3-hydroxybutyric acid has been researched along with Apoplexy in 8 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemic stroke is a leading cause of disability worldwide." | 1.91 | Modulation of the autophagy-lysosomal pathway and endoplasmic reticulum stress by ketone bodies in experimental models of stroke. ( Bernal-Vicente, BN; Gerónimo-Olvera, C; Gómora-García, JC; Heras-Romero, Y; Massieu, L; Montiel, T; Pérez-Martínez, X; Tovar-Y-Romo, LB, 2023) |
| "Stroke is one of the leading causes of disability and death." | 1.62 | Rational Application of β-Hydroxybutyrate Attenuates Ischemic Stroke by Suppressing Oxidative Stress and Mitochondrial-Dependent Apoptosis via Activation of the Erk/CREB/eNOS Pathway. ( Kang, Y; Li, Y; Ma, A; Zhang, X, 2021) |
| "Stroke is one of the leading causes of death." | 1.42 | Sirtuin 3 mediates neuroprotection of ketones against ischemic stroke. ( Han, P; Liu, Q; Shi, J; Tang, Z; Yin, J, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 5 (62.50) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Montiel, T | 1 |
| Gómora-García, JC | 1 |
| Gerónimo-Olvera, C | 1 |
| Heras-Romero, Y | 1 |
| Bernal-Vicente, BN | 1 |
| Pérez-Martínez, X | 1 |
| Tovar-Y-Romo, LB | 1 |
| Massieu, L | 1 |
| Li, Y | 1 |
| Zhang, X | 1 |
| Ma, A | 1 |
| Kang, Y | 1 |
| Vojinovic, D | 1 |
| van der Lee, SJ | 1 |
| van Duijn, CM | 1 |
| Vernooij, MW | 1 |
| Kavousi, M | 1 |
| Amin, N | 1 |
| Demirkan, A | 1 |
| Ikram, MA | 1 |
| van der Lugt, A | 1 |
| Bos, D | 1 |
| Pikija, S | 1 |
| Trkulja, V | 1 |
| Simundic, AM | 1 |
| Vrcek, E | 1 |
| Boskovic, K | 1 |
| Bacani, S | 1 |
| Rahman, M | 1 |
| Muhammad, S | 1 |
| Khan, MA | 1 |
| Chen, H | 1 |
| Ridder, DA | 1 |
| Müller-Fielitz, H | 1 |
| Pokorná, B | 1 |
| Vollbrandt, T | 1 |
| Stölting, I | 1 |
| Nadrowitz, R | 1 |
| Okun, JG | 1 |
| Offermanns, S | 2 |
| Schwaninger, M | 2 |
| Yin, J | 1 |
| Han, P | 1 |
| Tang, Z | 1 |
| Liu, Q | 1 |
| Shi, J | 1 |
| Du Yan, S | 1 |
| Zhu, Y | 1 |
| Stern, ED | 1 |
| Hwang, YC | 1 |
| Hori, O | 1 |
| Ogawa, S | 1 |
| Frosch, MP | 1 |
| Connolly, ES | 1 |
| McTaggert, R | 1 |
| Pinsky, DJ | 1 |
| Clarke, S | 1 |
| Stern, DM | 1 |
| Ramasamy, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study Evaluating a Ketogenic Diet Concomitant to Nivolumab and Ipilimumab in Patients With Metastatic Renal Cell Carcinoma[NCT05119010] | 60 participants (Anticipated) | Interventional | 2023-03-24 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 3-hydroxybutyric acid and Apoplexy
| Article | Year |
|---|---|
Nutritional or pharmacological activation of HCA(2) ameliorates neuroinflammation.
Topics: 3-Hydroxybutyric Acid; Adenylyl Cyclases; Animals; Brain; Brain Ischemia; Diet, Ketogenic; Dimethyl | 2015 |
7 other studies available for 3-hydroxybutyric acid and Apoplexy
| Article | Year |
|---|---|
Modulation of the autophagy-lysosomal pathway and endoplasmic reticulum stress by ketone bodies in experimental models of stroke.
Topics: 3-Hydroxybutyric Acid; Animals; Autophagy; Brain Injuries; Endoplasmic Reticulum Stress; Endoribonuc | 2023 |
Rational Application of β-Hydroxybutyrate Attenuates Ischemic Stroke by Suppressing Oxidative Stress and Mitochondrial-Dependent Apoptosis via Activation of the Erk/CREB/eNOS Pathway.
Topics: 3-Hydroxybutyric Acid; Animals; Apoptosis; Brain Ischemia; Infarction, Middle Cerebral Artery; Ische | 2021 |
Metabolic profiling of intra- and extracranial carotid artery atherosclerosis.
Topics: 3-Hydroxybutyric Acid; Aged; Atherosclerosis; Calcinosis; Carotid Artery Diseases; Carotid Artery, I | 2018 |
Is on-admission capillary blood beta-hydroxybutyrate concentration associated with the acute stroke severity and short-term functional outcome?
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Aged, 80 and over; Brain Ischemia; Capillaries; Diabetes Complic | 2013 |
The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.
Topics: 3-Hydroxybutyric Acid; Animals; Brain; Diet, Ketogenic; Macrophages; Mice; Mice, Knockout; Monocytes | 2014 |
Sirtuin 3 mediates neuroprotection of ketones against ischemic stroke.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Brain Ischemia; Forkhead Box | 2015 |
Amyloid beta -peptide-binding alcohol dehydrogenase is a component of the cellular response to nutritional stress.
Topics: 3-Hydroxybutyric Acid; Alcohol Dehydrogenase; Amyloid beta-Peptides; Animals; COS Cells; Magnetic Re | 2000 |