3-hydroxybutyric acid has been researched along with Cerebral Infarction, Middle Cerebral Artery in 6 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemic stroke is a leading cause of disability worldwide." | 1.91 | Modulation of the autophagy-lysosomal pathway and endoplasmic reticulum stress by ketone bodies in experimental models of stroke. ( Bernal-Vicente, BN; Gerónimo-Olvera, C; Gómora-García, JC; Heras-Romero, Y; Massieu, L; Montiel, T; Pérez-Martínez, X; Tovar-Y-Romo, LB, 2023) |
| "Stroke is one of the leading causes of disability and death." | 1.62 | Rational Application of β-Hydroxybutyrate Attenuates Ischemic Stroke by Suppressing Oxidative Stress and Mitochondrial-Dependent Apoptosis via Activation of the Erk/CREB/eNOS Pathway. ( Kang, Y; Li, Y; Ma, A; Zhang, X, 2021) |
| "Stroke was induced in mice by middle cerebral artery occlusion for 90 minutes, followed by reperfusion." | 1.46 | Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice. ( Berressem, D; Eckert, GP; Klein, J; Koch, K; Konietzka, J; Thinnes, A, 2017) |
| "Stroke is one of the leading causes of death." | 1.42 | Sirtuin 3 mediates neuroprotection of ketones against ischemic stroke. ( Han, P; Liu, Q; Shi, J; Tang, Z; Yin, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 3 (50.00) | 24.3611 |
| 2020's | 2 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Montiel, T | 1 |
| Gómora-García, JC | 1 |
| Gerónimo-Olvera, C | 1 |
| Heras-Romero, Y | 1 |
| Bernal-Vicente, BN | 1 |
| Pérez-Martínez, X | 1 |
| Tovar-Y-Romo, LB | 1 |
| Massieu, L | 1 |
| Li, Y | 1 |
| Zhang, X | 1 |
| Ma, A | 1 |
| Kang, Y | 1 |
| Koch, K | 1 |
| Berressem, D | 1 |
| Konietzka, J | 1 |
| Thinnes, A | 1 |
| Eckert, GP | 1 |
| Klein, J | 1 |
| Shen, Z | 1 |
| Jiang, L | 1 |
| Yuan, Y | 1 |
| Deng, T | 1 |
| Zheng, YR | 1 |
| Zhao, YY | 1 |
| Li, WL | 1 |
| Wu, JY | 1 |
| Gao, JQ | 1 |
| Hu, WW | 1 |
| Zhang, XN | 1 |
| Chen, Z | 1 |
| Yin, J | 1 |
| Han, P | 1 |
| Tang, Z | 1 |
| Liu, Q | 1 |
| Shi, J | 1 |
| Suzuki, M | 2 |
| Kitamura, Y | 1 |
| Mori, S | 1 |
| Sato, K | 1 |
| Dohi, S | 1 |
| Sato, T | 1 |
| Matsuura, A | 1 |
| Hiraide, A | 1 |
6 other studies available for 3-hydroxybutyric acid and Cerebral Infarction, Middle Cerebral Artery
| Article | Year |
|---|---|
Modulation of the autophagy-lysosomal pathway and endoplasmic reticulum stress by ketone bodies in experimental models of stroke.
Topics: 3-Hydroxybutyric Acid; Animals; Autophagy; Brain Injuries; Endoplasmic Reticulum Stress; Endoribonuc | 2023 |
Rational Application of β-Hydroxybutyrate Attenuates Ischemic Stroke by Suppressing Oxidative Stress and Mitochondrial-Dependent Apoptosis via Activation of the Erk/CREB/eNOS Pathway.
Topics: 3-Hydroxybutyric Acid; Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Ische | 2021 |
Hepatic Ketogenesis Induced by Middle Cerebral Artery Occlusion in Mice.
Topics: 3-Hydroxybutyric Acid; Adrenergic beta-Antagonists; Animals; Brain; Brain Ischemia; Citric Acid; Die | 2017 |
Inhibition of G protein-coupled receptor 81 (GPR81) protects against ischemic brain injury.
Topics: 3-Hydroxybutyric Acid; Animals; Brain Ischemia; Cell Death; Cell Hypoxia; Cell Line, Tumor; Cells, C | 2015 |
Sirtuin 3 mediates neuroprotection of ketones against ischemic stroke.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Brain Ischemia; Forkhead Box | 2015 |
Beta-hydroxybutyrate, a cerebral function improving agent, protects rat brain against ischemic damage caused by permanent and transient focal cerebral ischemia.
Topics: 3-Hydroxybutyric Acid; Animals; Brain Ischemia; Cerebral Cortex; Corpus Striatum; Infarction, Middle | 2002 |