3-hydroxybutyric acid has been researched along with Blood Pressure, High in 8 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hypertension is the most important risk factor for the development of terminal cardiovascular diseases, such as heart failure, chronic kidney disease, and atherosclerosis." | 2.82 | The janus face of ketone bodies in hypertension. ( Costa, TJ; Fontes, M; Hester, S; Linder, BA; McCarthy, CG; Pernomian, L; Robinson, AT; Wenceslau, CF, 2022) |
| "Peripheral insulin resistance is a feature of essential hypertension, but there is little information about hepatic insulin sensitivity." | 1.28 | Insulin action and hepatic glucose cycling in essential hypertension. ( Atkinson, AB; Bell, NP; Bell, PM; Ennis, CN; Neely, RD; Rooney, DP; Sheridan, B; Trimble, ER, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 2 (25.00) | 24.3611 |
| 2020's | 3 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Costa, TJ | 1 |
| Linder, BA | 1 |
| Hester, S | 1 |
| Fontes, M | 1 |
| Pernomian, L | 1 |
| Wenceslau, CF | 1 |
| Robinson, AT | 1 |
| McCarthy, CG | 1 |
| Yu, Z | 1 |
| Wang, L | 1 |
| Wu, S | 1 |
| Zhao, W | 1 |
| Chakraborty, S | 2 |
| Mandal, J | 1 |
| Cheng, X | 2 |
| Galla, S | 2 |
| Hindupur, A | 1 |
| Saha, P | 2 |
| Yeoh, BS | 1 |
| Mell, B | 2 |
| Yeo, JY | 2 |
| Vijay-Kumar, M | 2 |
| Yang, T | 1 |
| Joe, B | 2 |
| Singh, V | 1 |
| Yeoh, B | 1 |
| Mathew, AV | 1 |
| Place, DE | 1 |
| Kanneganti, TD | 1 |
| Kataoka, T | 1 |
| Aoyama, Y | 1 |
| Sakoda, A | 1 |
| Nakagawa, S | 1 |
| Yamaoka, K | 1 |
| Rooney, DP | 1 |
| Neely, RD | 1 |
| Ennis, CN | 1 |
| Bell, NP | 1 |
| Sheridan, B | 1 |
| Atkinson, AB | 1 |
| Trimble, ER | 1 |
| Bell, PM | 1 |
| Peden, NR | 1 |
| Dow, RJ | 1 |
| Isles, TE | 1 |
| Martin, BT | 1 |
| Yee, KF | 1 |
| Buchanan, KD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ketone Ester and Acute Salt: Can Ketone Supplementation Prevent the Adverse Negative Effects of High Salt on Blood Vessel Health in Young Adults?[NCT05545501] | 35 participants (Anticipated) | Interventional | 2023-03-24 | Recruiting | |||
| The Effects of Ketone Ester Supplementation on Nocturnal Blood Pressure in Middle-Aged and Older Adults[NCT05888506] | 40 participants (Actual) | Interventional | 2023-08-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for 3-hydroxybutyric acid and Blood Pressure, High
| Article | Year |
|---|---|
The janus face of ketone bodies in hypertension.
Topics: 3-Hydroxybutyric Acid; Animals; Antihypertensive Agents; Hypertension; Ketone Bodies | 2022 |
Fueling Ketone Metabolism Quenches Salt-Induced Hypertension.
Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Humans; Hypertension; Ketone Bodies; Sodium Chlori | 2019 |
2 trials available for 3-hydroxybutyric acid and Blood Pressure, High
| Article | Year |
|---|---|
Basic study on biochemical mechanism of thoron and thermal therapy.
Topics: 3-Hydroxybutyric Acid; Administration, Inhalation; Adult; Atrial Natriuretic Factor; Blood Glucose; | 2006 |
The effect of chronic treatment with a non-selective beta-adrenoceptor antagonist on the enteroinsular axis and intermediary metabolites.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Alanine; Antihypertensive Agents; Blood Glucose; Clinical Trials | 1985 |
4 other studies available for 3-hydroxybutyric acid and Blood Pressure, High
| Article | Year |
|---|---|
Dissecting the potential mechanism of antihypertensive effects of RVPSL on spontaneously hypertensive rats via widely targeted kidney metabolomics.
Topics: 3-Hydroxybutyric Acid; Animals; Antihypertensive Agents; Arachidonic Acid; Biomarkers; Blood Pressur | 2023 |
Diurnal Timing Dependent Alterations in Gut Microbial Composition Are Synchronously Linked to Salt-Sensitive Hypertension and Renal Damage.
Topics: 3-Hydroxybutyric Acid; Animals; Base Sequence; Blood Pressure; Circadian Rhythm; Diet, Sodium-Restri | 2020 |
Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Pressure; Flavoring Agents; Gastrointestinal Microbiome; Hyper | 2018 |
Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Pressure; Flavoring Agents; Gastrointestinal Microbiome; Hyper | 2018 |
Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Pressure; Flavoring Agents; Gastrointestinal Microbiome; Hyper | 2018 |
Salt-Responsive Metabolite, β-Hydroxybutyrate, Attenuates Hypertension.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Pressure; Flavoring Agents; Gastrointestinal Microbiome; Hyper | 2018 |
Insulin action and hepatic glucose cycling in essential hypertension.
Topics: 3-Hydroxybutyric Acid; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose; Glucose Clamp Tec | 1992 |