3-hydroxybutyric acid has been researched along with Anoxemia in 21 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute hypoxia increases cerebral lactate and alanine in NG chick embryos; these increases are reduced by pre-exposure to substrate deprivation and chronic hypoxia." | 3.73 | Growth restriction and the cerebral metabolic response to acute hypoxia of chick embryos in-ovo: a proton magnetic resonance spectroscopy study. ( Cady, EB; Dixon, JC; Peebles, DM; Priest, AN; Thornton, JS, 2005) |
| "The brain mitochondrial NAD+/NADH ratio, as a reflection of the oxidation-reduction (redox) state of cellular compartment, was determined under conditions of hypoxia, anoxia, hypoxia-ischemia, complete ischemia and hypoglycemia in immature rats." | 3.69 | Cerebral mitochondrial redox states during metabolic stress in the immature rat. ( Brucklacher, RM; Vannucci, RC, 1994) |
| "With intermittent anoxia, the pattern of substrate effects on the NAP changed markedly so that low concentrations of fructose became able to support neurophysiologic activity but not high concentrations of glucose." | 1.42 | Anoxia-induced changes in optimal substrate for peripheral nerve. ( Stecker, MM; Stevenson, MR, 2015) |
| "Glycogen depletion by anoxia or glucagon before ischemia impaired recovery." | 1.29 | Metabolic recovery of isolated working rat heart after brief global ischemia. ( Goodwin, GW; Taegtmeyer, H, 1994) |
| "Hypoxemia was induced by the combination of an atrial septal defect and pulmonary stenosis." | 1.29 | Left ventricular oxygen and substrate uptake in chronically hypoxemic lambs. ( Dalinghaus, M; Gerding, AM; Gratama, C; Koers, JH; Kuipers, JR; Willem, J; Zijlstra, WG, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (14.29) | 18.7374 |
| 1990's | 8 (38.10) | 18.2507 |
| 2000's | 4 (19.05) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 1 (4.76) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, X | 1 |
| Dong, Z | 1 |
| Liu, J | 1 |
| Ma, L | 1 |
| Sun, X | 1 |
| Gao, R | 1 |
| Pan, L | 1 |
| Zhang, J | 1 |
| A, D | 1 |
| An, J | 1 |
| Hu, K | 1 |
| Sun, A | 1 |
| Ge, J | 1 |
| Boruczkowski, D | 1 |
| Pujal, JM | 1 |
| Zdolińska-Malinowska, I | 1 |
| Wang, YP | 1 |
| Wei, JY | 1 |
| Yang, JJ | 1 |
| Gao, WN | 1 |
| Wu, JQ | 1 |
| Guo, CJ | 1 |
| Takahashi, S | 1 |
| Iizumi, T | 1 |
| Mashima, K | 1 |
| Abe, T | 1 |
| Suzuki, N | 1 |
| Stecker, MM | 1 |
| Stevenson, MR | 1 |
| Lin, BQ | 1 |
| Zeng, ZY | 1 |
| Yang, SS | 1 |
| Zhuang, CW | 1 |
| Chalasani, N | 1 |
| Gorski, JC | 1 |
| Asghar, MS | 1 |
| Asghar, A | 1 |
| Foresman, B | 1 |
| Hall, SD | 1 |
| Crabb, DW | 1 |
| Dixon, JC | 1 |
| Cady, EB | 1 |
| Priest, AN | 1 |
| Thornton, JS | 1 |
| Peebles, DM | 1 |
| Sabatini, S | 1 |
| Kurtzman, NA | 1 |
| Vannucci, RC | 2 |
| Brucklacher, RM | 1 |
| Goodwin, GW | 1 |
| Taegtmeyer, H | 1 |
| Yager, JY | 1 |
| Vannucci, SJ | 1 |
| Dalinghaus, M | 1 |
| Willem, J | 1 |
| Gratama, C | 1 |
| Koers, JH | 1 |
| Gerding, AM | 1 |
| Zijlstra, WG | 1 |
| Kuipers, JR | 1 |
| Willis, N | 1 |
| Mogridge, J | 1 |
| Brooks, KJ | 1 |
| Clark, JB | 1 |
| Bates, TE | 1 |
| Van Cappellen Van Walsum, AM | 1 |
| Jongsma, HW | 1 |
| Wevers, RA | 1 |
| Nijhuis, JG | 1 |
| Crevels, J | 1 |
| Engelke, UF | 1 |
| De Abreu, RA | 1 |
| Moolenaar, SH | 1 |
| Oeseburg, B | 1 |
| Nijland, R | 1 |
| Arnould, T | 1 |
| Michiels, C | 1 |
| Alexandre, I | 1 |
| Remacle, J | 1 |
| D'Alecy, LG | 2 |
| Lundy, EF | 1 |
| Kluger, MJ | 1 |
| Harker, CT | 1 |
| LeMay, DR | 1 |
| Shlafer, M | 1 |
| Bossi, E | 1 |
| Kohler, E | 1 |
| Herschkowitz, N | 1 |
| Rising, CL | 1 |
| Ishikawa, S | 1 |
| Vassalle, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Fish Oil and Diet for the Treatment of Non-Alcoholic Steatohepatitis (NASH)[NCT00845845] | Phase 2 | 12 participants (Actual) | Interventional | 2006-03-31 | Terminated (stopped due to Terminated due to low enrollment.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 3-hydroxybutyric acid and Anoxemia
| Article | Year |
|---|---|
Autologous cord blood in children with cerebral palsy: a review.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Brain Diseases; Brain Injuries; Carnitine; Cerebral Pal | 2019 |
20 other studies available for 3-hydroxybutyric acid and Anoxemia
| Article | Year |
|---|---|
β-Hydroxybutyrate Exacerbates Hypoxic Injury by Inhibiting HIF-1α-Dependent Glycolysis in Cardiomyocytes-Adding Fuel to the Fire?
Topics: 3-Hydroxybutyric Acid; Animals; Disease Models, Animal; Glucose; Glycolysis; Humans; Hypoxia; Hypoxi | 2022 |
Riboflavin supplementation improves energy metabolism in mice exposed to acute hypoxia.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Carnitine; Dietary Supplements; Drug Evaluation, Prec | 2014 |
Roles and regulation of ketogenesis in cultured astroglia and neurons under hypoxia and hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Astrocytes; Carbon Isotopes; Carnitine; Cells, Cultur | 2014 |
Anoxia-induced changes in optimal substrate for peripheral nerve.
Topics: 3-Hydroxybutyric Acid; Acetates; Action Potentials; Animals; Fructose; Galactose; Glucose; Hypoxia; | 2015 |
Dietary restriction suppresses tumor growth, reduces angiogenesis, and improves tumor microenvironment in human non-small-cell lung cancer xenografts.
Topics: 3-Hydroxybutyric Acid; Actins; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferatio | 2013 |
Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis.
Topics: 3-Hydroxybutyric Acid; Adult; Blood Glucose; Body Mass Index; Chlorzoxazone; Cholesterol, HDL; Cytoc | 2003 |
Growth restriction and the cerebral metabolic response to acute hypoxia of chick embryos in-ovo: a proton magnetic resonance spectroscopy study.
Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Aspartic Acid; Cerebellum; Chick Embryo; Fetal Hypoxia; Hyp | 2005 |
Bicarbonate therapy in severe metabolic acidosis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Bicarbonates; Cell Death; Diabetic Ketoacidosis; Hum | 2009 |
Cerebral mitochondrial redox states during metabolic stress in the immature rat.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Animals, Newborn; Brain; Brain Diseases; Brain Ischem | 1994 |
Metabolic recovery of isolated working rat heart after brief global ischemia.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Fasting; Glucose-6-Phosphate; Glucosephospha | 1994 |
Cerebral glucose and energy utilization during the evolution of hypoxic-ischemic brain damage in the immature rat.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Animals, Newborn; Brain; Brain Ischemia; Energy Metab | 1994 |
Left ventricular oxygen and substrate uptake in chronically hypoxemic lambs.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Pressure; Carbon Dioxide; Coronary Circulation; Coronary Vesse | 1993 |
Indicators of histohypoxia.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Carbon Dioxide; Cardiac Output; Cell Hypoxia; Cell Survival; C | 1995 |
3-Hydroxybutyrate aids the recovery of the energy state from aglycaemic hypoxia of adult but not neonatal rat brain slices.
Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Blood Glucose; Brain; Energy Metabolism; Female; H | 1998 |
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Femal | 2002 |
Effect of hypoxia upon intracellular calcium concentration of human endothelial cells.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Calcium; Cell Survival; Cells, Cultured; Endothelium, | 1992 |
Beta-hydroxybutyrate and response to hypoxia in the ground squirrel, Spermophilus tridecimlineatus.
Topics: 3-Hydroxybutyric Acid; Animals; Hibernation; Hydroxybutyrates; Hypoxia; In Vitro Techniques; Ketones | 1990 |
Utilization of D-beta-hydroxybutyrate and oleate as alternate energy fuels in brain cell cultures of newborn mice after hypoxia at different glucose concentrations.
Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Brain; Carbon Dioxide; Cells, Cultured; Energy Met | 1989 |
Hypoxia-induced increases in hypoxic tolerance augmented by beta-hydroxybutyrate in mice.
Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Temperature; Glucose; Hydroxybutyrates; Hypoxia; | 1989 |
Reversal of strophanthidin negative inotropy by metabolic substrates in cardiac Purkinje fibres.
Topics: 3-Hydroxybutyric Acid; Action Potentials; Animals; Calcium; Depression, Chemical; Dogs; Female; Gluc | 1985 |