3-hydroxybutyric acid has been researched along with Colorectal Neoplasms in 5 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Our previous structure-activity relationship studies of butyrate analogues revealed that 4-benzoylbutyrate had comparable in vitro effects to butyrate when used to treat HT29 and HCT116 colorectal cancer cell lines." | 7.78 | Identification of potential pathways involved in induction of apoptosis by butyrate and 4-benzoylbutyrate in HT29 colorectal cancer cells. ( Chung, MC; Cosgrove, LJ; Fung, KY; Head, RJ; Lewanowitsch, T; Lim, TK; Lin, Q; Lockett, TJ; Ooi, CC; Tan, HT; Tan, S; Williams, DB, 2012) |
| " Our previous structure-activity relationship studies of butyrate analogues revealed that 4-benzoylbutyrate had comparable in vitro effects to butyrate when used to treat HT29 and HCT116 colorectal cancer cell lines." | 3.78 | Identification of potential pathways involved in induction of apoptosis by butyrate and 4-benzoylbutyrate in HT29 colorectal cancer cells. ( Chung, MC; Cosgrove, LJ; Fung, KY; Head, RJ; Lewanowitsch, T; Lim, TK; Lin, Q; Lockett, TJ; Ooi, CC; Tan, HT; Tan, S; Williams, DB, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 4 (80.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dmitrieva-Posocco, O | 1 |
| Wong, AC | 1 |
| Lundgren, P | 1 |
| Golos, AM | 1 |
| Descamps, HC | 1 |
| Dohnalová, L | 1 |
| Cramer, Z | 1 |
| Tian, Y | 1 |
| Yueh, B | 1 |
| Eskiocak, O | 1 |
| Egervari, G | 1 |
| Lan, Y | 1 |
| Liu, J | 1 |
| Fan, J | 1 |
| Kim, J | 1 |
| Madhu, B | 1 |
| Schneider, KM | 1 |
| Khoziainova, S | 4 |
| Andreeva, N | 1 |
| Wang, Q | 1 |
| Li, N | 1 |
| Furth, EE | 1 |
| Bailis, W | 1 |
| Kelsen, JR | 1 |
| Hamilton, KE | 1 |
| Kaestner, KH | 1 |
| Berger, SL | 1 |
| Epstein, JA | 1 |
| Jain, R | 1 |
| Li, M | 1 |
| Beyaz, S | 1 |
| Lengner, CJ | 1 |
| Katona, BW | 1 |
| Grivennikov, SI | 1 |
| Thaiss, CA | 1 |
| Levy, M | 4 |
| Rozenberg, G | 3 |
| Mao, T | 1 |
| Qin, F | 1 |
| Zhang, M | 1 |
| Li, J | 2 |
| Lai, M | 1 |
| Fung, KY | 1 |
| Ooi, CC | 1 |
| Lewanowitsch, T | 1 |
| Tan, S | 1 |
| Tan, HT | 1 |
| Lim, TK | 1 |
| Lin, Q | 1 |
| Williams, DB | 1 |
| Lockett, TJ | 1 |
| Cosgrove, LJ | 1 |
| Chung, MC | 1 |
| Head, RJ | 1 |
5 other studies available for 3-hydroxybutyric acid and Colorectal Neoplasms
| Article | Year |
|---|---|
β-Hydroxybutyrate suppresses colorectal cancer.
Topics: 3-Hydroxybutyric Acid; Animals; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neop | 2022 |
Colorectal Cancer Growth Is Reduced by the Ketone Body β-Hydroxybutyrate.
Topics: 3-Hydroxybutyric Acid; Colorectal Neoplasms; Diet, Ketogenic; Humans; Ketone Bodies | 2022 |
Ketogenic Diet and Beta-Hydroxybutyrate in Colorectal Cancer.
Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Colorectal Neoplasms; Diet, Ketogenic; Ketone Bodi | 2022 |
Ketogenic Diet and Beta-Hydroxybutyrate in Colorectal Cancer.
Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Colorectal Neoplasms; Diet, Ketogenic; Ketone Bodi | 2022 |
Ketogenic Diet and Beta-Hydroxybutyrate in Colorectal Cancer.
Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Colorectal Neoplasms; Diet, Ketogenic; Ketone Bodi | 2022 |
Ketogenic Diet and Beta-Hydroxybutyrate in Colorectal Cancer.
Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Colorectal Neoplasms; Diet, Ketogenic; Ketone Bodi | 2022 |
Elevated serum β-hydroxybutyrate, a circulating ketone metabolite, accelerates colorectal cancer proliferation and metastasis via ACAT1.
Topics: 3-Hydroxybutyric Acid; Acetyl-CoA C-Acetyltransferase; Animals; Cell Proliferation; Colorectal Neopl | 2023 |
Identification of potential pathways involved in induction of apoptosis by butyrate and 4-benzoylbutyrate in HT29 colorectal cancer cells.
Topics: 3-Hydroxybutyric Acid; Acetylation; Antineoplastic Agents; Apoptosis; Butyrates; Cell Proliferation; | 2012 |