Page last updated: 2024-10-17

3-hydroxybutyric acid and Alloxan Diabetes

3-hydroxybutyric acid has been researched along with Alloxan Diabetes in 107 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Research Excerpts

ExcerptRelevanceReference
"In the diabetic ketoacidosis series, treatment with either alkali resulted in deterioration of mean arterial blood pressure and substantial elevation of blood lactate, despite a significant rise in myocardial intracellular pH determined by 31P-magnetic resonance spectroscopy."5.29Haemodynamic and metabolic effects in diabetic ketoacidosis in rats of treatment with sodium bicarbonate or a mixture of sodium bicarbonate and sodium carbonate. ( Beech, JS; Cohen, RD; Evans, SJ; Going, TC; Iles, RA; Nolan, KM; Williams, SC, 1995)
"Leptin can reverse hyperglycemia in rodent models of type 1 diabetes."3.83Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy. ( Covey, SD; Denroche, HC; Kieffer, TJ; Mojibian, M; Neumann, UH, 2016)
" We further demonstrate that activation of FXR in db/db mice repressed hepatic gluconeogenic genes and increased hepatic glycogen synthesis and glycogen content by a mechanism that involves enhanced insulin sensitivity."3.73Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice. ( Barrera, G; Edwards, PA; Gonzalez, FJ; Lee, FY; Lee, H; Vales, C; Willson, TM; Zhang, Y, 2006)
"To elucidate the peripheral disposal of ketone bodies in hyperketonemia accompanied with starvation, hyperthyroidism, or diabetes mellitus, the uptake of acetoacetic acid (AcAc) and beta-hydroxybutyrate (BOHB) was investigated in the perfused hindquarter and kidney of starved, thyrotoxic, and diabetic rats."3.68Uptake of ketone bodies in perfused hindquarter and kidney of starved, thyrotoxic, and diabetic rats. ( Fujiyama, K; Hoshino, T; Ikeda, T; Ishimura, M; Mashiba, H; Ochi, H; Ohtani, I; Tanaka, Y; Terasawa, H, 1993)
"The plasma concentration of arginine vasopressin (AVP) is increased in diabetic ketoacidosis (DKA) in man and the rat."3.67Possible mechanisms responsible for the rise in plasma vasopressin associated with diabetic ketoacidosis in the rat. ( Baylis, PH; Charlton, JA; Thompson, CJ, 1988)
" To test the role of beta-hydroxybutyric acid (BHB) and acidosis in generating such changes, we studied the pituitary-thyroid axis of streptozotocin-diabetic rats, BHB or ammonium chloride (NH4Cl)-treated normal rats."3.67Effects of diabetes, beta-hydroxybutyric acid and metabolic acidosis on the pituitary-thyroid axis in the rat. ( Boado, R; Colombo, O; Zaninovich, AA, 1985)
"However, existing therapeutics for type 2 diabetes mellitus have limited success on the prevention of diabetic cardiomyopathy."1.62Ketone Ester D-β-Hydroxybutyrate-(R)-1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice. ( Bers, DM; Chiamvimonvat, N; Dedkova, EN; King, MT; Miller, CV; Schaefer, S; Thai, PN; Veech, RL, 2021)
"The resulting hyperglycemia is very difficult to treat, and patients are at risk for early morbidity and mortality from complications of diabetes."1.46Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice. ( Cavino, K; Cheng, X; Gromada, J; Kim, SY; Krumm, E; Murphy, AJ; Na, E; Okamoto, H; Yancopoulos, GD, 2017)
") implantation, its therapeutic effect lasted for over 130 h, and its bioavailability was enhanced by 4-fold."1.39The implantable and biodegradable PHBHHx 3D scaffolds loaded with protein-phospholipid complex for sustained delivery of proteins. ( Gong, T; Peng, Q; Sun, X; Wu, CY; Yang, Q; Yang, YJ; Zhang, L; Zhang, T; Zhang, ZR, 2013)
"As L-carnitine plays a pivotal role in the balanced metabolism of fatty acids and carbohydrates, this study was carried out to investigate whether long-term mildronate treatment could influence glucose levels and prevent diabetic complications in an experimental model of type 2 diabetes in Goto-Kakizaki (GK) rats."1.35Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats. ( Cirule, H; Dambrova, M; Grinberga, S; Kalvinsh, I; Kuka, J; Liepinsh, E; Skapare, E; Svalbe, B; Vilskersts, R; Zvejniece, L, 2009)
"Diabetic TPN rats without insulin treatment had weight loss and negative nitrogen balance during the experiment."1.30MCT/LCT emulsion ameliorate liver fat deposition in insulin-treated diabetic rats receiving total parenteral nutrition. ( Chen, WJ; Lin, MT; Yeh, SL, 1998)
" In conclusion, this study suggests that short-term administration of LA at high dosage to normal and diabetic rats causes an inhibition of gluconeogenesis secondary to an interference with hepatic fatty acid oxidation."1.30Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats. ( Bashan, N; Gutman, A; Khamaisi, M; Potashnik, R; Rudich, A; Tritschler, HJ, 1999)
"In the diabetic ketoacidosis series, treatment with either alkali resulted in deterioration of mean arterial blood pressure and substantial elevation of blood lactate, despite a significant rise in myocardial intracellular pH determined by 31P-magnetic resonance spectroscopy."1.29Haemodynamic and metabolic effects in diabetic ketoacidosis in rats of treatment with sodium bicarbonate or a mixture of sodium bicarbonate and sodium carbonate. ( Beech, JS; Cohen, RD; Evans, SJ; Going, TC; Iles, RA; Nolan, KM; Williams, SC, 1995)

Research

Studies (107)

TimeframeStudies, this research(%)All Research%
pre-199041 (38.32)18.7374
1990's38 (35.51)18.2507
2000's13 (12.15)29.6817
2010's9 (8.41)24.3611
2020's6 (5.61)2.80

Authors

AuthorsStudies
Thai, PN1
Miller, CV1
King, MT1
Schaefer, S1
Veech, RL1
Chiamvimonvat, N1
Bers, DM1
Dedkova, EN1
Trotta, MC1
Gesualdo, C1
Herman, H1
Gharbia, S1
Balta, C1
Lepre, CC1
Russo, M1
Itro, A1
D'Amico, G1
Peluso, L1
Panarese, I1
Pieretti, G1
Ferraro, G1
Simonelli, F1
D'Amico, M1
Rossi, S1
Hermenean, A1
Zhang, F2
Wang, S1
Zhao, C1
Jiang, D1
Wang, Y2
Qi, J4
Li, Y5
Wu, X1
Miao, D1
Liu, Z1
Liu, K3
Zhang, B1
Li, J1
Li, B1
Yu, Y1
Zhang, Y2
Geng, Q1
Qi, H1
Gu, L1
Xu, D1
Zhou, M1
Wang, X1
Sadek, KM1
Shaheen, H1
Glaser, N1
Bundros, A1
Anderson, S1
Tancredi, D1
Lo, W1
Orgain, M1
O'Donnell, M1
Neumann, UH1
Denroche, HC1
Mojibian, M1
Covey, SD1
Kieffer, TJ1
Okamoto, H1
Cavino, K1
Na, E1
Krumm, E1
Kim, SY1
Cheng, X1
Murphy, AJ1
Yancopoulos, GD1
Gromada, J1
Liu, Y1
Chen, G2
Liepinsh, E1
Vilskersts, R1
Zvejniece, L1
Svalbe, B1
Skapare, E1
Kuka, J1
Cirule, H1
Grinberga, S1
Kalvinsh, I1
Dambrova, M1
Barrena, HC1
Gazola, VA1
Furlan, MM1
Garcia, RF1
de Souza, HM1
Bazotte, RB1
Hsu, WY1
Kuo, CY1
Fukushima, T2
Imai, K2
Chen, CM1
Lin, PY1
Lee, JA2
Gambhir, D1
Ananth, S1
Veeranan-Karmegam, R1
Elangovan, S1
Hester, S1
Jennings, E1
Offermanns, S1
Nussbaum, JJ1
Smith, SB1
Thangaraju, M1
Ganapathy, V1
Martin, PM1
Yamai, K1
Funada, T1
Ohkuwa, T1
Itoh, H1
Tsuda, T1
Peng, Q1
Yang, YJ1
Zhang, T1
Wu, CY1
Yang, Q1
Sun, X1
Gong, T1
Zhang, L1
Zhang, ZR1
Giannessi, F1
Pessotto, P1
Tassoni, E1
Chiodi, P1
Conti, R1
De Angelis, F1
Dell'Uomo, N1
Catini, R1
Deias, R1
Tinti, MO1
Carminati, P1
Arduini, A1
Linke, A1
Zhao, G1
Recchia, FA1
Williams, J1
Xu, X1
Hintze, TH1
Olson, DE1
Paveglio, SA1
Huey, PU1
Porter, MH1
Thulé, PM1
El Midaoui, A3
Chiasson, JL2
Tancrède, G3
Nadeau, A3
Otero, P1
Bonet, B2
Herrera, E3
Rabano, A1
Lee, FY1
Barrera, G1
Lee, H1
Vales, C1
Gonzalez, FJ1
Willson, TM1
Edwards, PA1
Herberg, L1
Buchanan, KD1
Hermansen, K1
Lefebvre, PJ1
Luyckx, AS1
Scheen, AJ1
Castillo, M1
Jandrain, B1
Krzentowski, G1
Stangassinger, M1
Peruche, T1
Giesecke, D1
Hutson, JC1
Diani, AR2
Peterson, T2
Gilchrist, BJ1
Stevenson, RW2
Orskov, H1
Parsons, JA2
Alberti, KG2
Dahlkvist, HH3
Arnqvist, HJ2
Norrby, K2
Ogihara, M1
Tokumitsu, Y1
Ui, M1
Chen, V1
Wagner, G1
Spitzer, JJ1
Kasser, TR1
Gahagan, JH1
Martin, RJ1
Kielducka, A1
Paradies, G1
Papa, S1
Beech, JS2
Williams, SC1
Iles, RA2
Cohen, RD2
Nolan, KM1
Evans, SJ1
Going, TC1
Shin, M1
Maeda, S1
Hashimoto, Y1
Sano, K1
Umezawa, C1
Sultan, AM2
Szutowicz, A1
Tomaszewicz, M1
Jankowska, A1
Kisielevski, Y1
Buchanan, TA1
Denno, KM1
Sipos, GF1
Sadler, TW2
Moley, KH1
Vaughn, WK1
Diamond, MP1
Gibson, R1
Zhao, Y1
Jaskiewicz, J1
Fineberg, SE1
Harris, RA1
Cole, DR1
Waterfall, M1
Ashworth, L1
Bone, AJ1
Baird, JD1
Nakao, M1
Matsubara, T1
Sakamoto, N3
Shi, ZQ1
Giacca, A1
Yamatani, K1
Fisher, SJ1
Lickley, HL1
Vranic, M1
Hotta, N2
Komori, T1
Kobayashi, M1
Sakakibara, F1
Koh, N2
Ikeda, T2
Ishimura, M1
Terasawa, H1
Ochi, H1
Ohtani, I2
Fujiyama, K2
Hoshino, T2
Tanaka, Y2
Mashiba, H2
Wentzel, P1
Eriksson, UJ4
Jiffri, E1
Broom, J1
Whiting, PH1
McLean, MP1
Warden, KJ1
Sandhoff, TW1
Irby, RB1
Hales, DB1
Brignone, JA1
de Brignone, CM1
Ricci, CR1
de Mignone, IR1
Susemihl, MC1
Rodríguez, RR1
Viana, M1
Fischer, Y1
Böttcher, U1
Eblenkamp, M1
Thomas, J1
Jüngling, E1
Rösen, P1
Kammermeier, H1
Shimabukuro, M1
Koyama, K1
Wang, MY1
Trieu, F1
Lee, Y1
Newgard, CB1
Unger, RH1
Forsberg, H1
Melefors, O1
Welsh, N1
Oshida, Y2
Iwao, N1
Ohsawa, I2
Sato, J2
Nakao, T1
Sato, Y2
Nakai, N1
Shimomura, Y1
Rodríguez, T1
Busquets, S1
Alvarez, B1
Agell, N1
Lpez-Soriano, FJ1
Argilś, JM1
Yeh, SL1
Lin, MT1
Chen, WJ1
Khamaisi, M1
Rudich, A1
Potashnik, R1
Tritschler, HJ1
Gutman, A1
Bashan, N1
Ladrière, L1
Malaisse, WJ2
Lapidot, A2
Haber, S2
Korenaga, T1
Ichihara, H1
Kato, M1
Ferré, P2
Pénicaud, L2
Hitier, Y1
Meier, M1
Girard, J2
Mori, K1
Kaku, K1
Inoue, H1
Aoki, M1
Matsutani, A1
Kaneko, T1
Elayan, IM1
Cartmill, DC1
Eckersell, CB1
Wilkin, J1
Winder, WW1
Ramirez, R1
Sener, A1
Takeuchi, T1
Feingold, KR1
Soued, M1
Adi, S1
Staprans, I1
Shigenaga, J1
Doerrler, W1
Moser, A1
Grunfeld, C1
Weinstein, I1
Patel, TB1
Heimberg, M1
Kaloyianni, M1
Freedland, RA1
Bailey, JW1
Haymond, MW1
Miles, JM1
Styrud, J2
Avogaro, A1
Nosadini, R1
Doria, A1
Tremolada, C1
Baccaglini, U1
Ambrosio, F1
Merkel, C1
Nosadini, A1
Trevisan, R1
Fioretto, P1
Williams, SR1
Kamei, I1
Kakuta, H1
Kimura, M1
Fukasawa, H1
Moore, DC1
Stanisstreet, M1
Clarke, CA1
Baudon, MA1
Maulard, P1
Ktorza, A1
Castano, L1
Hofert, JF1
Goldstein, S1
Phillips, LS3
Hunter, ES1
Wynn, RE1
Hawkins, RA1
Mans, AM1
Davis, DW1
McCall, AL1
Sussman, I1
Tornheim, K1
Cordero, R1
Ruderman, NB1
Gil, J1
Carreras, J1
Bartrons, R1
Okuda, Y1
Kawai, K1
Yamashita, K1
Nagy, LE1
Kretchmer, N1
Charlton, JA1
Thompson, CJ1
Baylis, PH1
Fusco, AC1
Unterman, TG1
Boado, R1
Colombo, O1
Zaninovich, AA1
Bellward, GD1
Chang, T1
Rodrigues, B1
McNeill, JH1
Maines, S1
Ryan, DE1
Levin, W1
Thomas, PE1
Grantham, BD1
Zammit, VA1
Spanheimer, RG1
Freed, LE1
Endemann, G1
Tomera, JF1
Gavino, VC1
Brunengraber, H1
Albisser, AM1
Nomura, M1
McPhedran, NT1
Zusman, I1
Yaffe, P1
Ornoy, A1
Bedetti, CD1
Montero, GA1
Stoppani, AO1
Karlsson, MG1
Young, JC1
Treadway, JL1
Fader, EI1
Caslin, RF1
Cheng, L1
el-Seifi, S1
Sacktor, B1
Palacin, M1
Martin, A1
Lasuncion, MA1
Sawada, GA1
Wyse, BM1
Blanks, MC1
Gerritsen, GC1
Terenghi, G1
Varndell, IM1
Polak, JM1
Blank, MA1

Reviews

2 reviews available for 3-hydroxybutyric acid and Alloxan Diabetes

ArticleYear
[Metabolic consequences of insulin deficiency].
    Journees annuelles de diabetologie de l'Hotel-Dieu, 1984

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Humans; Hydroxybutyr

1984
Mechanisms of congenital malformations in diabetic pregnancy.
    Biology of the neonate, 1987, Volume: 51, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Congenital Abnormalities; Diabetes Mellitus, Experime

1987

Other Studies

105 other studies available for 3-hydroxybutyric acid and Alloxan Diabetes

ArticleYear
Ketone Ester D-β-Hydroxybutyrate-(R)-1,3 Butanediol Prevents Decline in Cardiac Function in Type 2 Diabetic Mice.
    Journal of the American Heart Association, 2021, 10-05, Volume: 10, Issue:19

    Topics: 3-Hydroxybutyric Acid; Animals; Butylene Glycols; Diabetes Mellitus, Experimental; Diabetes Mellitus

2021
Systemic Beta-Hydroxybutyrate Affects BDNF and Autophagy into the Retina of Diabetic Mice.
    International journal of molecular sciences, 2022, Sep-05, Volume: 23, Issue:17

    Topics: 3-Hydroxybutyric Acid; Animals; Autophagy; Brain-Derived Neurotrophic Factor; Connexin 43; Diabetes

2022
D-beta-hydroxybutyrate reduced the enhanced cardiac microvascular endothelial FoxO1 to play protective roles in diabetic rats and high glucose-stimulated human cardiac microvascular endothelial cells.
    Tissue & cell, 2023, Volume: 81

    Topics: 3-Hydroxybutyric Acid; Animals; Claudin-5; Diabetes Mellitus, Experimental; Endothelial Cells; Forkh

2023
β-hydroxybutyrate antagonizes aortic endothelial injury by promoting generation of VEGF in diabetic rats.
    Tissue & cell, 2020, Volume: 64

    Topics: 3-Hydroxybutyric Acid; Animals; Aorta; Diabetes Mellitus, Experimental; Endothelium, Vascular; Histo

2020
β-Hydroxybutyrate inhibits histone deacetylase 3 to promote claudin-5 generation and attenuate cardiac microvascular hyperpermeability in diabetes.
    Diabetologia, 2021, Volume: 64, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; beta Catenin; Capillary Permeability; Claudin-5; Coronary Vessels; D

2021
β-Hydroxybutyrate inhibits cardiac microvascular collagen 4 accumulation by attenuating oxidative stress in streptozotocin-induced diabetic rats and high glucose treated cells.
    European journal of pharmacology, 2021, May-15, Volume: 899

    Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Cells, Cultured; Collagen Type IV; Coronary Vessels; D

2021
Biochemical efficacy of vitamin D in ameliorating endocrine and metabolic disorders in diabetic rats.
    Pharmaceutical biology, 2014, Volume: 52, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, T

2014
Brain cell swelling during hypocapnia increases with hyperglycemia or ketosis.
    Pediatric diabetes, 2014, Volume: 15, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Brain Edema; Carbon Dioxide; Cell Size; Cerebral Cort

2014
Insulin Knockout Mice Have Extended Survival but Volatile Blood Glucose Levels on Leptin Therapy.
    Endocrinology, 2016, Volume: 157, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Corticosterone; Diabetes Mellitus, Exper

2016
Glucagon receptor inhibition normalizes blood glucose in severe insulin-resistant mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2017, 03-07, Volume: 114, Issue:10

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glucagon; Glucagon-S

2017
Vitamin A status affects the plasma parameters and regulation of hepatic genes in streptozotocin-induced diabetic rats.
    Biochimie, 2017, Volume: 137

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Blotting, Western; Cells, Cultured; Diabetes Mellitus

2017
Protective effects of mildronate in an experimental model of type 2 diabetes in Goto-Kakizaki rats.
    British journal of pharmacology, 2009, Volume: 157, Issue:8

    Topics: 3-Hydroxybutyric Acid; Administration, Oral; Animals; Blood Glucose; Cardiovascular Agents; Carnitin

2009
Ketogenesis evaluation in perfused liver of diabetic rats submitted to short-term insulin-induced hypoglycemia.
    Cell biochemistry and function, 2009, Volume: 27, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Caprylates; Diabetes Mellitus, Experim

2009
Enantioselective determination of 3-hydroxybutyrate in the tissues of normal and streptozotocin-induced diabetic rats of different ages.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2011, Nov-01, Volume: 879, Issue:29

    Topics: 3-Hydroxybutyric Acid; Age Factors; Analysis of Variance; Animals; Blood Glucose; Body Weight; Chrom

2011
GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.
    Investigative ophthalmology & visual science, 2012, Apr-24, Volume: 53, Issue:4

    Topics: 3-Hydroxybutyric Acid; Aged; Animals; Cell Line; Chemokine CCL2; Diabetes Mellitus, Experimental; Di

2012
Acetone concentration in gas emanating from tails of diabetic rats.
    Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 2012, Volume: 28, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetone; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gases; Male

2012
The implantable and biodegradable PHBHHx 3D scaffolds loaded with protein-phospholipid complex for sustained delivery of proteins.
    Pharmaceutical research, 2013, Volume: 30, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Biocompatible Materials; Caproates; Delayed-Action Preparations; Dia

2013
Discovery of a long-chain carbamoyl aminocarnitine derivative, a reversible carnitine palmitoyltransferase inhibitor with antiketotic and antidiabetic activity.
    Journal of medicinal chemistry, 2003, Jan-16, Volume: 46, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Butyrates; Carnitine; Carnitine O-Palmitoyltransferas

2003
Shift in metabolic substrate uptake by the heart during development of alloxan-induced diabetes.
    American journal of physiology. Heart and circulatory physiology, 2003, Volume: 285, Issue:3

    Topics: 3-Hydroxybutyric Acid; Alloxan; Animals; Blood Glucose; Blood Pressure; Body Weight; Carbon Dioxide;

2003
Glucose-responsive hepatic insulin gene therapy of spontaneously diabetic BB/Wor rats.
    Human gene therapy, 2003, Oct-10, Volume: 14, Issue:15

    Topics: 3-Hydroxybutyric Acid; Adenoviridae; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Enzyme

2003
Physical training reverses defect in 3-ketoacid CoA-transferase activity in skeletal muscle of diabetic rats.
    American journal of physiology. Endocrinology and metabolism, 2005, Volume: 288, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Coenzyme A-Transferases; Diabetes Mellit

2005
Development of atherosclerosis in the diabetic BALB/c mice. Prevention with Vitamin E administration.
    Atherosclerosis, 2005, Volume: 182, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Antioxidants; Arteries; Atherosclerosis; Blood Glucose; Body Weight;

2005
Physical training reverses the increased activity of the hepatic ketone body synthesis pathway in chronically diabetic rats.
    American journal of physiology. Endocrinology and metabolism, 2006, Volume: 290, Issue:2

    Topics: 3-Hydroxybutyric Acid; Adaptation, Physiological; Animals; Chronic Disease; Diabetes Mellitus, Exper

2006
Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Jan-24, Volume: 103, Issue:4

    Topics: 3-Hydroxybutyric Acid; Adenoviridae; Animals; Blood Glucose; Blotting, Northern; Blotting, Western;

2006
Effect of high glucagon infusions on blood glucose, plasma insulin and beta-OH-butyrate concentrations in streptozotocin-diabetic and normal Osborne Mendel rats.
    Comparative biochemistry and physiology. A, Comparative physiology, 1982, Volume: 72, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female; Glucagon; Hy

1982
Stimulatory effect of beta-hydroxybutyrate on the release of somatostatin from the isolated pancreas of normal and streptozotocin-diabetic dogs.
    Diabetes, 1982, Volume: 31, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Bicarbonates; Blood Glucose; Diabetes Mellitus, Experimental; Dogs;

1982
[Diabetes mellitus in dwarf goats; model experiments with streptozocin].
    Zentralblatt fur Veterinarmedizin. Reihe A, 1982, Volume: 29, Issue:4-5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Goats

1982
Altered biochemical responses by rat Sertoli cells and peritubular cells cultured under simulated diabetic conditions.
    Diabetologia, 1984, Volume: 26, Issue:2

    Topics: 3-Hydroxybutyric Acid; Androgen-Binding Protein; Animals; Bicarbonates; Carrier Proteins; Cells, Cul

1984
Islet innervation of nondiabetic and diabetic Chinese hamsters. I. Acetylcholinesterase histochemistry and norepinephrine fluorescence.
    Journal of neural transmission, 1983, Volume: 56, Issue:2-3

    Topics: 3-Hydroxybutyric Acid; Acetylcholinesterase; Adrenergic Fibers; Animals; Blood Glucose; Cholinergic

1983
Metabolic responses to intraduodenal glucose loading in insulin-infused diabetic dogs.
    The American journal of physiology, 1983, Volume: 245, Issue:2

    Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Fatty

1983
Effect of elevated substrates on substrate oxidation in normal and diabetic aorta.
    Acta physiologica Scandinavica, 1983, Volume: 119, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Aorta; Diabetes Mellitus, Experimental; Glucose; Hydroxybutyrates; M

1983
Effects of diabetes on glucose oxidation in rat aorta after hypophysectomy and adrenalectomy.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adrenal Glands; Adrenalectomy; Animals; Aorta; Blood Glucose; Blood Vessels;

1984
Metabolic alterations in normal and streptozotocin-diabetic rats in vivo: influence of prolonged starvation.
    Japanese journal of pharmacology, 1984, Volume: 34, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Carbohydrate Metabolism; Diabetes Mellitus, Experimen

1984
Regulation of substrate oxidation in isolated myocardial cells by beta-hydroxybutyrate.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Caprylates; Cells, Cultured; Diabetes Mellitus, Experimental; Hydrox

1984
Comparison of the metabolic responses to portal and peripheral infusions of insulin in diabetic dogs.
    Metabolism: clinical and experimental, 1981, Volume: 30, Issue:8

    Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dogs; Gluca

1981
Influence of diabetes on oxidation of exogenous substrates in rat aorta.
    Diabete & metabolisme, 1981, Volume: 7, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Aorta; Diabetes Mellitus, Experimental; Glucose; Hydroxybutyrates; I

1981
Fetal hormones and neonatal survival in response to altered maternal serum glucose and free fatty acid concentrations in pigs.
    Journal of animal science, 1982, Volume: 55, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Animals, Newborn; Blood Glucose; Diabetes Mellitus, Experimental; Fa

1982
A comparative study of the transport of pyruvate in liver mitochondria from normal and diabetic rats.
    Journal of bioenergetics and biomembranes, 1981, Volume: 13, Issue:3-4

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Biological Transport; Blood Glucose; Diabetes Mellitu

1981
Haemodynamic and metabolic effects in diabetic ketoacidosis in rats of treatment with sodium bicarbonate or a mixture of sodium bicarbonate and sodium carbonate.
    Diabetologia, 1995, Volume: 38, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Pressure; Carbon Dioxide; Carbonates; Diabetes Mellitus, Exper

1995
NAD synthesis from nicotinic acid by the hepatocytes prepared from diabetic rats.
    International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition, 1995, Volume: 65, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Carbon Radioisotopes; Cells, Cultured;

1995
The effects of chronic diabetes and physiological insulin concentration on ketone bodies metabolism in the heart.
    Diabetes research (Edinburgh, Scotland), 1994, Volume: 27, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diabetes Mellitus, Experimental; Dose-Response Relati

1994
Acetylcholine synthesis in nerve terminals of diabetic rats.
    Neuroreport, 1994, Dec-20, Volume: 5, Issue:18

    Topics: 3-Hydroxybutyric Acid; Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Diabetes Mellitus, Experime

1994
Diabetic teratogenesis. In vitro evidence for a multifactorial etiology with little contribution from glucose per se.
    Diabetes, 1994, Volume: 43, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Congenital Abnormalities; Diabetes Mellitus, Experime

1994
Manifestations of diabetes mellitus on mouse preimplantation development: effect of elevated concentration of metabolic intermediates.
    Human reproduction (Oxford, England), 1994, Volume: 9, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Amino Acids; Animals; Butyrates; Cleavage Stage, Ovum; Culture

1994
Effects of diabetes on the activity and content of the branched-chain alpha-ketoacid dehydrogenase complex in liver.
    Archives of biochemistry and biophysics, 1993, Volume: 306, Issue:1

    Topics: 3-Hydroxybutyric Acid; 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Acetoacetates; Animals; Bl

1993
Metabolic control in streptozotocin diabetic rats following transplantation of microencapsulated pancreatic islets.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1993, Volume: 25, Issue:11

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Circadian Rhythm; Diabetes Mellitus, Experimental; Gl

1993
Effects of diabetes on cardiac glycogen metabolism in rats.
    Heart and vessels, 1993, Volume: 8, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Diabetes Mellitus, Experimental; Fasting; Glycogen; Hydroxybutyrates

1993
Effects of subbasal insulin infusion on resting and exercise-induced glucose turnover in depancreatized dogs.
    The American journal of physiology, 1993, Volume: 264, Issue:3 Pt 1

    Topics: 3-Hydroxybutyric Acid; Alloxan; Animals; Diabetes Mellitus, Experimental; Dogs; Epoxy Compounds; Fat

1993
The inhibitory action of buformin, a biguanide on gluconeogenesis from alanine and its transport system in rat livers.
    Diabetes research and clinical practice, 1993, Volume: 19, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Alanine; Animals; Biological Transport, Active; Buformin; Cell

1993
Uptake of ketone bodies in perfused hindquarter and kidney of starved, thyrotoxic, and diabetic rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1993, Volume: 203, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Biological Transport; Diabete

1993
Insulin treatment fails to abolish the teratogenic potential of serum from diabetic rats.
    European journal of endocrinology, 1996, Volume: 134, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine Transaminase; Animals; Aspartate Aminotransferases; Blood Glucose; Co

1996
Effect of physical training on mitochondrial function in skeletal muscle of normal and diabetic rats.
    Metabolism: clinical and experimental, 1996, Volume: 45, Issue:7

    Topics: 3-Hydroxybutyric Acid; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Diabetes Mellitus, Ex

1996
Altered renal intermediary metabolism and the onset of renal dysfunction in the streptozotocin diabetic rat.
    Biochemical Society transactions, 1996, Volume: 24, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies;

1996
Altered ovarian sterol carrier protein expression in the pregnant streptozotocin-treated diabetic rat.
    Biology of reproduction, 1996, Volume: 55, Issue:1

    Topics: 3-Hydroxybutyric Acid; 3-Hydroxysteroid Dehydrogenases; Acetyl-CoA C-Acetyltransferase; Animals; Blo

1996
Favourable, significant effect of the dose-dependent treatment with RU 38486 (RU) on the alterations of the hepatic mitochondrial function of diabetic rats.
    Diabetes research and clinical practice, 1996, Volume: 32, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adrenalectomy; Animals; Anti-Inflammatory Agents; Corticosterone; Diabetes Me

1996
Teratogenic effects of diabetes mellitus in the rat. Prevention by vitamin E.
    Diabetologia, 1996, Volume: 39, Issue:9

    Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Cholesterol; Congenital Abnormalities; Diabete

1996
Glucose transport and glucose transporter GLUT4 are regulated by product(s) of intermediary metabolism in cardiomyocytes.
    The Biochemical journal, 1997, Feb-01, Volume: 321 ( Pt 3)

    Topics: 3-Hydroxybutyric Acid; 3-O-Methylglucose; Animals; Biological Transport; Cells, Cultured; Deoxygluco

1997
Direct antidiabetic effect of leptin through triglyceride depletion of tissues.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Apr-29, Volume: 94, Issue:9

    Topics: 3-Hydroxybutyric Acid; Animals; Carrier Proteins; Culture Techniques; Diabetes Mellitus, Experimenta

1997
Beta-hydroxybutyrate increases reactive oxygen species in late but not in early postimplantation embryonic cells in vitro.
    Diabetes, 1998, Volume: 47, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Culture Techniques; Diabetes Mellitus, Experimental; Embryo, Mammali

1998
Effect of insulin on intramuscular 3-hydroxybutyrate levels in diabetic rats.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1998, Volume: 30, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hydroxybutyrates; Hy

1998
Intramuscular 3-hydroxybutyrate levels after 60 tetani/min contraction in diabetic and non-diabetic rats.
    Endocrine journal, 1998, Volume: 45, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Diabetes Mellitus, Experimental; Lactic Acid; Male; Muscle Contracti

1998
Protein turnover in skeletal muscle of the diabetic rat: activation of ubiquitin-dependent proteolysis.
    International journal of molecular medicine, 1998, Volume: 1, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adipose Tissue; Animals; Body Weight; Diabetes Mellitus, Exper

1998
MCT/LCT emulsion ameliorate liver fat deposition in insulin-treated diabetic rats receiving total parenteral nutrition.
    Clinical nutrition (Edinburgh, Scotland), 1998, Volume: 17, Issue:6

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cholesterol; Diabetes Mellitus, Experimental; Diabete

1998
Lipoic acid acutely induces hypoglycemia in fasting nondiabetic and diabetic rats.
    Metabolism: clinical and experimental, 1999, Volume: 48, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Blood Glucose; Carnitine; Diabetes Mellitus, Experimental;

1999
Effects of the dimethyl ester on succinic acid on the hormonal and metabolic response to exercise in hereditarily diabetic starved rats.
    Cell biochemistry and function, 2000, Volume: 18, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Body Weight; Diabetes Mellitus, Experimental; Fatty Acids, Nonesteri

2000
Effect of endogenous beta-hydroxybutyrate on glucose metabolism in the diabetic rabbit brain: a (13)C-magnetic resonance spectroscopy study of [U-(13)C]glucose metabolites.
    Journal of neuroscience research, 2001, Apr-15, Volume: 64, Issue:2

    Topics: 3-Hydroxybutyric Acid; Alloxan; Amino Acids; Animals; Brain; Carbon Isotopes; Diabetes Mellitus, Exp

2001
Simultaneous determination of D-lactic acid and 3-hydroxybutyric acid in rat plasma using a column-switching HPLC with fluorescent derivatization with 4-nitro-7-piperazino-2,1,3-benzoxadiazole (NBD-PZ).
    Biomedical chromatography : BMC, 2001, Volume: 15, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Chromatography, High Pressure Liquid; Diabetes Mellitus, Experimenta

2001
Effect of endogenous beta-hydroxybutyrate on brain glucose metabolism in fetuses of diabetic rabbits, studied by (13)C magnetic resonance spectroscopy.
    Brain research. Developmental brain research, 2002, Apr-30, Volume: 135, Issue:1-2

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Blood Glucose; Brain; Carbon Isotopes; Diabetes Mellitu

2002
Hypoglycemic effects of a beta-agonist, Ro 16-8714, in streptozotocin-diabetic rats: decreased hepatic glucose production and increased glucose utilization in oxidative muscles.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:2

    Topics: 2-Hydroxyphenethylamine; 3-Hydroxybutyric Acid; Adrenergic beta-Agonists; Animals; Diabetes Mellitus

1992
Effects of tolbutamide on fructose-2,6-bisphosphate formation and ketogenesis in hepatocytes from diabetic rats.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fructosediphosphates

1992
Effects of diabetes and insulin on ketone bodies metabolism in heart.
    Molecular and cellular biochemistry, 1992, Mar-04, Volume: 110, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diabetes Mellitus, Experimental; Hydroxybutyrates; In

1992
Malonyl-CoA in skeletal muscle and liver of streptozotocin-diabetic rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 198, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Cyclic AMP; Diabetes Mellitus, Experimental; Fatty Ac

1991
Assay of 3-hydroxybutyrate in the picomolar range.
    Biochemical medicine and metabolic biology, 1991, Volume: 45, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Carbon Radioisotopes; Cattle; Diabetes Mellitus, Experimental; Diazo

1991
Uptake of beta-hydroxybutyrate in perfused hindquarter of starved and diabetic rats.
    Metabolism: clinical and experimental, 1991, Volume: 40, Issue:12

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diabetes Mellitus, Experimental; Glucose; Hindlimb; H

1991
Tumor necrosis factor-increased hepatic very-low-density lipoprotein production and increased serum triglyceride levels in diabetic rats.
    Diabetes, 1990, Volume: 39, Issue:12

    Topics: 3-Hydroxybutyric Acid; Acetyl-CoA Carboxylase; Animals; Blood Glucose; Diabetes Mellitus, Experiment

1990
Secretion of triglyceride and ketogenesis by livers from spontaneous diabetic BB Wistar rats.
    Biochemical and biophysical research communications, 1991, May-15, Volume: 176, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Female;

1991
Effect of diabetes and time after in vivo insulin administration on ketogenesis and gluconeogenesis in isolated rat hepatocytes.
    The International journal of biochemistry, 1990, Volume: 22, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Diabetes Mellitus, Experimental; Gluconeogenesis; Hyd

1990
Validation of two-pool model for in vivo ketone body kinetics.
    The American journal of physiology, 1990, Volume: 258, Issue:5 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Carbon Isotopes; Carbon Radioisotopes; Diabetes Melli

1990
Effects of D-glucose and beta-hydroxybutyric acid on the in vitro development of (pre)chondrocytes from embryos of normal and diabetic rats.
    Acta endocrinologica, 1990, Volume: 122, Issue:4

    Topics: 3-Hydroxybutyric Acid; Animals; Cartilage; Cell Differentiation; Cell Division; Cells, Cultured; Den

1990
Substrate availability other than glucose in the brain during euglycemia and insulin-induced hypoglycemia in dogs.
    Metabolism: clinical and experimental, 1990, Volume: 39, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blood Glucose; Brain; Diabetes Mellitus, Experimental

1990
Gluconeogenesis and the protection of hepatic intracellular pH during diabetic ketoacidosis in rats.
    The Biochemical journal, 1989, Nov-01, Volume: 263, Issue:3

    Topics: 3-Hydroxybutyric Acid; Adenine Nucleotides; Animals; Carbon Dioxide; Diabetes Mellitus, Experimental

1989
Effects of lipolytic and antilipolytic agents on glycerol and free fatty acid release from isolated adipocytes of normal and diabetic rats.
    Nagoya journal of medical science, 1989, Volume: 51, Issue:1-4

    Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Animals; Bucladesine; Diabetes Mellitus, Experimental; Dose-R

1989
Morphological and physiological effects of beta-hydroxybutyrate on rat embryos grown in vitro at different stages.
    Teratology, 1989, Volume: 40, Issue:3

    Topics: 3-Hydroxybutyric Acid; Analysis of Variance; Animals; Diabetes Mellitus, Experimental; Embryo, Mamma

1989
Normal insulin sensitivity during the phase of glucose intolerance but insulin resistance at the onset of diabetes in the spontaneously diabetic BB rat.
    Diabetologia, 1989, Volume: 32, Issue:12

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Crosses, Genetic; Diabetes Mellitus, Experimental; Ep

1989
Glucocorticoid effects on IGF-1/somatomedin-C and somatomedin inhibitor in streptozotocin-diabetic rats.
    Metabolism: clinical and experimental, 1989, Volume: 38, Issue:6

    Topics: 3-Hydroxybutyric Acid; Adrenalectomy; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experi

1989
Evidence for multifactorial origin of diabetes-induced embryopathies.
    Diabetes, 1989, Volume: 38, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Congenital Abnormalities; Diabetes Mellitus, Experimental; Female; F

1989
Regional ketone body utilization by rat brain in starvation and diabetes.
    The American journal of physiology, 1986, Volume: 250, Issue:2 Pt 1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Autoradiography; Brain; Diabetes Mellitus, Experiment

1986
Effects of hypoglycemia and diabetes on fuel metabolism by rat brain microvessels.
    The American journal of physiology, 1988, Volume: 254, Issue:3 Pt 1

    Topics: 3-Hydroxybutyric Acid; Animals; Capillaries; Cerebrovascular Circulation; Diabetes Mellitus, Experim

1988
Effects of diabetes on fructose 2, 6-P2, glucose 1, 6-P2 and 6-phosphofructo 2-kinase in rat liver.
    Biochemical and biophysical research communications, 1986, Apr-29, Volume: 136, Issue:2

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetic Ketoacidosi

1986
Age-related change in ketone body metabolism: diminished glucagon effect on ketogenesis in adult rats.
    Endocrinology, 1987, Volume: 120, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Carnitine; Cyclic AMP; Diabetes Mellitus, Expe

1987
Effect of diabetic ketosis on jejunal glutaminase.
    Archives of biochemistry and biophysics, 1986, Volume: 248, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Diabetes Mellitus, Experimental; Diabetic Ketoacidosis; Fasting; Glu

1986
Possible mechanisms responsible for the rise in plasma vasopressin associated with diabetic ketoacidosis in the rat.
    The Journal of endocrinology, 1988, Volume: 116, Issue:3

    Topics: 3-Hydroxybutyric Acid; Animals; Arginine Vasopressin; Blood Pressure; Diabetes Mellitus, Experimenta

1988
Nutrition and somatomedin. XIV. Altered levels of somatomedins and somatomedin inhibitors in rats with streptozotocin-induced diabetes.
    Metabolism: clinical and experimental, 1985, Volume: 34, Issue:8

    Topics: 3-Hydroxybutyric Acid; Animals; Biological Assay; Blood Glucose; Body Weight; Cartilage; Chromatogra

1985
Effects of diabetes, beta-hydroxybutyric acid and metabolic acidosis on the pituitary-thyroid axis in the rat.
    Journal of endocrinological investigation, 1985, Volume: 8, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acidosis; Ammonium Chloride; Animals; Diabetes Mellitus, Experimental; Hydrox

1985
Hepatic cytochrome P-450j induction in the spontaneously diabetic BB rat.
    Molecular pharmacology, 1988, Volume: 33, Issue:2

    Topics: 3-Hydroxybutyric Acid; Aniline Hydroxylase; Animals; Cytochrome P-450 Enzyme System; Diabetes Mellit

1988
Role of carnitine palmitoyltransferase I in the regulation of hepatic ketogenesis during the onset and reversal of chronic diabetes.
    The Biochemical journal, 1988, Jan-15, Volume: 249, Issue:2

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acyltransferases; Animals; Blood Glucose; Carnitine O-Palmitoy

1988
Direct inhibition of collagen production in vitro by diabetic rat serum.
    Metabolism: clinical and experimental, 1988, Volume: 37, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Cartilage; Collagen; Diabetes Mellitus, Experimental; DNA; Glucose;

1988
Lipogenesis from ketone bodies in perfused livers from streptozocin-induced diabetic rats.
    Diabetes, 1988, Volume: 37, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Coenzyme A Ligases; Diabetes Mellitus, Experimental;

1988
Intermediary metabolism in diabetic dogs treated with pancreatic autotransplants and insulin pumps.
    Metabolism: clinical and experimental, 1986, Volume: 35, Issue:4

    Topics: 3-Hydroxybutyric Acid; Alanine; Animals; Diabetes Mellitus, Experimental; Dogs; Fatty Acids, Noneste

1986
Effects of metabolic factors in the diabetic state on the in vitro development of preimplantation mouse embryos.
    Teratology, 1987, Volume: 35, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Animals; Blastocyst; Culture Techniques; Diabetes Mellitus, Ex

1987
Effect of diabetes, adrenalectomy and hypophysectomy on D-3-hydroxybutyrate dehydrogenase activity and substrate oxidation by rat mitochondria.
    Biochemistry international, 1987, Volume: 14, Issue:1

    Topics: 3-Hydroxybutyric Acid; Adrenalectomy; Animals; Diabetes Mellitus, Experimental; Hydroxybutyrate Dehy

1987
Effects of oral hypoglycemic agent methylpalmoxirate on exercise capacity of streptozocin diabetic rats.
    Diabetes, 1986, Volume: 35, Issue:7

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Epoxy Compounds; Eth

1986
Renal beta-hydroxybutyrate (beta OHB) transport in streptozotocin (Sz)-induced diabetic rats.
    Annals of the New York Academy of Sciences, 1985, Volume: 456

    Topics: 3-Hydroxybutyric Acid; Absorption; Animals; Biological Transport, Active; Diabetes Mellitus, Experim

1985
Relationship between maternal and fetal fuels and placental glucose transfer in rats with maternal diabetes of varying severity.
    Diabetes, 1985, Volume: 34 Suppl 2

    Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Female;

1985
Elevated levels of vasoactive intestinal peptide in the eye and urinary bladder of diabetic and prediabetic Chinese hamsters.
    Diabetologia, 1985, Volume: 28, Issue:5

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Body Weight; Cricetinae; Cricetulus; Diabetes Mellitu

1985