspring."1.62Sex-Specific Differences in Lysine, 3-Hydroxybutyric Acid and Acetic Acid in Offspring Exposed to Maternal and Postnatal High Linoleic Acid Diet, Independent of Diet. ( Cuffe, JSM; Holland, OJ; Hryciw, DH; McAinch, AJ; McKeating, DR; Melvin, SD; Perkins, AV; Shrestha, N, 2021)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19901 (12.50)18.7374
1990's2 (25.00)18.2507
2000's0 (0.00)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Shrestha, N1
Melvin, SD1
McKeating, DR1
Holland, OJ1
Cuffe, JSM1
Perkins, AV1
McAinch, AJ1
Hryciw, DH1
Safi-Stibler, S1
Thévenot, EA1
Jouneau, L1
Jouin, M1
Seyer, A1
Jammes, H1
Rousseau-Ralliard, D1
Baly, C1
Gabory, A1
Lowe, WL1
Bain, JR1
Nodzenski, M1
Reisetter, AC1
Muehlbauer, MJ1
Stevens, RD1
Ilkayeva, OR1
Lowe, LP1
Metzger, BE1
Newgard, CB1
Scholtens, DM1
Harris, DL1
Weston, PJ1
Harding, JE1
Langley-Evans, SC1
Daniel, ZC1
Wells, CA1
Ryan, KJ1
Plant, R1
Welham, SJ1
Almeida, A1
González-Buitrago, JM1
Bolaños, JP1
Medina, JM1
Clarke, L1
Andrews, DC1
Lomax, MA1
Symonds, ME1
Menon, NK1
Lopez, RR1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Phase 2 Open Label Randomized Controlled Trial Determir Vs Neutral Protamine Hagedorn (NPH) In Pregnant Women: DETERMINE Study[NCT05124457]Phase 2336 participants (Anticipated)Interventional2022-02-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for 3-hydroxybutyric acid and Delayed Effects, Prenatal Exposure

ArticleYear
Lactate, rather than ketones, may provide alternative cerebral fuel in hypoglycaemic newborns.
    Archives of disease in childhood. Fetal and neonatal edition, 2015, Volume: 100, Issue:2

    Topics: 3-Hydroxybutyric Acid; Biomarkers; Birth Weight; Blood Glucose; Breast Feeding; Double-Blind Method;

2015

Other Studies

7 other studies available for 3-hydroxybutyric acid and Delayed Effects, Prenatal Exposure

ArticleYear
Sex-Specific Differences in Lysine, 3-Hydroxybutyric Acid and Acetic Acid in Offspring Exposed to Maternal and Postnatal High Linoleic Acid Diet, Independent of Diet.
    International journal of molecular sciences, 2021, Sep-23, Volume: 22, Issue:19

    Topics: 3-Hydroxybutyric Acid; Acetic Acid; Adult Children; Animals; Animals, Newborn; Diet; Diet, High-Fat;

2021
Differential Effects of Post-Weaning Diet and Maternal Obesity on Mouse Liver and Brain Metabolomes.
    Nutrients, 2020, May-28, Volume: 12, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Anserine; Brain; Deoxyglucose; Diet; Energy Metabolism; Female; Home

2020
Maternal BMI and Glycemia Impact the Fetal Metabolome.
    Diabetes care, 2017, Volume: 40, Issue:7

    Topics: 3-Hydroxybutyric Acid; Adiposity; Adult; Amino Acids, Branched-Chain; Birth Weight; Blood Glucose; B

2017
Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: role of fetal exposure to {beta}-hydroxybutyrate.
    Experimental physiology, 2011, Volume: 96, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Dietary Proteins; Female; Fetal Growth Retardation; Hydroxymethylglu

2011
Fuel utilization by early newborn brain is preserved under congenital hypothyroidism in the rat.
    Pediatric research, 1996, Volume: 40, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Antithyroid Agents; Brain; Congenital Hypothyroidi

1996
Effect of maternal glucose infusion on brown adipose tissue and liver development in the neonatal lamb.
    Reproduction, fertility, and development, 1996, Volume: 8, Issue:7

    Topics: 3-Hydroxybutyric Acid; Adipose Tissue, Brown; Animals; Animals, Newborn; Blood Glucose; Fatty Acids,

1996
The effects of mild congenital methylmercury intoxication on the metabolism of 3-hydroxybutyrate and glucose in the brains of suckling rats.
    Neurotoxicology, 1985,Spring, Volume: 6, Issue:1

    Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Suckling; Body Weight; Brain; Female; Glucose; Hydro

1985