Page last updated: 2024-10-17

3-hydroxybutyric acid and Cryopyrin-Associated Periodic Syndromes

3-hydroxybutyric acid has been researched along with Cryopyrin-Associated Periodic Syndromes in 4 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Cryopyrin-Associated Periodic Syndromes: A group of rare autosomal dominant diseases, commonly characterized by atypical URTICARIA (hives) with systemic symptoms that develop into end-organ damage. The atypical hives do not involve T-cell or autoantibody. Cryopyrin-associated periodic syndrome includes three previously distinct disorders: Familial cold autoinflammatory syndrome; Muckle-Wells Syndrome; and CINCA Syndrome, that are now considered to represent a disease continuum, all caused by NLRP3 PROTEIN mutations.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Youm, YH1
Nguyen, KY1
Grant, RW1
Goldberg, EL1
Bodogai, M1
Kim, D1
D'Agostino, D1
Planavsky, N1
Lupfer, C1
Kanneganti, TD1
Kang, S1
Horvath, TL1
Fahmy, TM1
Crawford, PA1
Biragyn, A1
Alnemri, E1
Dixit, VD1
Kugelberg, E1
Netea, MG1
Joosten, LA1
Groß, CJ1
Groß, O1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Keto-diet for Intubated Critical Care COVID-19 (KICC-COVID19)[NCT04358835]0 participants (Actual)Interventional2020-09-01Withdrawn (stopped due to Study did not begin enrollment, multiple competing studies at same institution)
COVID-19 Vaccination in Subjects With Obesity: Impact of Metabolic Health and the Role of a Ketogenic Diet[NCT05163743]24 participants (Anticipated)Interventional2021-05-23Recruiting
A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma[NCT05119010]60 participants (Anticipated)Interventional2023-03-24Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for 3-hydroxybutyric acid and Cryopyrin-Associated Periodic Syndromes

ArticleYear
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Nature medicine, 2015, Volume: 21, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Aged; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Perio

2015
Inflammasome: starving inflammation.
    Nature reviews. Immunology, 2015, Volume: 15, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Periodic Syndromes

2015
Inflammasome inhibition: putting out the fire.
    Cell metabolism, 2015, Apr-07, Volume: 21, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Periodic Syndromes

2015
The Nlrp3 inflammasome admits defeat.
    Trends in immunology, 2015, Volume: 36, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Caspase 1; Cryopyrin-Associated Periodic Syndromes

2015