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3-hydroxybutyric acid and Complications, Pregnancy

3-hydroxybutyric acid has been researched along with Complications, Pregnancy in 29 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Research Excerpts

ExcerptRelevanceReference
" On day 140 of pregnancy the ewes were sampled for determination of betaOH-butyrate (BHB), AST, glucose, non-esterified fatty acids (NEFA), total cholesterol (TCH), insulin, T4, T3, cortisol, IGF-1 and leptin."3.73Endocrine characteristics of late pregnant hyperketonaemic ewes and their reproductive performance following the induction of ovarian cyclicity out of the breeding season. ( Cernescu, H; Chilliard, Y; Cseh, S; Dankó, G; Delavaud, C; Gáspárdy, A; Huszenicza, G; Kulcsár, M; Mircu, C; Nikolic, AJ; Rudas, P, 2006)
"Urea and BCS were not significantly associated with LDA in any of the weeks examined."2.69The association between selected metabolic parameters and left abomasal displacement in dairy cows. ( Duffield, T; Edge, V; Geishauser, T; Leslie, K; Sandals, D, 1998)
"Pregnancy was diagnosed on d 31 and 59 of presumptive gestation."1.56Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer. ( Bromfield, JJ; Edelhoff, INF; Pereira, MHC; Santos, JEP; Vasconcelos, JLM, 2020)
"Fetal ketoacidosis with hypoxic-ischemic brain damage was determined to be the cause of death."1.48Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis. ( Fliss, B; Gascho, D; Heimer, J; Martinez, RM; Zoelch, N, 2018)
"However, their association with gestational diabetes mellitus (GDM) is largely unknown."1.40Early pregnancy urinary biomarkers of fatty acid and carbohydrate metabolism in pregnancies complicated by gestational diabetes. ( Bralley, JA; David, RM; Enquobahrie, DA; Fernandez, MA; Frederick, IO; Qiu, C; Sorensen, TK; Williams, MA, 2014)
"Furthermore, the occurrence of fasting hypoglycemia necessitates careful monitoring of postnatal blood glucose values."1.27Intrauterine growth and postnatal fasting metabolism in infants of obese mothers. ( Dunnington, R; Gross, T; Kliegman, R; Morton, S, 1984)
"On the day of tetany, the mean plasma Ca of the cows with tetany was 4."1.27Wheat pasture poisoning. II. Tissue composition of cattle grazing cereal forages and related to tetany. ( Bohman, VR; Griffin, D; Horn, FP; Hurst, JG; Littledike, ET, 1983)
"Systemic ketosis was induced in first-parity gilts by the isocaloric substitution of glucose with 1,3-butylene glycol to supply 20% of the total dietary energy beginning on d 23 (23 BG) or d 60 (60 BG) of gestation."1.27Fetal hepatic and neural substrate utilization as affected by induced nutritional ketosis in swine. ( McMurtry, JP; Rosebrough, RW; Steele, NC, 1984)
"Maternal lipemia (L), one of the consequences of poorly controlled diabetes in gestation, was induced in pregnant rats by feedings of a diet containing 45% fat."1.27Fetal glycerol metabolism in experimental maternal lipemia. ( Stiel, L; Wapnir, RA, 1985)
"Maternal ketosis was induced in sows by feeding 20% of the dietary energy as 1,3-butylene glycol (BG), medium-chain triglycerides (MCT), or a combination of the two."1.26Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver. ( Frobish, LT; Rosebrough, RW; Steele, NC, 1981)

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199011 (37.93)18.7374
1990's4 (13.79)18.2507
2000's2 (6.90)29.6817
2010's9 (31.03)24.3611
2020's3 (10.34)2.80

Authors

AuthorsStudies
Pascottini, OB1
Carvalho, MR1
Van Schyndel, SJ1
Ticiani, E1
Spricigo, JW1
Mamedova, LK1
Ribeiro, ES1
LeBlanc, SJ1
Xue, Y1
Guo, C1
Hu, F1
Zhu, W1
Mao, S1
Edelhoff, INF1
Pereira, MHC1
Bromfield, JJ1
Vasconcelos, JLM1
Santos, JEP1
Creutzinger, KC1
Dann, HM1
Moraes, LE1
Krawczel, PD1
Proudfoot, KL1
Polizel, DM1
Susin, I1
Gentil, RS1
Ferreira, EM1
de Souza, RA1
Freire, AP1
Pires, AV1
Ferraz, MV1
Rodrigues, PH1
Eastridge, ML1
Hill, SL1
Olson, KC1
Jaeger, JR1
Stevenson, JS1
Heimer, J1
Gascho, D1
Fliss, B1
Martinez, RM1
Zoelch, N1
Scholtens, DM1
Muehlbauer, MJ1
Daya, NR1
Stevens, RD1
Dyer, AR1
Lowe, LP1
Metzger, BE1
Newgard, CB1
Bain, JR1
Lowe, WL1
Qiu, C1
Enquobahrie, DA1
Frederick, IO1
Sorensen, TK1
Fernandez, MA1
David, RM1
Bralley, JA1
Williams, MA1
Doré, V1
Dubuc, J1
Bélanger, AM1
Buczinski, S1
Ghanem, MM1
El-Deeb, WM1
Langley-Evans, SC1
Daniel, ZC1
Wells, CA1
Ryan, KJ1
Plant, R1
Welham, SJ1
Kulcsár, M1
Dankó, G1
Delavaud, C1
Mircu, C1
Nikolic, AJ1
Gáspárdy, A1
Cernescu, H1
Chilliard, Y1
Cseh, S1
Rudas, P1
Huszenicza, G1
Kliegman, R1
Gross, T1
Morton, S1
Dunnington, R1
Prentice, AM1
Prentice, A1
Lamb, WH1
Lunn, PG1
Austin, S1
Bohman, VR1
Horn, FP1
Littledike, ET1
Hurst, JG1
Griffin, D1
Shambaugh, GE1
Angulo, MC1
Koehler, RR1
Steele, NC2
Rosebrough, RW2
McMurtry, JP1
Frobish, LT1
Sparks, JW1
Pegorier, JP1
Girard, J1
Battaglia, FC1
Studer, VA1
Grummer, RR1
Bertics, SJ1
Reynolds, CK1
Geishauser, T1
Leslie, K1
Duffield, T1
Sandals, D1
Edge, V1
Tornquist, SJ1
Van Saun, RJ1
Smith, BB1
Cebra, CK1
Snyder, SP1
Ivany, JM1
Anderson, DE1
Styrud, J1
Eriksson, UJ1
Roca, P1
Gianotti, M1
Palou, A1
Testar, X1
Llobera, M1
Herrera, E1
Wapnir, RA1
Stiel, L1
Chandler, KD1
Leury, BJ1
Bird, AR1
Bell, AW1

Trials

3 trials available for 3-hydroxybutyric acid and Complications, Pregnancy

ArticleYear
Feed restriction to induce and meloxicam to mitigate potential systemic inflammation in dairy cows before calving.
    Journal of dairy science, 2019, Volume: 102, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animal Feed; Animals; Anti-Inflammatory Agents, Non-Steroidal; Body Weight; C

2019
Effects of prepartum stocking density and a blind on physiological biomarkers, health, and hygiene of transition Holstein dairy cows.
    Journal of dairy science, 2021, Volume: 104, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Biomarkers; Cattle; Cattle Diseases; Dairying; Fatty Acids, Nonester

2021
The association between selected metabolic parameters and left abomasal displacement in dairy cows.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1998, Volume: 45, Issue:8

    Topics: 3-Hydroxybutyric Acid; Abomasum; Animals; Aspartate Aminotransferases; Blood Glucose; Calcium; Cattl

1998

Other Studies

26 other studies available for 3-hydroxybutyric acid and Complications, Pregnancy

ArticleYear
Undernutrition-induced lipid metabolism disorder triggers oxidative stress in maternal and fetal livers using a model of pregnant sheep.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020, Volume: 34, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Fatty Acids, Nonesterified; Female; Fetus; Hepatocytes

2020
Inflammatory diseases in dairy cows: Risk factors and associations with pregnancy after embryo transfer.
    Journal of dairy science, 2020, Volume: 103, Issue:12

    Topics: 3-Hydroxybutyric Acid; Animals; Cattle; Cattle Diseases; Embryo Transfer; Endometritis; Female; Fert

2020
Crude glycerin decreases nonesterified fatty acid concentration in ewes during late gestation and early lactation.
    Journal of animal science, 2017, Volume: 95, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet; Fatty

2017
Serum and plasma metabolites associated with postpartum ovulation and pregnancy risks in suckled beef cows subjected to artificial insemination.
    Journal of animal science, 2018, Feb-15, Volume: 96, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Composition; Cattle; Estrous Cycle; Female; Inse

2018
Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis.
    Journal of forensic and legal medicine, 2018, Volume: 59

    Topics: 3-Hydroxybutyric Acid; Acetone; Acidosis, Lactic; Alcoholism; Cerebrum; Fasting; Female; Fetal Blood

2018
Metabolomics reveals broad-scale metabolic perturbations in hyperglycemic mothers during pregnancy.
    Diabetes care, 2014, Volume: 37, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adult; Amino Acids; Blood Glucose; C-Peptide; Female; Food; Glucose Tolerance

2014
Early pregnancy urinary biomarkers of fatty acid and carbohydrate metabolism in pregnancies complicated by gestational diabetes.
    Diabetes research and clinical practice, 2014, Volume: 104, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adult; Biomarkers; Diabetes, Gestational; Fatty Acids; Female; Humans; Lactic

2014
Definition of prepartum hyperketonemia in dairy goats.
    Journal of dairy science, 2015, Volume: 98, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Canada; Cattle; Cohort Studies; Female; Goat Diseases; Goats; Ketosi

2015
Lecithin cholesterol acyltransferase (LCAT) activity as a predictor for ketosis and parturient haemoglobinuria in Egyptian water buffaloes.
    Research in veterinary science, 2010, Volume: 88, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blood Proteins; Buffaloes; Cholesterol; Fatty Acids,

2010
Protein restriction in the pregnant mouse modifies fetal growth and pulmonary development: role of fetal exposure to {beta}-hydroxybutyrate.
    Experimental physiology, 2011, Volume: 96, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Dietary Proteins; Female; Fetal Growth Retardation; Hydroxymethylglu

2011
Endocrine characteristics of late pregnant hyperketonaemic ewes and their reproductive performance following the induction of ovarian cyclicity out of the breeding season.
    Acta veterinaria Hungarica, 2006, Volume: 54, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Fatty Acids, Nonesterified; Female; Gona

2006
Intrauterine growth and postnatal fasting metabolism in infants of obese mothers.
    The Journal of pediatrics, 1984, Volume: 104, Issue:4

    Topics: 3-Hydroxybutyric Acid; Birth Weight; Blood Glucose; Body Weight; Fasting; Fatty Acids, Nonesterified

1984
Metabolic consequences of fasting during Ramadan in pregnant and lactating women.
    Human nutrition. Clinical nutrition, 1983, Volume: 37, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adult; Africa, Western; Alanine; Blood Glucose; Energy Metabolism; Fasting; F

1983
Wheat pasture poisoning. II. Tissue composition of cattle grazing cereal forages and related to tetany.
    Journal of animal science, 1983, Volume: 57, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Calcitriol; Calcium; Cattle; Cattle Diseases; Female;

1983
Fetal fuels. VII. Ketone bodies inhibit synthesis of purines in fetal rat brain.
    The American journal of physiology, 1984, Volume: 247, Issue:1 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenine; Animals; Brain; Carbon Radioisotopes; Cycloheximide;

1984
Fetal hepatic and neural substrate utilization as affected by induced nutritional ketosis in swine.
    Journal of animal science, 1984, Volume: 58, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetates; Acidosis; Animal Feed; Animals; Brain; Butylene Glycols; Fatty Acid

1984
Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver.
    Growth, 1981,Spring, Volume: 45, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Body Composition; Brain; Butylene Glycols; Dietary Carbohy

1981
Substrate concentration changes during pregnancy in the guinea pig studied under unstressed steady state conditions.
    Pediatric research, 1981, Volume: 15, Issue:10

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Body Weight; Fatty Acids, Nonesterifie

1981
Effect of prepartum propylene glycol administration on periparturient fatty liver in dairy cows.
    Journal of dairy science, 1993, Volume: 76, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cattle; Cattle Diseases; Fatty Acids, Nonesterified;

1993
Hepatic lipidosis in llamas and alpacas: 31 cases (1991-1997).
    Journal of the American Veterinary Medical Association, 1999, May-01, Volume: 214, Issue:9

    Topics: 3-Hydroxybutyric Acid; Animals; Anorexia; Aspartate Aminotransferases; Bile Acids and Salts; Camelid

1999
Propylene glycol toxicosis in a llama.
    Journal of the American Veterinary Medical Association, 2001, Jan-15, Volume: 218, Issue:2

    Topics: 3-Hydroxybutyric Acid; Abdomen; Animals; Anti-Ulcer Agents; Aspartate Aminotransferases; Camelids, N

2001
Effects of D-glucose and beta-hydroxybutyric acid on the in vitro development of (pre)chondrocytes from embryos of normal and diabetic rats.
    Acta endocrinologica, 1990, Volume: 122, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Cartilage; Cell Differentiation; Cell Division; Cells, Cultured; Den

1990
Metabolic response to short term starvation in non-pregnant and late pregnant cafeteria-obese rats.
    Archives internationales de physiologie et de biochimie, 1989, Volume: 97, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Female; Fetal Blood; Glycerol; Hydroxy

1989
Comparative metabolic effects of chronic ethanol intake and undernutrition in pregnant rats and their fetuses.
    Alcoholism, clinical and experimental research, 1988, Volume: 12, Issue:2

    Topics: 3-Hydroxybutyric Acid; Alcoholism; Animals; Blood Proteins; Body Weight; Female; Fetal Alcohol Spect

1988
Fetal glycerol metabolism in experimental maternal lipemia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1985, Volume: 178, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Dietary Fats; Fatty Acids, Nonesterified; Female; Fetus; Glycerol; G

1985
Effects of undernutrition and exercise during late pregnancy on uterine, fetal and uteroplacental metabolism in the ewe.
    The British journal of nutrition, 1985, Volume: 53, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Fatty Acids, Nonesterified; Female; Fetus; Glucose; Hyd

1985