3-hydroxybutyric acid has been researched along with Convulsive Generalized Seizure Disorder in 3 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Twenty children with intractable Lennox-Gastaut syndrome (LGS) were fasted 36 h and then randomized to receive the classic KD in conjunction with a solution containing either 60 g/day of glucose or saccharin." | 5.14 | A blinded, crossover study of the efficacy of the ketogenic diet. ( Freeman, JM; Goodman, SN; Kossoff, EH; Pyzik, PL; Vining, EP; Ye, X, 2009) |
| "We evaluated the ability of the ketogenic diet (KD) to improve thresholds to flurothyl-induced seizures in two mouse lines with Scn1a mutations: one that models Dravet syndrome (DS) and another that models genetic (generalized) epilepsy with febrile seizures plus (GEFS+)." | 3.77 | Protective effect of the ketogenic diet in Scn1a mutant mice. ( Borges, K; Catterall, WA; Dutton, SB; Escayg, A; Jumbo-Lucioni, P; Kalume, F; Sawyer, NT, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Freeman, JM | 1 |
| Vining, EP | 1 |
| Kossoff, EH | 1 |
| Pyzik, PL | 1 |
| Ye, X | 1 |
| Goodman, SN | 1 |
| Spulber, G | 1 |
| Spulber, S | 1 |
| Hagenäs, L | 1 |
| Amark, P | 1 |
| Dahlin, M | 1 |
| Dutton, SB | 1 |
| Sawyer, NT | 1 |
| Kalume, F | 1 |
| Jumbo-Lucioni, P | 1 |
| Borges, K | 1 |
| Catterall, WA | 1 |
| Escayg, A | 1 |
1 trial available for 3-hydroxybutyric acid and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
A blinded, crossover study of the efficacy of the ketogenic diet.
Topics: 3-Hydroxybutyric Acid; Child; Child, Preschool; Cross-Over Studies; Diet, Ketogenic; Double-Blind Me | 2009 |
2 other studies available for 3-hydroxybutyric acid and Convulsive Generalized Seizure Disorder
| Article | Year |
|---|---|
Growth dependence on insulin-like growth factor-1 during the ketogenic diet.
Topics: 3-Hydroxybutyric Acid; Anticonvulsants; Body Height; Body Mass Index; Child; Child, Preschool; Diet, | 2009 |
Protective effect of the ketogenic diet in Scn1a mutant mice.
Topics: 3-Hydroxybutyric Acid; Animals; Convulsants; Diet, Ketogenic; Disease Models, Animal; Dose-Response | 2011 |