Page last updated: 2024-10-17

3-hydroxybutyric acid and Astrocytoma

3-hydroxybutyric acid has been researched along with Astrocytoma in 3 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Astrocytoma: Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Mulrooney, TJ1
Marsh, J1
Urits, I1
Seyfried, TN2
Mukherjee, P2
Sanderson, TM1
El-Abbadi, MM1
McGowan, R1
Roeder, LM1
Poduslo, SE1
Tildon, JT1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma[NCT05119010]60 participants (Anticipated)Interventional2023-03-24Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

3 other studies available for 3-hydroxybutyric acid and Astrocytoma

ArticleYear
Influence of caloric restriction on constitutive expression of NF-κB in an experimental mouse astrocytoma.
    PloS one, 2011, Mar-30, Volume: 6, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytoma

2011
Role of glucose and ketone bodies in the metabolic control of experimental brain cancer.
    British journal of cancer, 2003, Oct-06, Volume: 89, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Astrocytoma; Blood Glucose; Body Weight; Caloric Restriction; Cerebe

2003
Utilization of ketone bodies and glucose by established neural cell lines.
    Journal of neuroscience research, 1982, Volume: 8, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Astrocytoma; Brain; Cell Line; Cells, Cultured; Gluco

1982