Page last updated: 2024-10-17

3-hydroxybutyric acid and Brain Edema

3-hydroxybutyric acid has been researched along with Brain Edema in 8 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Brain Edema: Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jiang, YS1
Wang, FR1
Glaser, N1
Bundros, A1
Anderson, S1
Tancredi, D1
Lo, W1
Orgain, M1
O'Donnell, M1
Wolfsdorf, JI1
Orhan, N1
Ugur Yilmaz, C1
Ekizoglu, O1
Ahishali, B1
Kucuk, M1
Arican, N1
Elmas, I1
Gürses, C1
Kaya, M1
Righi, V1
Tugnoli, V1
Mucci, A1
Bacci, A1
Bonora, S1
Schenetti, L1
Suzuki, M2
Sato, K1
Dohi, S1
Sato, T1
Matsuura, A1
Hiraide, A1
Azzopardi, J1
Gatt, A1
Zammit, A1
Alberti, G1
Gueldry, S1
Marie, C1
Rochette, L1
Bralet, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Ketone Esters for Optimization of Cognitive Performance in Hypoxia[NCT03659825]16 participants (Anticipated)Interventional2018-09-01Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for 3-hydroxybutyric acid and Brain Edema

ArticleYear
The International Society of Pediatric and Adolescent Diabetes guidelines for management of diabetic ketoacidosis: Do the guidelines need to be modified?
    Pediatric diabetes, 2014, Volume: 15, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adolescent; Brain Edema; Child; Child, Preschool; Combined Modality Therapy;

2014

Other Studies

7 other studies available for 3-hydroxybutyric acid and Brain Edema

ArticleYear
Caloric restriction reduces edema and prolongs survival in a mouse glioma model.
    Journal of neuro-oncology, 2013, Volume: 114, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Brain Edema; Brain Neoplasms; Caloric Restriction; Cell Line, Tumor;

2013
Brain cell swelling during hypocapnia increases with hyperglycemia or ketosis.
    Pediatric diabetes, 2014, Volume: 15, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain Edema; Carbon Dioxide; Cell Size; Cerebral Cort

2014
Effects of beta-hydroxybutyrate on brain vascular permeability in rats with traumatic brain injury.
    Brain research, 2016, Jan-15, Volume: 1631

    Topics: 3-Hydroxybutyric Acid; Animals; Aquaporin 4; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries

2016
MRS study of meningeal hemangiopericytoma and edema: a comparison with meningothelial meningioma.
    Oncology reports, 2012, Volume: 28, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Aspartic Acid; Brain Edema; Choline; Creatine; Glutamic Acid; Glutat

2012
Effect of beta-hydroxybutyrate, a cerebral function improving agent, on cerebral hypoxia, anoxia and ischemia in mice and rats.
    Japanese journal of pharmacology, 2001, Volume: 87, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Blood Pressure; Body Water; Brain; Brain Ede

2001
Lack of evidence of cerebral oedema in adults treated for diabetic ketoacidosis with fluids of different tonicity.
    Diabetes research and clinical practice, 2002, Volume: 57, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Brain; Brain Edema; Diabetic Ketoacidosis; Electrolytes

2002
Beneficial effect of 1,3-butanediol on cerebral energy metabolism and edema following brain embolization in rats.
    Stroke, 1990, Volume: 21, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Water; Brain; Brain Edema; Butylene Glycols; Ene

1990