3-hydroxybutyric acid has been researched along with Amyotrophic Lateral Sclerosis in 4 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paoli, A | 1 |
| Bianco, A | 1 |
| Damiani, E | 1 |
| Bosco, G | 1 |
| Blasco, H | 1 |
| Błaszczyński, J | 1 |
| Billaut, JC | 1 |
| Nadal-Desbarats, L | 1 |
| Pradat, PF | 1 |
| Devos, D | 1 |
| Moreau, C | 1 |
| Andres, CR | 1 |
| Emond, P | 1 |
| Corcia, P | 1 |
| Słowiński, R | 1 |
| Kumar, A | 1 |
| Bala, L | 1 |
| Kalita, J | 1 |
| Misra, UK | 1 |
| Singh, RL | 1 |
| Khetrapal, CL | 1 |
| Babu, GN | 1 |
| Sanjak, M | 1 |
| Paulson, D | 1 |
| Sufit, R | 1 |
| Reddan, W | 1 |
| Beaulieu, D | 1 |
| Erickson, L | 1 |
| Shug, A | 1 |
| Brooks, BR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized-controlled Study for Evaluation of Ketogenic Metabolic Nutritional Pattern in Subjects With High-frequency Episodic Migraine[NCT04360148] | 58 participants (Anticipated) | Interventional | 2020-02-06 | Active, not recruiting | |||
| Ketogenic Diet Interventions in Parkinson's Disease: Safeguarding the Gut Microbiome[NCT05469997] | 50 participants (Anticipated) | Interventional | 2023-01-31 | Not yet recruiting | |||
| Ketogenic Diet in McArdle Disease: a Multicentric Single Blind Controlled Trial[NCT04292938] | 16 participants (Actual) | Interventional | 2019-03-25 | Completed | |||
| The Safety and Effects on Whole Organism of Low Energy Ketogenic Diet for Weight Loss in Obese Subjects[NCT03338452] | 38 participants (Actual) | Interventional | 2017-03-18 | Completed | |||
| The Role of Moderate Aerobic Exercise as Determined by Cardiopulmonary Exercise Testing in ALS[NCT03326622] | 48 participants (Actual) | Interventional | 2013-07-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 3-hydroxybutyric acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
Ketogenic diet in neuromuscular and neurodegenerative diseases.
Topics: 3-Hydroxybutyric Acid; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Brain; Diet, Ketogenic; Glu | 2014 |
3 other studies available for 3-hydroxybutyric acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Comparative analysis of targeted metabolomics: dominance-based rough set approach versus orthogonal partial least square-discriminant analysis.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetone; Aged; Algorithms; Amyotrophic Lateral Sclerosis; Bayes The | 2015 |
Metabolomic analysis of serum by (1) H NMR spectroscopy in amyotrophic lateral sclerosis.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetone; Adult; Amyotrophic Lateral Sclerosis; Female; Formates; Gl | 2010 |
Physiologic and metabolic response to progressive and prolonged exercise in amyotrophic lateral sclerosis.
Topics: 3-Hydroxybutyric Acid; Amyotrophic Lateral Sclerosis; Carnitine; Exercise Test; Fatty Acids, Noneste | 1987 |